Natalya A. Shchukina
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Natalya A. Shchukina has a total of 47 co-authors. Here are the top co-authors by number of shared publications:
- Svetlana Nikolaevna Buyanova
V.I. Krasnopolsky Moscow Regional Scientific Research Institute of Obstetrics and Gynecology
10 shared publications - Timur Alekseevich Glebov
Moscow Regional Research Institute of Obstetrics and Gynecology named after Academician V.I. Krasnopolsky
9 shared publications - Evgeniya Leonidovna Babunashvili
Moscow Regional Research Institute of Obstetrics and Gynecology
8 shared publications - N.YU. Zemskova
Moscow Regional Research Institute of Obstetrics and Gynecology
4 shared publications - Tatyana Sergeevna Budykina
V.I. Krasnopolsky Moscow Regional Research Institute of Obstetrics and Gynecology
4 shared publications - A.A. Kochetkova
Moscow Regional Research Institute of Obstetrics and Gynecology
3 shared publications
Latest Publications
- 10 June 2025
- Published by Media Sphere Publishing Group in Russian Bulletin of Obstetrician-Gynecologist
- Vol. 25 (3)
Perineal endometriosis after delivery: causes of development, treatment, prevention
Objective. To reduce the risk of perineal endometriosis after delivery, as well as the recurrence rate of this disease by developing diagnostic and treatment algorithms. Material and methods. A retrospective study of 40 patients with perineal endometriosis who underwent surgical treatment in the department of operative gynecology with oncogynecology and day hospital of the Moscow Regional Research Institute of Obstetrics and Gynecology named after Academician V.I. Krasnopolsky (MONIIAG) in the period from 2015 to 2023 (group 1) was conducted. In addition, 25 patients without perineal endometriosis with physiologic course of labor (2nd additional clinical group) were examined. Results. Risk factors for the development of perineal endometriosis were identified. Diagnosis of endometrioid infiltrates, as a rule, was late, which is associated with the late appearance of clinical signs and late referral to a gynecologist. Ultrasound examination allows you to determine the size, localization and structure of the infiltrate. In the presence of multiple foci of different sizes, especially recurrent, MRI is preferable. Treatment of perineal endometriosis is surgical. Conclusion. Perineal endometriosis after delivery is a delayed complication. Thorough diagnostics based on instrumental methods of investigation allows to optimize surgical treatment tactics. Hormonal therapy of perineal endometrioid infiltrates at pre- and postoperative stages does not lead to clinically significant changes in the course of the disease, only careful observance of the technology of surgical removal of masses can reduce the risk of disease recurrence.
- 10 June 2025
- Published by Media Sphere Publishing Group in Russian Bulletin of Obstetrician-Gynecologist
- Vol. 25 (3)
Perineal endometriosis after delivery: causes of development, treatment, prevention
Objective. To reduce the risk of perineal endometriosis after delivery, as well as the recurrence rate of this disease by developing diagnostic and treatment algorithms. Material and methods. A retrospective study of 40 patients with perineal endometriosis who underwent surgical treatment in the department of operative gynecology with oncogynecology and day hospital of the Moscow Regional Research Institute of Obstetrics and Gynecology named after Academician V.I. Krasnopolsky (MONIIAG) in the period from 2015 to 2023 (group 1) was conducted. In addition, 25 patients without perineal endometriosis with physiologic course of labor (2nd additional clinical group) were examined. Results. Risk factors for the development of perineal endometriosis were identified. Diagnosis of endometrioid infiltrates, as a rule, was late, which is associated with the late appearance of clinical signs and late referral to a gynecologist. Ultrasound examination allows you to determine the size, localization and structure of the infiltrate. In the presence of multiple foci of different sizes, especially recurrent, MRI is preferable. Treatment of perineal endometriosis is surgical. Conclusion. Perineal endometriosis after delivery is a delayed complication. Thorough diagnostics based on instrumental methods of investigation allows to optimize surgical treatment tactics. Hormonal therapy of perineal endometrioid infiltrates at pre- and postoperative stages does not lead to clinically significant changes in the course of the disease, only careful observance of the technology of surgical removal of masses can reduce the risk of disease recurrence.
