César Gallo-Salazar
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
César Gallo-Salazar has a total of 31 co-authors. Here are the top co-authors by number of shared publications:
- Juan José Salinero
Sport Training Lab, Faculty of Sport Sciences, University of Castilla-La Mancha, 45071 Toledo, Spain
7 shared publications - Francisco Areces
Strength Training and Neuromuscular Performance Research Group (STreNgthP), C/Castillo de Alarcón, 49, Villanueva de la Cañada, 28692 Madrid, Spain
6 shared publications - Juan Del Coso
Institute of Health and Sport Sciences, Faculty of Health Sciences, Universidad Francisco de Vitoria, 28223 Madrid, Spain
6 shared publications - Beatriz Lara
GRUPO GIDECS, Exercise Physiology Laboratory, Faculty of Health Sciences-HM Hospitals, University Camilo José Cela, Villanueva de la Cañada, 49, 28692 Madrid, Spain
5 shared publications - Ester Jiménez-Ormeño
Strength Training and Neuromuscular Performance Research Group (STreNgthP_RG), Faculty of Health Sciences-HM Hospitals, University Camilo José Cela, Madrid, Spain; and
3 shared publications - Verónica Giráldez-Costas
GRUPO GIDECS, Exercise Physiology Laboratory, Faculty of Health Sciences-HM Hospitals, University Camilo José Cela, Villanueva de la Cañada, 49, 28692 Madrid, Spain
3 shared publications
Latest Publications
- Open Access
- 15 March 2026
- Published by MDPI AG in Journal of Functional Morphology and Kinesiology
- Vol. 11 (1) , 118
Neuromuscular Profile of CrossFit® Athletes: Part 1—Isometric and Ballistic Performance
Background: CrossFit® has gained widespread popularity as a high-intensity training modality, yet evidence describing neuromuscular performance characteristics in this population remains limited. This study aimed to evaluate isometric and ballistic strength profiles in trained CrossFit® athletes and to identify sex-based differences in absolute and relative neuromuscular performance. Methods: Seventy-two athletes participated (41 males and 31 females) participated in the study, completing two maximal isometric mid-thigh pull (IMTP) tests and three countermovement jump (CMJ) tests within a single testing session. Assessments were conducted using a dual force plate system (Hawkin Dynamics, Westbrook, ME, USA). Results: In the IMTP, males exhibited substantially higher absolute isometric force outputs, including peak force (3059 ± 576 vs. 1899 ± 324 N; p < 0.001) and relative peak force (36.34 ± 6.74 vs. 30.99 ± 4.41 N/kg; p < 0.001). Rates of force development were also greater in males for both early (0–50 ms: 7665 ± 5420 vs. 4001 ± 3021 N/s; p < 0.001) and late phases (0–250 ms: 5350 ± 1832 vs. 3035 ± 886 N/s; p < 0.001). However, no significant sex differences were detected in time to peak force (2.31 ± 1.27 vs. 1.94 ± 1.04 s) or dynamic strength index (0.72 ± 0.12 vs. 0.73 ± 0.12 a.u.). In ballistic performance using CMJ, males achieved higher jump height (0.33 ± 0.07 vs. 0.23 ± 0.05 m; p < 0.001), jump momentum (215 ± 27.9 vs. 131 ± 19.1 kg·m/s; p < 0.001), and modified reactive strength index (0.46 ± 0.11 vs. 0.32 ± 0.08 a.u.; p < 0.001). Relative propulsive and braking forces were also moderately greater in males. Notably, sex differences were reduced when variables were normalized to body mass or peak force, indicating comparable relative neuromuscular function across sexes. Conclusions: These findings provide descriptive neuromuscular performance data for CrossFit® athletes and show that sex-based differences primarily reflect disparities in absolute force-production capacity rather than intrinsic neuromuscular efficiency. Such insights may support more precise, evidence-informed, and sex-specific training prescriptions to optimize performance.
