Jacob Simmonds
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Previous Organizations / Institutes
The organizations / institutes from the scholar's other articles in the past ten years
Research Subjects
Jacob Simmonds has a total of 23 co-authors. Here are the top co-authors by number of shared publications:
- Yevgeny Raitses
Princeton Plasma Physics Laboratory
4 shared publications - Andrei Smolyakov
University of Saskatchewan
3 shared publications - Anupama Rao
Departments of Pediatric Hematology (A.R., J.B.)
2 shared publications - Arina Lazareva
Great Ormond Street Hospital for Children NHS Trust 3 , London
2 shared publications - Austen Worth
Great Ormond Street Hospital for Children, 5 Department of Immunology and Gene Therapy, London
2 shared publications - Charlotte Jane Houldcroft
Department of Genetics, University of Cambridge
2 shared publications
Latest Publications
- Open Access
- 1 February 2024
- Published by AIP Publishing in Review of Scientific Instruments
- Vol. 95 (2)
Xenon tracers for cost effective laser induced fluorescence of alternative propellant Hall thrusters
One of the limiting factors to developing plasma thrusters on alternative propellants is the cost associated with changing the diagnostic tools, which are often propellant-dependent. For laser induced fluorescence (LIF), which is typically used for ion velocity distribution measurements to determine ion trajectories and potential profiles, either new lasers need to be bought, which are tuned to the wavelength of the new element’s excitation level, or a costly tunable laser is required. A method to use existing LIF setups designed for xenon on any propellant has been demonstrated on a Hall thruster operating on krypton. In the demonstration test, a small amount of xenon (0.01%–4%) was mixed with the main krypton propellant for use as a diagnostic tracer, and xenon ion velocities were measured while also monitoring changes in the mean discharge current and oscillations. High signal-to-noise ratios in LIF data acquired along the channel centerline were obtained with tracer gas fractions ≤1% that negligibly affected the thruster operation. These results and comparison of the emission spectra of xenon and other common propellants suggest that the tracer LIF method should be broadly applicable to LIF measurements in Hall thrusters operating on alternative propellants.
- 1 February 2024
- Published by AIP Publishing in Review of Scientific Instruments
- Vol. 95 (2)
Open AccessXenon tracers for cost effective laser induced fluorescence of alternative propellant Hall thrusters
One of the limiting factors to developing plasma thrusters on alternative propellants is the cost associated with changing the diagnostic tools, which are often propellant-dependent. For laser induced fluorescence (LIF), which is typically used for ion velocity distribution measurements to determine ion trajectories and potential profiles, either new lasers need to be bought, which are tuned to the wavelength of the new element’s excitation level, or a costly tunable laser is required. A method to use existing LIF setups designed for xenon on any propellant has been demonstrated on a Hall thruster operating on krypton. In the demonstration test, a small amount of xenon (0.01%–4%) was mixed with the main krypton propellant for use as a diagnostic tracer, and xenon ion velocities were measured while also monitoring changes in the mean discharge current and oscillations. High signal-to-noise ratios in LIF data acquired along the channel centerline were obtained with tracer gas fractions ≤1% that negligibly affected the thruster operation. These results and comparison of the emission spectra of xenon and other common propellants suggest that the tracer LIF method should be broadly applicable to LIF measurements in Hall thrusters operating on alternative propellants.