- 22 October 2024
- Published by Media Sphere Publishing Group in Russian Bulletin of Obstetrician-Gynecologist
- Vol. 24 (5)
Controversial issues of adjuvant therapy after myomectomy
Uterine fibroids are one of the most common tumors of the female reproductive system. In this article, based on the latest domestic and world publications and clinical recommendations of the Russian Federation, the issues of adjuvant therapy in patients with uterine fibroids after myomectomy (the use of GnRH agonists-antagonist and selective progesterone receptor modulators — SPRM) are highlighted.
- 22 October 2024
- Published by Media Sphere Publishing Group in Russian Bulletin of Obstetrician-Gynecologist
- Vol. 24 (5)
Controversial issues of adjuvant therapy after myomectomy
Uterine fibroids are one of the most common tumors of the female reproductive system. In this article, based on the latest domestic and world publications and clinical recommendations of the Russian Federation, the issues of adjuvant therapy in patients with uterine fibroids after myomectomy (the use of GnRH agonists-antagonist and selective progesterone receptor modulators — SPRM) are highlighted.
- Open Access
- 15 December 2023
- Published by Baltic Medical Education Center in Marine Medicine
- Vol. 9 (4) , 63-71
Inhalation of heated oxigen-helium mixture in treating obstetrtic and gynecological pathology: prospective experimental study
INTRODUCTION. The heated oxygen-helium mixture has found application in treating acute respiratory failure in patients with the exacerbation of chronic obstructive pulmonary disease, postextubation stridor, croup and viral bronchiolitis in children, acute respiratory distress syndrome in newborns. The article presents the results of own study according to the results of applying inhalations of the heated oxygen-helium mixture (oxygen 30%, helium 70%) in order to improve reparative processes in postoperative gynecological cases (after myomectomy) and to treat placental insufficiency in pregnant women with diseases of the bronchopulmonary system. OBJECTIVE. То estimate efficacy of the heated oxygen-helium mixture on the reproductive health of pregnant women with bronchopulmonary pathology and gynecological cases with patients of reproductive age after myomectomy. RESULTS. Against the background of the treatment, there was an increase in blood oxygen saturation, normalization of indicators of fetoplacental hemodynamics and hormonal function of fetoplacental complex in pregnant women. Inhalations of the heated oxygen-helium mixture in gynecological cases after myomectomy led to an increase in blood flow velocity in the area of ligatures. CONCLUSION. The study has shown that the method of inhalation through the heated oxygen-helium mixture (70% helium, 30% oxygen) is effective, safe and prospective for applying in obstetric and gynecological practice.
- 15 December 2023
- Published by Baltic Medical Education Center in Marine Medicine
- Vol. 9 (4) , 63-71
Open AccessInhalation of heated oxigen-helium mixture in treating obstetrtic and gynecological pathology: prospective experimental study
INTRODUCTION. The heated oxygen-helium mixture has found application in treating acute respiratory failure in patients with the exacerbation of chronic obstructive pulmonary disease, postextubation stridor, croup and viral bronchiolitis in children, acute respiratory distress syndrome in newborns. The article presents the results of own study according to the results of applying inhalations of the heated oxygen-helium mixture (oxygen 30%, helium 70%) in order to improve reparative processes in postoperative gynecological cases (after myomectomy) and to treat placental insufficiency in pregnant women with diseases of the bronchopulmonary system. OBJECTIVE. То estimate efficacy of the heated oxygen-helium mixture on the reproductive health of pregnant women with bronchopulmonary pathology and gynecological cases with patients of reproductive age after myomectomy. RESULTS. Against the background of the treatment, there was an increase in blood oxygen saturation, normalization of indicators of fetoplacental hemodynamics and hormonal function of fetoplacental complex in pregnant women. Inhalations of the heated oxygen-helium mixture in gynecological cases after myomectomy led to an increase in blood flow velocity in the area of ligatures. CONCLUSION. The study has shown that the method of inhalation through the heated oxygen-helium mixture (70% helium, 30% oxygen) is effective, safe and prospective for applying in obstetric and gynecological practice.