- 15 March 2026
- Published by MDPI AG in Journal of Functional Morphology and Kinesiology
- Vol. 11 (1) , 118
Open AccessNeuromuscular Profile of CrossFit® Athletes: Part 1—Isometric and Ballistic Performance
Background: CrossFit® has gained widespread popularity as a high-intensity training modality, yet evidence describing neuromuscular performance characteristics in this population remains limited. This study aimed to evaluate isometric and ballistic strength profiles in trained CrossFit® athletes and to identify sex-based differences in absolute and relative neuromuscular performance. Methods: Seventy-two athletes participated (41 males and 31 females) participated in the study, completing two maximal isometric mid-thigh pull (IMTP) tests and three countermovement jump (CMJ) tests within a single testing session. Assessments were conducted using a dual force plate system (Hawkin Dynamics, Westbrook, ME, USA). Results: In the IMTP, males exhibited substantially higher absolute isometric force outputs, including peak force (3059 ± 576 vs. 1899 ± 324 N; p < 0.001) and relative peak force (36.34 ± 6.74 vs. 30.99 ± 4.41 N/kg; p < 0.001). Rates of force development were also greater in males for both early (0–50 ms: 7665 ± 5420 vs. 4001 ± 3021 N/s; p < 0.001) and late phases (0–250 ms: 5350 ± 1832 vs. 3035 ± 886 N/s; p < 0.001). However, no significant sex differences were detected in time to peak force (2.31 ± 1.27 vs. 1.94 ± 1.04 s) or dynamic strength index (0.72 ± 0.12 vs. 0.73 ± 0.12 a.u.). In ballistic performance using CMJ, males achieved higher jump height (0.33 ± 0.07 vs. 0.23 ± 0.05 m; p < 0.001), jump momentum (215 ± 27.9 vs. 131 ± 19.1 kg·m/s; p < 0.001), and modified reactive strength index (0.46 ± 0.11 vs. 0.32 ± 0.08 a.u.; p < 0.001). Relative propulsive and braking forces were also moderately greater in males. Notably, sex differences were reduced when variables were normalized to body mass or peak force, indicating comparable relative neuromuscular function across sexes. Conclusions: These findings provide descriptive neuromuscular performance data for CrossFit® athletes and show that sex-based differences primarily reflect disparities in absolute force-production capacity rather than intrinsic neuromuscular efficiency. Such insights may support more precise, evidence-informed, and sex-specific training prescriptions to optimize performance.
- 4 July 2025
- Published by Taylor & Francis in International Journal of Performance Analysis in Sport
- Vol. 26 (3) , 657-666
Jump performance progression in Spanish male and female elite high and long jumpers
- 4 July 2025
- Published by Taylor & Francis in International Journal of Performance Analysis in Sport
- Vol. 26 (3) , 657-666
Jump performance progression in Spanish male and female elite high and long jumpers
- Open Access
Caffeine Enhances Some Aspects of Physical Performance in Well-Trained Hammer and Discus Throwers
Background: Caffeine is a widely recognized ergogenic aid for enhancing exercise performance. However, its effect on throwing performance has been less studied, yielding contradictory results. Objectives: The main aim of the study was to analyze the potential ergogenic effects of a moderate dose of caffeine (3 mg·kg−1 body mass) on vertical jump performance and throwing distance during a simulated competition in trained discus and hammer throwers. Methods: In a randomized, counterbalanced, and repeated measures design, 14 well-trained throwers (9 hammer throwers and 5 discus throwers; age 24.8 ± 6.3 years old, training 14.9 ± 5.0 h per week, competing experience 10.5 ± 6.1 years) performed a countermovement jump (CMJ) test, a modified throw, and a complete throw after the ingestion of 3 mg·kg⁻¹ body mass of caffeine or a placebo. Each participant performed three maximal-effort valid modified throws of his/her respective event (i.e., hammer or discus throw), plus three maximal-effort valid official throws (up to five tries, respectively, in case any attempt was called as foul). Throwing distance was measured according to World Athletics regulations using a metal tape, while release speed was assessed with a radar device. After the performance measurements, participants completed a form about side effects prevalence. Results: Caffeine, compared to placebo, increased throw distance (3.0 ± 5.1%, p = 0.048) and speed release (5.7 ± 8.7%, p = 0.03) for the complete throw, and distance (3.6 ± 4.4%, p = 0.01) and speed release (4.8 ± 7.4 %, p = 0.01) for the modified throw. Caffeine ingestion did not significantly improve jump height (1.1 ± 4.3%, p = 0.28), although it improved force and power on braking and the propulsive phases of the CMJ (p < 0.05). Caffeine only increased the prevalence of activeness (p < 0.05). Conclusions: An acute moderate dose of caffeine enhanced hammer and discus throw performance in well-trained throwers during a simulated competitive setting, with minimal adverse side effects.
