Teng Cao
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Teng Cao has a total of 5 co-authors. Here are the top co-authors by number of shared publications:
- Ildikó Galambos
Research and Development Center, University of Pannonia, Nagykanizsa, Hungary
2 shared publications Arijit Nath
Hungarian University of Agriculture and Life Sciences Department of Food Process Engineering Ménesi Street 44 1118 Budapest Hungary
1 shared publication- Melinda Pázmándi
Magyar Agrár- és Élettudományi Egyetem
1 shared publication - Zoltán Kovács
Department of Food Engineering, Szent István University, Budapest, Hungary
1 shared publication - Zoltán Kovács
Hungarian University of Agriculture and Life Sciences Department of Food Process Engineering Ménesi Street 44 1118 Budapest Hungary
1 shared publication
Latest Publications
- Open Access
- 11 March 2024
- Published by Wiley in Chemie Ingenieur Technik
- Vol. 96 (4) , 389-400
Production of Galacto‐Oligosaccharides by Enzymatic Membrane Reactors Using Free β‐Galactosidase
Prebiotic galacto‐oligosaccharides (GOSs) are synthesized by transgalactosylation of lactose using β‐galactosidases. Well‐established, large‐scale production of GOS is performed by stirred‐tank reactors (STR) operating in batch fashion. Main manufacturing expenses are attributed to enzyme purchase costs and the downstream operations required for subsequent enzyme inactivation and removal. In the last decades, several studies and patents have appeared on free enzyme membrane reactor (FEMR) as an economic alternative to STR due to enhanced enzyme recovery and reuse. In this review, we attempt to summarize the key design aspects, the catalytic performance and efficiency of FEMR compared to STR technology, and the main concerns related to stable product quality over long‐term operation.
- 11 March 2024
- Published by Wiley in Chemie Ingenieur Technik
- Vol. 96 (4) , 389-400
Open AccessProduction of Galacto‐Oligosaccharides by Enzymatic Membrane Reactors Using Free β‐Galactosidase
Prebiotic galacto‐oligosaccharides (GOSs) are synthesized by transgalactosylation of lactose using β‐galactosidases. Well‐established, large‐scale production of GOS is performed by stirred‐tank reactors (STR) operating in batch fashion. Main manufacturing expenses are attributed to enzyme purchase costs and the downstream operations required for subsequent enzyme inactivation and removal. In the last decades, several studies and patents have appeared on free enzyme membrane reactor (FEMR) as an economic alternative to STR due to enhanced enzyme recovery and reuse. In this review, we attempt to summarize the key design aspects, the catalytic performance and efficiency of FEMR compared to STR technology, and the main concerns related to stable product quality over long‐term operation.
- Open Access
Continuous Production of Galacto-Oligosaccharides by an Enzyme Membrane Reactor Utilizing Free Enzymes
Galacto-oligosaccharides (GOS) are prebiotic compounds widely used for their health-promoting effects. Conventionally, GOS is produced by the enzymatic conversion of lactose in stirred tank reactors (STR). The high operational costs associated with enzyme inactivation and removal might be reduced by the application of enzyme membrane reactors (EMR). In this study, we aimed to assess the potential of continuous GOS production by EMR using soluble Biolacta N5, a Bacillus circulans-derived commercial enzyme preparation. The steady-state performance of the EMR equipped with an ultrafiltration module was investigated as function of residence time (1.1–2.8 h) and enzyme load (17–190 U·g−1) under fixed operational settings of temperature (50 °C), pH (6.0), lactose feed concentration (300 g·kg−1), and recirculation flow-rate (0.18 m3·h−1). Results indicate that the yield of oligosaccharides with higher degree of polymerization (DP3-6) in STR (approx. 38% on total carbohydrate basis) exceeds that measured in EMR (ranging from 24% to 33%). However, a stable catalytic performance without a significant deterioration in product quality was observed when operating the EMR for an extended period of time (>120 h). Approx. 1.4 kg of DP3-6 was produced per one gram of crude enzyme preparation over the long-term campaigns, indicating that EMR efficiently recovers enzyme activity.
Open AccessContinuous Production of Galacto-Oligosaccharides by an Enzyme Membrane Reactor Utilizing Free Enzymes
Galacto-oligosaccharides (GOS) are prebiotic compounds widely used for their health-promoting effects. Conventionally, GOS is produced by the enzymatic conversion of lactose in stirred tank reactors (STR). The high operational costs associated with enzyme inactivation and removal might be reduced by the application of enzyme membrane reactors (EMR). In this study, we aimed to assess the potential of continuous GOS production by EMR using soluble Biolacta N5, a Bacillus circulans-derived commercial enzyme preparation. The steady-state performance of the EMR equipped with an ultrafiltration module was investigated as function of residence time (1.1–2.8 h) and enzyme load (17–190 U·g−1) under fixed operational settings of temperature (50 °C), pH (6.0), lactose feed concentration (300 g·kg−1), and recirculation flow-rate (0.18 m3·h−1). Results indicate that the yield of oligosaccharides with higher degree of polymerization (DP3-6) in STR (approx. 38% on total carbohydrate basis) exceeds that measured in EMR (ranging from 24% to 33%). However, a stable catalytic performance without a significant deterioration in product quality was observed when operating the EMR for an extended period of time (>120 h). Approx. 1.4 kg of DP3-6 was produced per one gram of crude enzyme preparation over the long-term campaigns, indicating that EMR efficiently recovers enzyme activity.