- 23 April 2023
- Published by Media Sphere Publishing Group in Russian Bulletin of Obstetrician-Gynecologist
- Vol. 23 (6)
Methods of prevention of vaginal intraepithelial neoplasia in HPV-positive patients under radical surgery
In the review of scientific literature the methods of prophylaxis of vaginal intraepithelial neoplasia in HPV-positive patients, including those who underwent hysterectomy for diseases of the uterine body and cervix, are highlighted. In most cases, vaginal intraepithelial neoplasia developed in the upper third of the vagina, and the middle and lower thirds were affected in less than 10% of cases. Intraepithelial vaginal neoplasia provoked by insufficient excision of the vaginal wall during hysterectomy was detected in 39.5% of patients. Despite radical volumes of operations in surgical treatment of diseases of the body and cervix (hysterectomy), vaginal cancer was observed especially often in HPV-positive patients. Vaginal resection in HPV-positive patients during hysterectomy may be a method of vaginal cancer prevention.
- 23 April 2023
- Published by Media Sphere Publishing Group in Russian Bulletin of Obstetrician-Gynecologist
- Vol. 23 (6)
Methods of prevention of vaginal intraepithelial neoplasia in HPV-positive patients under radical surgery
In the review of scientific literature the methods of prophylaxis of vaginal intraepithelial neoplasia in HPV-positive patients, including those who underwent hysterectomy for diseases of the uterine body and cervix, are highlighted. In most cases, vaginal intraepithelial neoplasia developed in the upper third of the vagina, and the middle and lower thirds were affected in less than 10% of cases. Intraepithelial vaginal neoplasia provoked by insufficient excision of the vaginal wall during hysterectomy was detected in 39.5% of patients. Despite radical volumes of operations in surgical treatment of diseases of the body and cervix (hysterectomy), vaginal cancer was observed especially often in HPV-positive patients. Vaginal resection in HPV-positive patients during hysterectomy may be a method of vaginal cancer prevention.
- 23 April 2023
- Published by Media Sphere Publishing Group in Russian Bulletin of Obstetrician-Gynecologist
- Vol. 23 (6)
Use of heated oxygen-helium mixture at the stage of rehabilitation in patients after myomectomy
ЦЕЛЬ ИССЛЕДОВАНИЯ Оценка эффекта от воздействия ингаляций подогретой кислородно-гелиевой смеси на кислотно-основное состояние (КОС) организма, микроциркуляцию и процессы репарации в зоне послеоперационного шва на матке после миомэктомии. МАТЕРИАЛ И МЕТОДЫ В 2021—2022 гг. в ГБУЗ МО «МОНИИАГ» 30 пациенток в возрасте от 25 до 45 лет после лапаротомной миомэктомии получали ингаляции подогретой кислородно-гелиевой смеси в течение 10 мин 1 раз в сутки на протяжении 5 дней. Известно, что эту методику используют для лечения пациентов с заболеваниями сердечно-сосудистой, нервной, дыхательной систем, особенно при тяжелом поражении легких коронавирусной инфекцией COVID-19. РЕЗУЛЬТАТЫ Оценка допплерометрических показателей зоны операции (области швов на матке) и КОС крови на фоне лечения показала статистически значимое снижение концентрации CO2 с 35,69 до 34,52 мм рт.ст. (p2 с 7,77 до 71,4 мм рт.ст. (ppp<0,0022). Не было зарегистрировано ни одного нежелательного явления, связанного с применением препарата. ЗАКЛЮЧЕНИЕ Улучшенные показатели гемодинамики, оксигенации крови, утеротонический эффект способствовали устранению ишемии в области операции за счет нормализации микроциркуляции и насыщения тканей кислородом, что способствовало благополучной репарации зоны хирургического вмешательства.