Open AccessCaffeine Enhances Some Aspects of Physical Performance in Well-Trained Hammer and Discus Throwers
Background: Caffeine is a widely recognized ergogenic aid for enhancing exercise performance. However, its effect on throwing performance has been less studied, yielding contradictory results. Objectives: The main aim of the study was to analyze the potential ergogenic effects of a moderate dose of caffeine (3 mg·kg−1 body mass) on vertical jump performance and throwing distance during a simulated competition in trained discus and hammer throwers. Methods: In a randomized, counterbalanced, and repeated measures design, 14 well-trained throwers (9 hammer throwers and 5 discus throwers; age 24.8 ± 6.3 years old, training 14.9 ± 5.0 h per week, competing experience 10.5 ± 6.1 years) performed a countermovement jump (CMJ) test, a modified throw, and a complete throw after the ingestion of 3 mg·kg⁻¹ body mass of caffeine or a placebo. Each participant performed three maximal-effort valid modified throws of his/her respective event (i.e., hammer or discus throw), plus three maximal-effort valid official throws (up to five tries, respectively, in case any attempt was called as foul). Throwing distance was measured according to World Athletics regulations using a metal tape, while release speed was assessed with a radar device. After the performance measurements, participants completed a form about side effects prevalence. Results: Caffeine, compared to placebo, increased throw distance (3.0 ± 5.1%, p = 0.048) and speed release (5.7 ± 8.7%, p = 0.03) for the complete throw, and distance (3.6 ± 4.4%, p = 0.01) and speed release (4.8 ± 7.4 %, p = 0.01) for the modified throw. Caffeine ingestion did not significantly improve jump height (1.1 ± 4.3%, p = 0.28), although it improved force and power on braking and the propulsive phases of the CMJ (p < 0.05). Caffeine only increased the prevalence of activeness (p < 0.05). Conclusions: An acute moderate dose of caffeine enhanced hammer and discus throw performance in well-trained throwers during a simulated competitive setting, with minimal adverse side effects.
- 1 July 2024
- Published by Human Kinetics in International Journal of Sports Physiology and Performance
- Vol. 19 (7) , 629-636
“You Are Not Wrong About Getting Strong:” An Insight Into the Impact of Age Group and Level of Competition on Strength in Spanish Football Players
Objective: This study aimed to compare the maximum and rapid force production of Spanish football players and explore the differences between age group and level of competition. Methods: A cross-sectional study was developed to evaluate the peak force (PF), relative PF, and rate of force development over 250 ms (RFD0−250) during the isometric midthigh pull between groups of football players based on age group (senior vs junior) and level of competition (national vs regional). Using a portable isometric rig, 111 football players performed 2 isometric midthigh-pull trials on a force plate. Two-way analysis of variance with Bonferroni post hoc correction was applied, and statistical significance was set at P ≤ .05. The PF, relative PF, and RFD0−250 0, 25, 50, 75, and 100 percentiles were also calculated and descriptively reported, separated by age group and level of competition. Results: The analysis of variance revealed a significant main effect of the level of competition for the PF (P < .001), relative PF (P = .003), and RFD0−250 (P < .001). There was a significant main effect of age group for the PF (P < .001). There was a significant interaction effect of the age group × level of competition for relative PF (P = .014). National players were stronger than regional players on the PF and RFD0−250 (P < .001). Senior players were stronger than junior players for the PF (P < .001). Conclusions: Maximum and rapid force production are crucial for Spanish football players as they progress in both level of competition and age group. Practitioners should encourage young football players to prioritize strength development to improve their athletic performance.
