Anita S. Smyshlyaeva
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Anita S. Smyshlyaeva has a total of 13 co-authors. Here are the top co-authors by number of shared publications:
- Aleksey A. Schulga
Research Centrum for Oncotheranostics, Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, 634050 Tomsk, Russia
1 shared publication - Alexander V. Lyubeshkin
Moscow State Academy of Fine Chemical Technology
1 shared publication - Alexey B. Kostyuk
Lobachevsky State University of Nizhni Novgorod-National Research University
1 shared publication - Andrei Vasilyevich Zvyagin
Scientific Center for Translational Medicine, Sirius University of Science and Technology, 354340 Sirius, Russia
1 shared publication - Elena V. Konovalova
Research Centrum for Oncotheranostics, Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, 634050 Tomsk, Russia
1 shared publication - Evgenii L. Guryev
Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarin Ave., 603022 Nizhny Novgorod, Russia
1 shared publication
Latest Publications
- Open Access
UCNP-based Photoluminescent Nanomedicines for Targeted Imaging and Theranostics of Cancer
Theranostic approach is currently among the fastest growing trends in cancer treatment. It implies the creation of multifunctional agents for simultaneous precise diagnosis and targeted impact on tumor cells. A new type of theranostic complexes was created based on NaYF4: Yb,Tm upconversion nanoparticles coated with polyethylene glycol and functionalized with the HER2-specific recombinant targeted toxin DARPin-LoPE. The obtained agents bind to HER2-overexpressing human breast adenocarcinoma cells and demonstrate selective cytotoxicity against this type of cancer cells. Using fluorescent human breast adenocarcinoma xenograft models, the possibility of intravital visualization of the UCNP-based complexes biodistribution and accumulation in tumor was demonstrated.
Open AccessUCNP-based Photoluminescent Nanomedicines for Targeted Imaging and Theranostics of Cancer
Theranostic approach is currently among the fastest growing trends in cancer treatment. It implies the creation of multifunctional agents for simultaneous precise diagnosis and targeted impact on tumor cells. A new type of theranostic complexes was created based on NaYF4: Yb,Tm upconversion nanoparticles coated with polyethylene glycol and functionalized with the HER2-specific recombinant targeted toxin DARPin-LoPE. The obtained agents bind to HER2-overexpressing human breast adenocarcinoma cells and demonstrate selective cytotoxicity against this type of cancer cells. Using fluorescent human breast adenocarcinoma xenograft models, the possibility of intravital visualization of the UCNP-based complexes biodistribution and accumulation in tumor was demonstrated.