Batool Shahraki Mojahed

BackgroundLabor pain is one of the most painful experiences in a women's life. One of the methods of pain relief is spinal anesthesia. The purpose of this study was to evaluate the effect of spinal anesthesia with sufentanil on the length of the first and second stages of labor in singleton pregnant women. MethodsA randomized clinical trial was conducted involving 56 women who had to be at least 37 weeks pregnant with a singleton pregnancy and 20 to 35 years of age, as well as seeking a spontaneous natural delivery. They were randomized into an intervention group (spinal anesthesia with sufentanil) of 28 subjects and a control group (no spinal anesthesia) of 28 subjects. Statistical analysis was performed using SPSS software program 20.0. ResultsMean duration of stage I of labor was 152.32 ± 92.01 and 187.68 ± 121.01 minutes in the intervention and control groups, respectively (p=0.34), whereas mean duration of stage II of labor in the 2 groups was 15.96 ± 14.26 and 26.43 ± 20.90 minutes, respectively (p=0.06). Twenty five percent of women in the intervention group and 35.71% of women in the control group experienced a long stage I, whereas 21.43% of women in the intervention group and 35.71% of women in the control group experienced a long stage II (p>0.05). ConclusionThis study suggests that spinal anesthesia with sufentanil does not increase the duration of labor stages. It is recommended that more studies be performed in the future using larger sample sizes to allow for the drawing of solid conclusions.

Purpose The aim of this study was to evaluate whether the prevalence of celiac among attention-deficit/hyperactivity disorder (ADHD) patients is higher than among the normal population. Methods The present study was a prospective one investigating ADHD children referred to the Neurology...

The situation of Covid-19 patients with opium consumption has not been comprehensively investigated especially in Iran. This study is aimed to investigate the effect of current opium addiction on the severity and outcome of the Covid-19 infection. During a retrospective cohort study, clinical, demographic and all variables related to the severity and death due to the Corona virus infection were collected from the medical records of patients hospitalized from February 2020 to June 2021 in the study area. The role of current addiction in the severity and outcome of the disease was investigated using Cox, logistic and linear regression models. Of 939 confirmed Covid-19 cases admitted during the study period, 70 (7.5%) patients were currently addicted. Multivariate reg­ression models showed that current opium addiction significantly increased the chance of endotracheal intubation (OR=2.96, p=0.005) and reduced the mean length of stay in hospital (beta coefficient =-0.42, p0.99). Opium addiction can be associated with the severity of Covid-19 infection, but does not play a considerable role in the mortality of the patients.

A perfect anesthesia technique is one in which anesthesia can be done in the shortest possible time with minimal hemodynamic changes and side effects This study is aimed to investigate the effects of concomitant administration of dexamethasone with bupivacaine on the duration of anesthesia and the quality of anesthesia-induced in patients undergoing cesarean section. This is a quasi-experimental study done on patients undergoing cesarean section by spinal anesthesia. All patients underwent standard monitoring after admission, then Ringer serum (5 cc/kg) was administered to the patients. The patients was then seated and subjected to intrathecal anesthesia with a midline approach in L3-L4 space. Patients were matched for baseline conditions. After recording background information, type and dosage of drugs used, blood pressure, heart rate, number and frequency of nausea and vomiting were listed in the checklist, and the data were analyzed using SPSS software. In this study, 70 pregnant women who were candidates for cesarean section were included. All our studied parameters, including the mean time to the start of analgesia, mean time of analgesia duration, analgesia duration, mean time to first request for analgesics were significantly improved among the intervention group. The use of dexamethasone and bupivacaine to induce spinal anesthesia during cesarean section can significantly shorten the onset time of analgesia and reduce postoperative nausea and vomiting. Dexamethasone can be used as an effective drug in cesarean section.

Плацентарно-ассоциированный белок плазмы (Placental associated plasma protein A — PAPP-A) является маркером диагностики угрожающих преждевременных родов и неблагоприятных исходов беременности (самопроизвольного аборта). ЦЕЛЬ ИССЛЕДОВАНИЯ Изучение связи между уровнями PAPP-A в сыворотке крови у пациенток на 11—14-й неделе беременности и частотой самопроизвольных абортов и преждевременных родов. МАТЕРИАЛ И МЕТОДЫ В настоящее исследование были включены 827 пациенток в сроке беременности 11—14 нед, направленных в акушерскую клинику больницы. Был изучен их полный медицинский и акушерский анамнез. Затем были оценены и зарегистрированы первые скрининговые тесты, включая PAPP-A. Распространенность неблагоприятных исходов беременности оценивалась в трех группах на основании их связи с уровнями PAPP-A. Проведена статистическая обработка данных, введенных в программное обеспечение SPSS для анализа. РЕЗУЛЬТАТЫ Наблюдалась достоверная разница в средних уровнях PAPP-A среди пациенток, у которых развился каждый из изученных неблагоприятных исходов: преждевременные роды, экстремально ранние преждевременные роды и самопроизвольный аборт. Распространенность всех трех различных неблагоприятных исходов была достоверно выше среди пациенток в группе с самым низким уровнем PAPP-A MOM (pp=0,37), 50% (p=0,011) и 93% (p=001). Область под кривой связи чувствительности и специфичности (ROC) для самопроизвольных абортов значительно выше, чем для преждевременных и экстремально ранних преждевременных родов. ЗАКЛЮЧЕНИЕ Настоящее исследование показало достоверную связь между низким уровнем PAPP-A и более высоким риском развития преждевременных родов, экстремально ранних преждевременных родов и самопроизвольных абортов. Согласно этим результатам предлагается использовать уровень PAPP-A в качестве точного маркера для прогнозирования неблагоприятных исходов беременности.

Introduction: Metabolic syndrome as one of the risk factors for cardiovascular diseases has recently been the focus of clinical studies. This study was conducted to determine the prevalence of metabolic syndrome in hemodialysis patients in Iran. Methods: The present systematic review was done using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist. Case-control, cohort and crosssectional studies conducted in Iran were included. Clinical trials, case reports, letters to editors, systematic reviews, study protocols, narrative reviews, and case series were excluded. Subgroup analysis was conducted for determining the heterogeneity based on the participants as well as their gender. Meta-analysis was conducted using STATA version 14.0. Results: The prevalence of metabolic syndrome among 799 patients was 50% (95% CI: 47.0, 53.0, I2=50.6). The analysis of subgroups was conducted for determining the heterogeneity based on the participants as well as their gender. Based on the analysis of the subgroups using a random effects model, the prevalence of metabolic syndrome was found to be 44% and 55% in Iranian men and women undergoing hemodialysis, respectively. Conclusion: Given the high prevalence of metabolic syndrome in hemodialysis patients, it is advisable and logical that patients with chronic renal failure should be regularly evaluated for metabolic syndrome and cardiovascular risk factors both at the diagnosis time and afterwards.