- 1 July 2024
- Published by Human Kinetics in International Journal of Sports Physiology and Performance
- Vol. 19 (7) , 629-636
“You Are Not Wrong About Getting Strong:” An Insight Into the Impact of Age Group and Level of Competition on Strength in Spanish Football Players
Objective: This study aimed to compare the maximum and rapid force production of Spanish football players and explore the differences between age group and level of competition. Methods: A cross-sectional study was developed to evaluate the peak force (PF), relative PF, and rate of force development over 250 ms (RFD0−250) during the isometric midthigh pull between groups of football players based on age group (senior vs junior) and level of competition (national vs regional). Using a portable isometric rig, 111 football players performed 2 isometric midthigh-pull trials on a force plate. Two-way analysis of variance with Bonferroni post hoc correction was applied, and statistical significance was set at P ≤ .05. The PF, relative PF, and RFD0−250 0, 25, 50, 75, and 100 percentiles were also calculated and descriptively reported, separated by age group and level of competition. Results: The analysis of variance revealed a significant main effect of the level of competition for the PF (P < .001), relative PF (P = .003), and RFD0−250 (P < .001). There was a significant main effect of age group for the PF (P < .001). There was a significant interaction effect of the age group × level of competition for relative PF (P = .014). National players were stronger than regional players on the PF and RFD0−250 (P < .001). Senior players were stronger than junior players for the PF (P < .001). Conclusions: Maximum and rapid force production are crucial for Spanish football players as they progress in both level of competition and age group. Practitioners should encourage young football players to prioritize strength development to improve their athletic performance.
- Open Access
- 22 April 2024
- Published by MDPI AG in Healthcare
- Vol. 12 (8) , 866
The 8:1:1 Supplementation of Branched-Chain Amino Acids in High-Intensity Training: A Case Study of the Protective Effect on Rhabdomyolysis
Introduction: The increasing prevalence of high-intensity sports activities, notably the burgeoning popularity of CrossFit, underscores the contemporary significance of such physical pursuits. The discernible protective impact of branched-chain amino acids on muscle fatigue and injuries is emerging as a noteworthy area of investigation. Within the realm of sports, integrating BCAA supplementation into dietary practices holds promise for aiding athletes in their recovery, particularly in mitigating Delayed-Onset Muscle Soreness. Methodology: This study adopted an experimental pilot design with repeated measures, employing a controlled and randomized approach through double-blind procedures. The participant engaged in high-intensity activity, specifically the CrossFit Karen® test, which entailed executing 150 wall ball throws (9 kg) to a height of 3 m. The trial incorporated three randomized supplementation conditions: BCAAs in an 8:1:1 ratio or a 2:1:1 ratio or a placebo condition. The participant consumed 15 g daily for 7 days, commencing 72 h prior to the initial blood sample and the first Karen® test. Results: In this study, BCAA supplementation at an 8:1:1 ratio demonstrated a discernible protective effect against muscular damage, as evidenced by creatine kinase values and ratings of perceived exertion.
- 22 April 2024
- Published by MDPI AG in Healthcare
- Vol. 12 (8) , 866
Open AccessThe 8:1:1 Supplementation of Branched-Chain Amino Acids in High-Intensity Training: A Case Study of the Protective Effect on Rhabdomyolysis
Introduction: The increasing prevalence of high-intensity sports activities, notably the burgeoning popularity of CrossFit, underscores the contemporary significance of such physical pursuits. The discernible protective impact of branched-chain amino acids on muscle fatigue and injuries is emerging as a noteworthy area of investigation. Within the realm of sports, integrating BCAA supplementation into dietary practices holds promise for aiding athletes in their recovery, particularly in mitigating Delayed-Onset Muscle Soreness. Methodology: This study adopted an experimental pilot design with repeated measures, employing a controlled and randomized approach through double-blind procedures. The participant engaged in high-intensity activity, specifically the CrossFit Karen® test, which entailed executing 150 wall ball throws (9 kg) to a height of 3 m. The trial incorporated three randomized supplementation conditions: BCAAs in an 8:1:1 ratio or a 2:1:1 ratio or a placebo condition. The participant consumed 15 g daily for 7 days, commencing 72 h prior to the initial blood sample and the first Karen® test. Results: In this study, BCAA supplementation at an 8:1:1 ratio demonstrated a discernible protective effect against muscular damage, as evidenced by creatine kinase values and ratings of perceived exertion.
- Open Access
- 11 October 2023
- Published by Termedia Sp. z.o.o. in Journal of Human Kinetics
- Vol. 90 (1) , 161-168
Prospective and Retrospective Analysis of the Sporting Success of Elite Spanish High and Long Jumpers
The aim of the present study was to analyze the sporting progression from U14 to senior categories of elite Spanish high and long jumpers. For prospective analysis, 300 athletes ranked top 20 at U14 were analyzed (153 female and 147 male). For retrospective analysis, 64 athletes ranked in the top...
