Kwang-Ho Kim
Research Subjects
Research Interests
Kwang-Ho Kim has a total of 6 co-authors. Here are the top co-authors by number of shared publications:
- Chun-Sik Bae
College of Veterinary Medicine, Chonnam National University, Gwangju 61186, Korea
1 shared publication - Dae-Hun Park
College of Oriental Medicine, Dongshin University, Naju-si 58245, Republic of Korea
1 shared publication - Min-Hee Kim
College of Oriental Medicine, Dongshin University, Naju 58245, Republic of Korea
1 shared publication - Min-Jae Lee
Kangwon National University
1 shared publication - So-Hyeon Bok
College of Oriental Medicine, Dongshin University, Naju 58245, Republic of Korea
1 shared publication - Soon-Young Lee
Bio-Medicine Advanced Formulation Research Center, RLRC, Mokpo National University, Muan 58554, Republic of Korea
1 shared publication
Latest Publications
- Open Access
Bactericidal and Virucidal Efficacies and Safety of Puriton®
In 2016, infectious microbes were one of the leading causes of death, especially in developing countries. Puriton® is a mineral mixture consisting of biotite, kaolinite, montmorillonite, serpentine, clinochlore, and vermiculite, and evaluated antimicrobial activity in vitro and safety in vivo. Nine pathogens and opportunistic bacteria, namely Salmonella typhimurium, Escherichia coli, Pseudomonas aeruginosa, Alcaligenes faecalis, Staphylococcus aureus, Enterococcus faecalis, Micrococcus luteus, Mycobacterium smegmatis, and Bacillus subtilis, and the two viruses Zika and Influenza A/Duck/MN/1525/81 were used. A 26-week oral repeated safety study of Puriton® was conducted. Puriton® suppressed the bacterial proliferation, with a minimum proliferative rate of 91.1% in B. subtilis ATCC6633. The virucidal efficacy of Puriton® against Zika virus after 4 h and 18 h of contact time was significant in all groups treated with Puriton®. Twenty-six-week repeated oral administration of Puriton® was considered safe based on physiological results, such as behavior and blood cells/chemistry, and histopathological changes in the brain, heart, kidney, liver, and lung. We concluded that Puriton® exerted bactericidal and virucidal efficacies and was safe for 26-week repeated oral administration.
Open AccessBactericidal and Virucidal Efficacies and Safety of Puriton®
In 2016, infectious microbes were one of the leading causes of death, especially in developing countries. Puriton® is a mineral mixture consisting of biotite, kaolinite, montmorillonite, serpentine, clinochlore, and vermiculite, and evaluated antimicrobial activity in vitro and safety in vivo. Nine pathogens and opportunistic bacteria, namely Salmonella typhimurium, Escherichia coli, Pseudomonas aeruginosa, Alcaligenes faecalis, Staphylococcus aureus, Enterococcus faecalis, Micrococcus luteus, Mycobacterium smegmatis, and Bacillus subtilis, and the two viruses Zika and Influenza A/Duck/MN/1525/81 were used. A 26-week oral repeated safety study of Puriton® was conducted. Puriton® suppressed the bacterial proliferation, with a minimum proliferative rate of 91.1% in B. subtilis ATCC6633. The virucidal efficacy of Puriton® against Zika virus after 4 h and 18 h of contact time was significant in all groups treated with Puriton®. Twenty-six-week repeated oral administration of Puriton® was considered safe based on physiological results, such as behavior and blood cells/chemistry, and histopathological changes in the brain, heart, kidney, liver, and lung. We concluded that Puriton® exerted bactericidal and virucidal efficacies and was safe for 26-week repeated oral administration.