- 23 April 2023
- Published by Media Sphere Publishing Group in Russian Bulletin of Obstetrician-Gynecologist
- Vol. 23 (6)
Use of heated oxygen-helium mixture at the stage of rehabilitation in patients after myomectomy
ЦЕЛЬ ИССЛЕДОВАНИЯ Оценка эффекта от воздействия ингаляций подогретой кислородно-гелиевой смеси на кислотно-основное состояние (КОС) организма, микроциркуляцию и процессы репарации в зоне послеоперационного шва на матке после миомэктомии. МАТЕРИАЛ И МЕТОДЫ В 2021—2022 гг. в ГБУЗ МО «МОНИИАГ» 30 пациенток в возрасте от 25 до 45 лет после лапаротомной миомэктомии получали ингаляции подогретой кислородно-гелиевой смеси в течение 10 мин 1 раз в сутки на протяжении 5 дней. Известно, что эту методику используют для лечения пациентов с заболеваниями сердечно-сосудистой, нервной, дыхательной систем, особенно при тяжелом поражении легких коронавирусной инфекцией COVID-19. РЕЗУЛЬТАТЫ Оценка допплерометрических показателей зоны операции (области швов на матке) и КОС крови на фоне лечения показала статистически значимое снижение концентрации CO2 с 35,69 до 34,52 мм рт.ст. (p2 с 7,77 до 71,4 мм рт.ст. (ppp<0,0022). Не было зарегистрировано ни одного нежелательного явления, связанного с применением препарата. ЗАКЛЮЧЕНИЕ Улучшенные показатели гемодинамики, оксигенации крови, утеротонический эффект способствовали устранению ишемии в области операции за счет нормализации микроциркуляции и насыщения тканей кислородом, что способствовало благополучной репарации зоны хирургического вмешательства.
- 23 April 2023
- Published by Media Sphere Publishing Group in Russian Bulletin of Obstetrician-Gynecologist
- Vol. 23 (5)
Proliferative diseases of the uterus. What to prefer in the postoperative rehabilitation program?
Proliferative uterine diseases (uterine myoma, endometriosis) and their combination are not uncommon pathology, which, along with surgery, requires a medical component of treatment. This article highlights new aspects of clinical manifestations of these diseases («rejuvenation» of the contingent, increase in the frequency of rare forms of endometriosis — its affection of the anterior abdominal wall and uterine scar), on the basis of the latest clinical recommendations of the Russian Federation on the treatment of patients with uterine myoma, endometriosis, as well as on the basis of many years of our own experience of treatment and postoperative rehabilitation of patients are considered and given variants of differentiated postoperative drug therapy (gonadotropin-releasing hormone agonists).
- 23 April 2023
- Published by Media Sphere Publishing Group in Russian Bulletin of Obstetrician-Gynecologist
- Vol. 23 (5)
Proliferative diseases of the uterus. What to prefer in the postoperative rehabilitation program?
Proliferative uterine diseases (uterine myoma, endometriosis) and their combination are not uncommon pathology, which, along with surgery, requires a medical component of treatment. This article highlights new aspects of clinical manifestations of these diseases («rejuvenation» of the contingent, increase in the frequency of rare forms of endometriosis — its affection of the anterior abdominal wall and uterine scar), on the basis of the latest clinical recommendations of the Russian Federation on the treatment of patients with uterine myoma, endometriosis, as well as on the basis of many years of our own experience of treatment and postoperative rehabilitation of patients are considered and given variants of differentiated postoperative drug therapy (gonadotropin-releasing hormone agonists).