- 11 October 2023
- Published by Termedia Sp. z.o.o. in Journal of Human Kinetics
- Vol. 90 (1) , 161-168
Open AccessProspective and Retrospective Analysis of the Sporting Success of Elite Spanish High and Long Jumpers
The aim of the present study was to analyze the sporting progression from U14 to senior categories of elite Spanish high and long jumpers. For prospective analysis, 300 athletes ranked top 20 at U14 were analyzed (153 female and 147 male). For retrospective analysis, 64 athletes ranked in the top...
- Open Access
- 1 October 2020
- Published by FapUNIFESP (SciELO) in Revista Brasileira de Medicina do Esporte
- Vol. 26 (5) , 391-395
THICKNESS AND CROSS-SECTIONAL AREA OF THE ACHILLES TENDON IN MARATHON RUNNERS: A CROSS-SECTIONAL STUDY
Introduction: This study aimed to measure thickness and cross-sectional area of the Achilles tendon (AT), and the range of motion of the ankle joint in dorsiflexion of amateur marathon runners compared to non-active people. Objectives: To analyze the relationship between cross-sectional area and thickness of the Achilles tendon in marathon runners and age, anthropometric characteristics (height and body mass), training habits, running experience, marathon performance, and range of motion in the ankle joint. Methods: Achilles tendon thickness and cross-sectional area were measured using ultrasound images of the left leg in 97 male amateur marathon runners (age 42.0 ± 9.6 years; height 175 ± 6 cm; and body mass 73.7 ± 8.6 kg), and 47 controls (39.9 ± 11.6 years; 176 ± 7 cm; 79.6 ± 16.1 kg). Results: Achilles tendon thickness (4.81 ± 0.77 vs. 4.60 ± 0.66 mm; p = 0.01) and cross-sectional area (60.41 ± 14.36 vs. 53.62 ± 9.90 mm2; p < 0.01) were greater in the marathon runners than in non-active people. Achilles tendon thickness has been correlated, in a weak but significant manner, with years of running experience. Moreover, marathon runners showed increased ankle range of motion (81.81 ± 6.93 vs. 77.86 ± 7.27 grades; p<0.01). Conclusion: Male amateur marathon runners have hypertrophy of the Achilles tendon compared to non-active people, and this enlargement is mediated by running experience. In addition, range of motion in ankle dorsiflexion is favored by marathon training. Level of evidence III; Retrospective study.
- 1 October 2020
- Published by FapUNIFESP (SciELO) in Revista Brasileira de Medicina do Esporte
- Vol. 26 (5) , 391-395
Open AccessTHICKNESS AND CROSS-SECTIONAL AREA OF THE ACHILLES TENDON IN MARATHON RUNNERS: A CROSS-SECTIONAL STUDY
Introduction: This study aimed to measure thickness and cross-sectional area of the Achilles tendon (AT), and the range of motion of the ankle joint in dorsiflexion of amateur marathon runners compared to non-active people. Objectives: To analyze the relationship between cross-sectional area and thickness of the Achilles tendon in marathon runners and age, anthropometric characteristics (height and body mass), training habits, running experience, marathon performance, and range of motion in the ankle joint. Methods: Achilles tendon thickness and cross-sectional area were measured using ultrasound images of the left leg in 97 male amateur marathon runners (age 42.0 ± 9.6 years; height 175 ± 6 cm; and body mass 73.7 ± 8.6 kg), and 47 controls (39.9 ± 11.6 years; 176 ± 7 cm; 79.6 ± 16.1 kg). Results: Achilles tendon thickness (4.81 ± 0.77 vs. 4.60 ± 0.66 mm; p = 0.01) and cross-sectional area (60.41 ± 14.36 vs. 53.62 ± 9.90 mm2; p < 0.01) were greater in the marathon runners than in non-active people. Achilles tendon thickness has been correlated, in a weak but significant manner, with years of running experience. Moreover, marathon runners showed increased ankle range of motion (81.81 ± 6.93 vs. 77.86 ± 7.27 grades; p<0.01). Conclusion: Male amateur marathon runners have hypertrophy of the Achilles tendon compared to non-active people, and this enlargement is mediated by running experience. In addition, range of motion in ankle dorsiflexion is favored by marathon training. Level of evidence III; Retrospective study.
