Jinglin Huang
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Previous Organizations / Institutes
The organizations / institutes from the scholar's other articles in the past ten years
Jinglin Huang has a total of 5 co-authors. Here are the top co-authors by number of shared publications:
- Carmen Say
Biochemistry Program, Smith College, Northampton, MA 01063, USA
1 shared publication - Jing Zhang
Synthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA
1 shared publication - Kate T. Queeney
Department of Chemistry, Smith College, Northampton, MA 01063, USA
1 shared publication - Morteza Gharib
California Institute of Technology
1 shared publication - Robert L. Dorit
Department of Biological Sciences, Smith College, Northampton, MA 01063, USA
1 shared publication
Latest Publications
- 26 May 2020
- Published by Springer Nature in Annals of Biomedical Engineering
- Vol. 49 (1) , 251-261
Thermal Effects on Fluid Mixing in the Eye
Age-related macular degeneration (AMD) is the leading cause of central vision loss in the developed world. Wet AMD can be managed through serial intravitreal injections of anti-vascular endothelial growth factor (anti-VEGF) agents. However, sometimes the treatment is ineffective. Given that the half-life of the drug is limited, inefficient mixing of the injected drug in the vitreous chamber of the eye may contribute to the ineffectiveness. Here, we introduce thermal heating as a means of enhancing the mixing-process in the vitreous chamber and investigate parameters that potentially influence its effectiveness. Our in vitro studies reveal the importance of the heating location on the eye. A significant increase in the mixing and delivery of drugs to the targeted area (the macula) could be achieved by placing heating pads to induce a current, against gravity, in the vitreous. The presented results can potentially help in the development of a better strategy for intravitreal injection, subsequently improving the quality of patient care.
- 26 May 2020
- Published by Springer Nature in Annals of Biomedical Engineering
- Vol. 49 (1) , 251-261
Thermal Effects on Fluid Mixing in the Eye
Age-related macular degeneration (AMD) is the leading cause of central vision loss in the developed world. Wet AMD can be managed through serial intravitreal injections of anti-vascular endothelial growth factor (anti-VEGF) agents. However, sometimes the treatment is ineffective. Given that the half-life of the drug is limited, inefficient mixing of the injected drug in the vitreous chamber of the eye may contribute to the ineffectiveness. Here, we introduce thermal heating as a means of enhancing the mixing-process in the vitreous chamber and investigate parameters that potentially influence its effectiveness. Our in vitro studies reveal the importance of the heating location on the eye. A significant increase in the mixing and delivery of drugs to the targeted area (the macula) could be achieved by placing heating pads to induce a current, against gravity, in the vitreous. The presented results can potentially help in the development of a better strategy for intravitreal injection, subsequently improving the quality of patient care.
- Open Access
- 1 June 2018
- Published by Elsevier in Journal of Colloid and Interface Science
- Vol. 519, 203-213
Deconvoluting the effects of surface chemistry and nanoscale topography: Pseudomonas aeruginosa biofilm nucleation on Si-based substrates
- 1 June 2018
- Published by Elsevier in Journal of Colloid and Interface Science
- Vol. 519, 203-213
Open AccessDeconvoluting the effects of surface chemistry and nanoscale topography: Pseudomonas aeruginosa biofilm nucleation on Si-based substrates