- 14 April 2023
- Published by Media Sphere Publishing Group in Russian Bulletin of Obstetrician-Gynecologist
- Vol. 23 (2)
Artificial intelligence in pregnancy prediction
Objective. To study the power of artificial intelligence in predicting the onset of pregnancy by evaluating patients’ hormonal status and medical history. Material and methods. A retrospective analysis was made of 334 case histories of patients aged 20 to 48 years who underwent in vitro fertilization (excluding cryoprocedures) between July 2011 and January 2019 using the SPERO-screen software algorithm. Results. The probability of pregnancy on dates significantly different from the software-calculated dates is significantly lower than the data reported in the world literature. Use of the data analysis algorithm created on the basis of artificial intelligence makes it possible to increase the probability of pregnancy by more than 2-fold. Conclusion. On the basis of the analysis of a woman’s hormonal status and anamnesis data with the application of machine learning technologies with the application of artificial neural networks, prepared on the basis of thousands of clinical cases of successful pregnancy, it is possible to predict the most favorable menstrual cycles and specific dates of conception.
- 14 April 2023
- Published by Media Sphere Publishing Group in Russian Bulletin of Obstetrician-Gynecologist
- Vol. 23 (2)
Artificial intelligence in pregnancy prediction
Objective. To study the power of artificial intelligence in predicting the onset of pregnancy by evaluating patients’ hormonal status and medical history. Material and methods. A retrospective analysis was made of 334 case histories of patients aged 20 to 48 years who underwent in vitro fertilization (excluding cryoprocedures) between July 2011 and January 2019 using the SPERO-screen software algorithm. Results. The probability of pregnancy on dates significantly different from the software-calculated dates is significantly lower than the data reported in the world literature. Use of the data analysis algorithm created on the basis of artificial intelligence makes it possible to increase the probability of pregnancy by more than 2-fold. Conclusion. On the basis of the analysis of a woman’s hormonal status and anamnesis data with the application of machine learning technologies with the application of artificial neural networks, prepared on the basis of thousands of clinical cases of successful pregnancy, it is possible to predict the most favorable menstrual cycles and specific dates of conception.
- 1 January 2022
- Published by Media Sphere Publishing Group in Russian Bulletin of Obstetrician-Gynecologist
- Vol. 22 (6)
Current approaches to drug therapy in patients with concomitant proliferative uterine diseases
Сочетанные доброкачественные пролиферативные заболевания матки (миома матки, эндометриоз, гиперплазия эндометрия) — нередкая патология (25—85%), которая, наряду с хирургическим, требует медикаментозного компонента лечения. В данной статье, на основе последних клинических рекомендаций РФ по лечению пациенток с миомой матки, эндометриозом, гиперплазией эндометрия, рекомендаций по ведению сочетанных доброкачественных опухолей и гиперпластических процессов матки, а также на основе многолетнего собственного опыта послеоперационной реабилитации пациенток с сочетанными пролиферативными заболеваниями рассматриваются и приводятся возможные варианты медикаментозной терапии (агонисты гонадотропин-рилизинг-гормона, диеногест, прогестагены, комбинированные оральные контрацептивы, левоноргестрел в форме внутриматочной терапевтической системы), при этом только индивидуальный дифференцированный подход с учетом многих факторов позволяет решать сложные клинические задачи.
- 1 January 2022
- Published by Media Sphere Publishing Group in Russian Bulletin of Obstetrician-Gynecologist
- Vol. 22 (6)
Current approaches to drug therapy in patients with concomitant proliferative uterine diseases
Сочетанные доброкачественные пролиферативные заболевания матки (миома матки, эндометриоз, гиперплазия эндометрия) — нередкая патология (25—85%), которая, наряду с хирургическим, требует медикаментозного компонента лечения. В данной статье, на основе последних клинических рекомендаций РФ по лечению пациенток с миомой матки, эндометриозом, гиперплазией эндометрия, рекомендаций по ведению сочетанных доброкачественных опухолей и гиперпластических процессов матки, а также на основе многолетнего собственного опыта послеоперационной реабилитации пациенток с сочетанными пролиферативными заболеваниями рассматриваются и приводятся возможные варианты медикаментозной терапии (агонисты гонадотропин-рилизинг-гормона, диеногест, прогестагены, комбинированные оральные контрацептивы, левоноргестрел в форме внутриматочной терапевтической системы), при этом только индивидуальный дифференцированный подход с учетом многих факторов позволяет решать сложные клинические задачи.