- 1 August 2019
- Published by Human Kinetics in International Journal of Sports Physiology and Performance
- Vol. 14 (7) , 887-893
Game Activity and Physiological Responses of Young Tennis Players in a Competition With 2 Consecutive Matches in a Day
Purpose: To determine whether the game activity and physiological responses of young tennis players differed depending on the session of play (eg, morning [MOR] vs afternoon [AFT]) and the final match outcome (eg, winners vs losers) during a simulated competition with 2 matches on the same day. Methods: A total of 12 well-trained male tennis players (age 14.5 [0.8] y) took part in a simulated competition of two 3-set matches separated by 3 h. All the matches were video recorded, and the participants were monitored using 10-Hz global positioning system units including a heart-rate monitor. Effect-size (ES) statistics were used to investigate the magnitudes of the differences. Results: During the AFT matches, in absolute terms, players covered longer total distance (ES = moderate) and ran more distance between 0 and ≤4 m·s−1 (ES = small to large) than in MOR matches. Total duration was also longer (ES = large) in the AFT, where the rest time between rallies was also longer (ES = very large). Heart rate was similar during AFT and MOR matches, but higher rates of perceived exertion (ES = moderate) were reported in the AFT. Only peak running velocity was observed to be likely higher for losers than for winners (ES = small). Conclusions: Game activity and physiological responses of young tennis players differ when 2 consecutive matches are played on the same day. These data might help elucidate the need for specific precompetition training loads and/or between-matches/sessions recovery strategies when facing overloaded competitions.
- 1 August 2019
- Published by Human Kinetics in International Journal of Sports Physiology and Performance
- Vol. 14 (7) , 887-893
Game Activity and Physiological Responses of Young Tennis Players in a Competition With 2 Consecutive Matches in a Day
Purpose: To determine whether the game activity and physiological responses of young tennis players differed depending on the session of play (eg, morning [MOR] vs afternoon [AFT]) and the final match outcome (eg, winners vs losers) during a simulated competition with 2 matches on the same day. Methods: A total of 12 well-trained male tennis players (age 14.5 [0.8] y) took part in a simulated competition of two 3-set matches separated by 3 h. All the matches were video recorded, and the participants were monitored using 10-Hz global positioning system units including a heart-rate monitor. Effect-size (ES) statistics were used to investigate the magnitudes of the differences. Results: During the AFT matches, in absolute terms, players covered longer total distance (ES = moderate) and ran more distance between 0 and ≤4 m·s−1 (ES = small to large) than in MOR matches. Total duration was also longer (ES = large) in the AFT, where the rest time between rallies was also longer (ES = very large). Heart rate was similar during AFT and MOR matches, but higher rates of perceived exertion (ES = moderate) were reported in the AFT. Only peak running velocity was observed to be likely higher for losers than for winners (ES = small). Conclusions: Game activity and physiological responses of young tennis players differ when 2 consecutive matches are played on the same day. These data might help elucidate the need for specific precompetition training loads and/or between-matches/sessions recovery strategies when facing overloaded competitions.
- Open Access
CYP1A2 Genotype Variations Do Not Modify the Benefits and Drawbacks of Caffeine during Exercise: A Pilot Study
Previous investigations have determined that some individuals have minimal or even ergolytic performance effects after caffeine ingestion. The aim of this study was to analyze the influence of the genetic variations of the CYP1A2 gene on the performance enhancement effects of ingesting a moderate dose of caffeine. In a double-blind randomized experimental design, 21 healthy active participants (29.3 ± 7.7 years) ingested 3 mg of caffeine per kg of body mass or a placebo in testing sessions separated by one week. Performance in the 30 s Wingate test, visual attention, and side effects were evaluated. DNA was obtained from whole blood samples and the CYP1A2 polymorphism was analyzed (rs762551). We obtained two groups: AA homozygotes (n = 5) and C-allele carriers (n = 16). Caffeine ingestion increased peak power (682 ± 140 vs. 667 ± 137 W; p = 0.008) and mean power during the Wingate test (527 ± 111 vs. 518 ± 111 W; p < 0.001) with no differences between AA homozygotes and C-allele carriers (p > 0.05). Reaction times were similar between caffeine and placebo conditions (276 ± 31 vs. 269 ± 71 milliseconds; p = 0.681) with no differences between AA homozygotes and C-allele carriers. However, 31.3% of the C-allele carriers reported increased nervousness after caffeine ingestion, while none of the AA homozygotes perceived this side effect. Genetic variations of the CYP1A2 polymorphism did not affect the ergogenic effects and drawbacks derived from the ingestion of a moderate dose of caffeine.