- Open Access
- 30 March 2023
- Published by Springer Nature in Journal of Electric Propulsion
- Vol. 2 (1) , 1-26
A theoretical thrust density limit for Hall thrusters
Hall Thrusters typically operate at thrust densities on the order of 10 N/m $$^2$$ , which appear to be orders of magnitude below the thrust density limits suggested in previous literature. These limits have been considered here and each component of thrust density is analyzed to demonstrate the relative contribution to the total thrust density. Dependencies of the thrust density limits upon the thruster geometry, electron mobility, and the applied magnetic field are revealed and compared with experimental measurements of thrust density. This analysis reveals that with conventional applied magnetic field strengths, Hall thruster thrust density appears to be on the order of 1000 N/m $$^2$$ . It is shown that this limit can be further increased through higher applied magnetic fields, applied voltage, and suppression of anomalous electron transport. This suggests Hall thrusters can be made much more compact and operated at higher power densities, given improvements to the thermal management and materials.- 30 March 2023
- Published by Springer Nature in Journal of Electric Propulsion
- Vol. 2 (1) , 1-26
Open AccessA theoretical thrust density limit for Hall thrusters
Hall Thrusters typically operate at thrust densities on the order of 10 N/m $$^2$$ , which appear to be orders of magnitude below the thrust density limits suggested in previous literature. These limits have been considered here and each component of thrust density is analyzed to demonstrate the relative contribution to the total thrust density. Dependencies of the thrust density limits upon the thruster geometry, electron mobility, and the applied magnetic field are revealed and compared with experimental measurements of thrust density. This analysis reveals that with conventional applied magnetic field strengths, Hall thruster thrust density appears to be on the order of 1000 N/m $$^2$$ . It is shown that this limit can be further increased through higher applied magnetic fields, applied voltage, and suppression of anomalous electron transport. This suggests Hall thrusters can be made much more compact and operated at higher power densities, given improvements to the thermal management and materials. - Open Access
A Theoretical Thrust Density Limit for Hall Thrusters
Hall Thrusters typically operate at thrust densities on the order of 10 N/m2, which is well below the thrust density limits discussed in previous literature. These limits have been considered here and each component of thrust density is analyzed to demonstrate the relative contribution to the total thrust density. Dependencies of the thrust density limits upon the thruster geometry, electron mobility, and the applied magnetic field are revealed and compared with experimental data.
Open AccessA Theoretical Thrust Density Limit for Hall Thrusters
Hall Thrusters typically operate at thrust densities on the order of 10 N/m2, which is well below the thrust density limits discussed in previous literature. These limits have been considered here and each component of thrust density is analyzed to demonstrate the relative contribution to the total thrust density. Dependencies of the thrust density limits upon the thruster geometry, electron mobility, and the applied magnetic field are revealed and compared with experimental data.
- 22 November 2021
- Published by AIP Publishing in Applied Physics Letters
- Vol. 119 (21) , 213501
Mitigation of breathing oscillations and focusing of the plume in a segmented electrode wall-less Hall thruster
In the absence of the channel walls bounding the plasma, a wall-less Hall thruster is a promising configuration with a potentially longer lifetime and easier scalability than conventional Hall thrusters. Because the ion acceleration takes place in the fringing magnetic field with a strong axial component, the operation of a typical wall-less thruster is characterized by a large beam divergence of the plasma flow, which reduces the thrust. In this work, the addition of a biased segmented electrode to the wall-less thruster is shown to significantly narrow the plasma plume and suppress large amplitude breathing oscillations of the discharge current commonly associated with ionization instability. Both effects result in improvements to the thruster performance. Physical mechanisms responsible for these effects are unclear, but they are apparently associated with the reduction of the electron cross field transport to the anode and a transition in the breathing mode frequency.
- 22 November 2021
- Published by AIP Publishing in Applied Physics Letters
- Vol. 119 (21) , 213501
Mitigation of breathing oscillations and focusing of the plume in a segmented electrode wall-less Hall thruster
In the absence of the channel walls bounding the plasma, a wall-less Hall thruster is a promising configuration with a potentially longer lifetime and easier scalability than conventional Hall thrusters. Because the ion acceleration takes place in the fringing magnetic field with a strong axial component, the operation of a typical wall-less thruster is characterized by a large beam divergence of the plasma flow, which reduces the thrust. In this work, the addition of a biased segmented electrode to the wall-less thruster is shown to significantly narrow the plasma plume and suppress large amplitude breathing oscillations of the discharge current commonly associated with ionization instability. Both effects result in improvements to the thruster performance. Physical mechanisms responsible for these effects are unclear, but they are apparently associated with the reduction of the electron cross field transport to the anode and a transition in the breathing mode frequency.
