Jiehang Deng

Cancer is a complex and heterogeneous disease, where even patients with the same cancer type may respond differently to treatment regimens. Predicting the therapeutic effects of drugs on cancer based on cancer characteristics is a critical aspect of precision oncology. Currently, most anticancer drug response(CDR) prediction methods rely on extracting features from the cell line-drug bipartite composition. However, these methods often fail to adequately capture the features of both drugs and cell lines, ignoring the homogeneous features of cell lines and drugs and their correlation with deep heterogeneous features. To address these challenges, we propose a novel prediction framework that leverages a heterogeneous and homogeneous hybrid graph neural network named H $ ^{3}$ CDR. H $ ^{3}$ CDR learns the similarity features of cancer cell lines and drugs by fusing their multi-omics data. Additionally, a multi-branch network is employed to extract features from both cell lines and drugs, enabling the identification of potential features. Extensive experiments on the GDSC and CCLE databases demonstrate the superiority of our model. Evaluated by five-fold cross-validation, H $ ^{3}$ CDR achieves an area under the ROC curve (AUC) of 0.8772 and an area under the precision-recall curve (AUPRC) of 0.8819 on the GDSC dataset.

Accurate, reliable, and fast intelligent detection of leather surface defects has become an important subject in industrial inspection, which aims at improving production efficiency and increasing automation levels. This work focuses on the rapid defect recognition and localization of leather surface defects for industrious applications, which is based on the state-of-the-art real-time detection model YOLO. Three experimental Schemes with different challenges were designed to find the optimal YOLO-based leather surface defect detection scheme. Typical tanned leather surface defect images from the factory were collected, which are comprised of eight types of defects, namely rotten surface, hole, scratch, crease, healed injury, bacterial injury, growth line, and pinhole, which exhibit variations in shapes, sizes, and colors, reflecting the various characteristics found in tanned leather defects. A comprehensive and in-depth review of the YOLO series of models is presented, including YOLOv1 to YOLOv8. The systematic and extensive experiments indicate that the YOLO models can simultaneously detect multiple types of defects present in each leather image. The multi-defect detection task achieved a maximum of 52.3% mean average precision (mAP), 58.2% precision, and 68.7% recall. For single-class detection tasks, the highest performance reached 85.1% mAP, 90.9% precision, and 81.8% recall. These works provide feasible intelligent solutions for surface defects in the leather industry, laying a solid foundation for the design and development of new solutions for leather defect detection.

Automatic license plate recognition (ALPR) system has been widely used in intelligent transportation and other fields. However, in complex environments such as vehicle sound source localization, poor illumination, or bad weather conditions, ALPR is still a challenging problem. Aiming at the problem, an end-to-end deep learning framework is developed based on depthwise over-parameterized convolution recurrent neural network for license plate character recognition. The proposed framework is composed as follows: (i) license plate correcting module based on spatial transformation network; (ii) feature extraction module based on depthwise over-parameterized convolution; (iii) sequence annotation module based on bidirectional long short-term memory; and (iv) regularized sequence decoding module based on connectionist temporal classification with maximum conditional entropy. Two open-source datasets of Chinese License Plate Datasets (SYSU) and Chinese City Parking Dataset (CCPD) are used to verify the performance of the algorithm. The proposed end-to-end framework can effectively rectify distorted and inclined license plates in spatial domain. It can recognize license plates without complex character segmentation process. Compared with some current state-of-art algorithms, the proposed algorithm achieved the best performance with the recognition accuracy of 96.31% and 88.31% based on the two datasets of SYSU and CCPD, respectively.

Machine-vision-based surface defect inspection is one of the key technologies to realize intelligent manufacturing. This paper provides a systematic review on leather surface defect inspections based on machine vision. Leather products are regarded as the most traded products all over the world. Automatic detection, location, and recognition of leather surface defects are very important for the intelligent manufacturing of leather products, and are challenging but noteworthy tasks. This work investigates a large amount of literature related to leather surface defect inspection. In addition, we also investigate and evaluate the performance of some edge detectors and threshold detectors for leather defect detection, and the identification accuracy of the classical machine learning method SVM for leather surface defect identification. A detailed and methodical review of leather surface defect inspection with image analysis and machine learning is presented. Main challenges and future development trends are discussed for leather surface defect inspection, which can be used as a source of guidelines for designing and developing new solutions in this field.