Open AccessCYP1A2 Genotype Variations Do Not Modify the Benefits and Drawbacks of Caffeine during Exercise: A Pilot Study
Previous investigations have determined that some individuals have minimal or even ergolytic performance effects after caffeine ingestion. The aim of this study was to analyze the influence of the genetic variations of the CYP1A2 gene on the performance enhancement effects of ingesting a moderate dose of caffeine. In a double-blind randomized experimental design, 21 healthy active participants (29.3 ± 7.7 years) ingested 3 mg of caffeine per kg of body mass or a placebo in testing sessions separated by one week. Performance in the 30 s Wingate test, visual attention, and side effects were evaluated. DNA was obtained from whole blood samples and the CYP1A2 polymorphism was analyzed (rs762551). We obtained two groups: AA homozygotes (n = 5) and C-allele carriers (n = 16). Caffeine ingestion increased peak power (682 ± 140 vs. 667 ± 137 W; p = 0.008) and mean power during the Wingate test (527 ± 111 vs. 518 ± 111 W; p < 0.001) with no differences between AA homozygotes and C-allele carriers (p > 0.05). Reaction times were similar between caffeine and placebo conditions (276 ± 31 vs. 269 ± 71 milliseconds; p = 0.681) with no differences between AA homozygotes and C-allele carriers. However, 31.3% of the C-allele carriers reported increased nervousness after caffeine ingestion, while none of the AA homozygotes perceived this side effect. Genetic variations of the CYP1A2 polymorphism did not affect the ergogenic effects and drawbacks derived from the ingestion of a moderate dose of caffeine.
- 2 February 2016
- Vol. 56 (12) , 1433-1438
Respiratory function is associated to marathon race time.
The purpose of this study was to analyze the relationship between marathon race time and expiratory pulmonary parameters in a heterogeneous group of amateur marathoners. A total of 110 marathon runners (age=41.9±9.4 yr, body mass=74.0±9.1 kg, height=175.0±8.0 cm) volunteered to participate in this study. First, they completed a questionnaire about running experience and best performance time in the 10-km, half-marathon and marathon competitions. Then, they performed a maximal spirometry test following guidelines for standardized spirometry. Measurement included peak expiratory flow (PEF), forced expiratory volume in the first second (FEV1) and forced vital capacity (FVC). All these expiratory variables were normalized for the participant's body mass. Within 3 days of the spirometry test, participants competed in an official marathon and race time was measured by a chip-timing. After this, participants were grouped by their marathon race time as follows: 240 min, N.=46). Marathon race time correlated to the FVC·kg-1 (r=-0.41; P0.05). The group of faster marathoners (e.g., 240 min group: 0.057±0.009; P240 min group: 0.072±0.010; P<0.001) than the other two groups of slower runners. These results suggest a significant relationship between individual pulmonary function and marathon race time. Thus, a higher lung capacity per kg of body mass might be a key variable for marathon performance in amateur runners.
- 2 February 2016
- Vol. 56 (12) , 1433-1438
Respiratory function is associated to marathon race time.
The purpose of this study was to analyze the relationship between marathon race time and expiratory pulmonary parameters in a heterogeneous group of amateur marathoners. A total of 110 marathon runners (age=41.9±9.4 yr, body mass=74.0±9.1 kg, height=175.0±8.0 cm) volunteered to participate in this study. First, they completed a questionnaire about running experience and best performance time in the 10-km, half-marathon and marathon competitions. Then, they performed a maximal spirometry test following guidelines for standardized spirometry. Measurement included peak expiratory flow (PEF), forced expiratory volume in the first second (FEV1) and forced vital capacity (FVC). All these expiratory variables were normalized for the participant's body mass. Within 3 days of the spirometry test, participants competed in an official marathon and race time was measured by a chip-timing. After this, participants were grouped by their marathon race time as follows: 240 min, N.=46). Marathon race time correlated to the FVC·kg-1 (r=-0.41; P0.05). The group of faster marathoners (e.g., 240 min group: 0.057±0.009; P240 min group: 0.072±0.010; P<0.001) than the other two groups of slower runners. These results suggest a significant relationship between individual pulmonary function and marathon race time. Thus, a higher lung capacity per kg of body mass might be a key variable for marathon performance in amateur runners.