- 1 October 2021
- Published by AIP Publishing in Physics of Plasmas
- Vol. 28 (10) , 102510
Evolution of electron cross-field transport induced by an equilibrium azimuthal electric field in an E × B Hall thruster discharge under an azimuthally inhomogeneous neutral supply
The electron cross field transport by the induced azimuthal electric field in a Hall thruster exhibits the mobility scaled by 1/B. This study investigates parameters affecting this transport over a Hall thruster's distinct regions, such as the ionization, acceleration, and plume regions. The main focus is on the nonzero equilibrium azimuthal electric field induced by an azimuthally inhomogeneous neutral supply. A fast Fourier transform analysis of the plasma structure reveals that the wavenumber k of the azimuthal plasma structure increases from k = 2, which is the input condition, to k = 4 in the plume region, and that the total axial flux caused by the azimuthal electric field is mainly induced from the structures of the dominant Fourier components. The azimuthal phase relation between plasma potential and density is formed to maximize the axial electron flux at the plume region and starts varying along with other plasma properties as electrons flow toward the acceleration region. The spatial evolution of the effective axial mobility coefficient is extracted, and its regional characteristics are discussed.
- 1 October 2021
- Published by AIP Publishing in Physics of Plasmas
- Vol. 28 (10) , 102510
Evolution of electron cross-field transport induced by an equilibrium azimuthal electric field in an E × B Hall thruster discharge under an azimuthally inhomogeneous neutral supply
The electron cross field transport by the induced azimuthal electric field in a Hall thruster exhibits the mobility scaled by 1/B. This study investigates parameters affecting this transport over a Hall thruster's distinct regions, such as the ionization, acceleration, and plume regions. The main focus is on the nonzero equilibrium azimuthal electric field induced by an azimuthally inhomogeneous neutral supply. A fast Fourier transform analysis of the plasma structure reveals that the wavenumber k of the azimuthal plasma structure increases from k = 2, which is the input condition, to k = 4 in the plume region, and that the total axial flux caused by the azimuthal electric field is mainly induced from the structures of the dominant Fourier components. The azimuthal phase relation between plasma potential and density is formed to maximize the axial electron flux at the plume region and starts varying along with other plasma properties as electrons flow toward the acceleration region. The spatial evolution of the effective axial mobility coefficient is extracted, and its regional characteristics are discussed.
- 2 September 2021
- Published by AIP Publishing in Journal of Applied Physics
- Vol. 130 (9) , 093302
Ion acceleration in a wall-less Hall thruster
In wall-less Hall thrusters, the ionization of the propellant and the acceleration of the ions occur outside the thruster [S. Mazouffre, S. Tsikata, and J. Vaudolon, in 50th AIAA/ASME/SAE/ASEE Joint Propulsion Conference (American Institute of Aeronautics and Astronautics, Cleveland, OH, 2014)]. This reduces interactions between the plasma and the thruster parts as compared to conventional annular and cylindrical Hall thrusters and promises a longer thruster lifetime. With a much simpler design, these non-conventional thrusters are also easier to miniaturize for operation at low power levels of a few hundred watts and lower. In this work, experiments demonstrate that a miniaturized (3 cm diameter) 200 W wall-less thruster is also able to achieve similar voltage utilization, propellant utilization, and current utilization efficiencies as conventional Hall thrusters. Yet, thruster performance of the wall-less thruster is generally lower due to a much larger plume divergence than that in conventional Hall thrusters. This plume divergence is a consequence of ion acceleration in the fringing magnetic field. Thrust and plasma measurements suggest that the thrust generated by the wall-less thruster is due to two components: ion acceleration by the JxB force in the region of the fringing magnetic field radially away from the thruster and by plasma expansion in the diverging magnetic field near the thruster axis.