- 1 January 2022
- Published by Media Sphere Publishing Group in Russian Bulletin of Obstetrician-Gynecologist
- Vol. 22 (5)
A method for surgical treatment of patients with medium and/or high rectocele
ЦЕЛЬ ИССЛЕДОВАНИЯ Создать надежный способ хирургической коррекции среднего и высокого ректоцеле, значительно снижающий число рецидивов или не сопровождающийся рецидивами заболевания. МАТЕРИАЛ И МЕТОДЫ Предложен хирургический способ пластики тазового дна, основанный на восстановлении целостности ректовагинальной фасции путем подшивания ее к крестцово-маточным связкам, усилении прочности ректовагинальной перегородки пучками мышц, поднимающих задний проход, что обеспечивает фиксацию и поддержку пролабирующих стенок влагалища и прямой кишки. С использованием этого метода прооперированы 25 пациенток со средним и высоким ректоцеле II—III стадии в возрасте от 34 до 48 лет. Срок наблюдения за оперированными пациентками составил от 2 мес до 2 лет. РЕЗУЛЬТАТЫ Во всех наблюдениях рецидивов пролапса тазовых органов не отмечено. Стояние задней стенки влагалища соответствовало физиологическим нормам. Отмечено улучшение эвакуаторной функции прямой кишки. ЗАКЛЮЧЕНИЕ Предложенная пластика задней стенки влагалища с реконструкцией ректовагинальной перегородки создает прочную мышечно-фасциальную структуру между передней стенкой прямой кишки и слизистой оболочкой задней стенки влагалища, является высокоэффективной, позволяет значительно улучшить качество жизни пациенток и может служить методом выбора в лечении больных с высоким и средним ректоцеле.
- 1 January 2022
- Published by Media Sphere Publishing Group in Russian Bulletin of Obstetrician-Gynecologist
- Vol. 22 (5)
A method for surgical treatment of patients with medium and/or high rectocele
ЦЕЛЬ ИССЛЕДОВАНИЯ Создать надежный способ хирургической коррекции среднего и высокого ректоцеле, значительно снижающий число рецидивов или не сопровождающийся рецидивами заболевания. МАТЕРИАЛ И МЕТОДЫ Предложен хирургический способ пластики тазового дна, основанный на восстановлении целостности ректовагинальной фасции путем подшивания ее к крестцово-маточным связкам, усилении прочности ректовагинальной перегородки пучками мышц, поднимающих задний проход, что обеспечивает фиксацию и поддержку пролабирующих стенок влагалища и прямой кишки. С использованием этого метода прооперированы 25 пациенток со средним и высоким ректоцеле II—III стадии в возрасте от 34 до 48 лет. Срок наблюдения за оперированными пациентками составил от 2 мес до 2 лет. РЕЗУЛЬТАТЫ Во всех наблюдениях рецидивов пролапса тазовых органов не отмечено. Стояние задней стенки влагалища соответствовало физиологическим нормам. Отмечено улучшение эвакуаторной функции прямой кишки. ЗАКЛЮЧЕНИЕ Предложенная пластика задней стенки влагалища с реконструкцией ректовагинальной перегородки создает прочную мышечно-фасциальную структуру между передней стенкой прямой кишки и слизистой оболочкой задней стенки влагалища, является высокоэффективной, позволяет значительно улучшить качество жизни пациенток и может служить методом выбора в лечении больных с высоким и средним ректоцеле.