- 2 September 2021
- Published by AIP Publishing in Journal of Applied Physics
- Vol. 130 (9) , 093302
Ion acceleration in a wall-less Hall thruster
In wall-less Hall thrusters, the ionization of the propellant and the acceleration of the ions occur outside the thruster [S. Mazouffre, S. Tsikata, and J. Vaudolon, in 50th AIAA/ASME/SAE/ASEE Joint Propulsion Conference (American Institute of Aeronautics and Astronautics, Cleveland, OH, 2014)]. This reduces interactions between the plasma and the thruster parts as compared to conventional annular and cylindrical Hall thrusters and promises a longer thruster lifetime. With a much simpler design, these non-conventional thrusters are also easier to miniaturize for operation at low power levels of a few hundred watts and lower. In this work, experiments demonstrate that a miniaturized (3 cm diameter) 200 W wall-less thruster is also able to achieve similar voltage utilization, propellant utilization, and current utilization efficiencies as conventional Hall thrusters. Yet, thruster performance of the wall-less thruster is generally lower due to a much larger plume divergence than that in conventional Hall thrusters. This plume divergence is a consequence of ion acceleration in the fringing magnetic field. Thrust and plasma measurements suggest that the thrust generated by the wall-less thruster is due to two components: ion acceleration by the JxB force in the region of the fringing magnetic field radially away from the thruster and by plasma expansion in the diverging magnetic field near the thruster axis.
- Open Access
- 24 August 2021
- Published by Wiley in British Journal of Haematology
- Vol. 195 (2) , 249-255
Epstein–Barr virus (EBV) deletions as biomarkers of response to treatment of chronic active EBV
Summary: Chronic active Epstein–Barr virus (CAEBV) disease is a rare condition characterised by persistent EBV infection in previously healthy individuals. Defective EBV genomes were found in East Asian patients with CAEBV. In the present study, we sequenced 14 blood EBV samples from three UK patients with CAEBV, comparing the results with saliva CAEBV samples and other conditions. We observed EBV deletions in blood, some of which may disrupt viral replication, but not saliva in CAEBV. Deletions were lost overtime after successful treatment. These findings are compatible with CAEBV being associated with the evolution and persistence of EBV+ haematological clones that are lost on successful treatment.
- 24 August 2021
- Published by Wiley in British Journal of Haematology
- Vol. 195 (2) , 249-255
Open AccessEpstein–Barr virus (EBV) deletions as biomarkers of response to treatment of chronic active EBV
Summary: Chronic active Epstein–Barr virus (CAEBV) disease is a rare condition characterised by persistent EBV infection in previously healthy individuals. Defective EBV genomes were found in East Asian patients with CAEBV. In the present study, we sequenced 14 blood EBV samples from three UK patients with CAEBV, comparing the results with saliva CAEBV samples and other conditions. We observed EBV deletions in blood, some of which may disrupt viral replication, but not saliva in CAEBV. Deletions were lost overtime after successful treatment. These findings are compatible with CAEBV being associated with the evolution and persistence of EBV+ haematological clones that are lost on successful treatment.
- 1 May 2021
- Published by IOP Publishing in Plasma Sources Science and Technology
- Vol. 30 (5) , 055011
Studies of a modulated Hall thruster
A typical Hall thruster is powered from a DC power supply and operates with a constant discharge voltage. In operation, the discharge current is subject to strong low frequency oscillations (so-called breathing oscillations). Recent studies have shown that not only can these breathing oscillations be correlated with improved performance, but these oscillations can be induced and controlled by modulating the anode voltage. In this work, a systematic experimental study of the plasma flow in a modulated cylindrical Hall thruster was performed to characterize the effect of natural and modulated breathing oscillations on thruster performance. Measurements suggest that modulating the anode voltage in resonance with the natural breathing frequency does increase the thrust, but a corresponding phase alignment of discharge current and discharge voltage causes the efficiency gains to be insignificant. In addition, the outward shift of the acceleration region causes the plasma plume divergence to increase at the resonance condition and thereby, limit the thrust increase. Mechanisms underlying the relative phase between discharge current, ion current, and discharge voltage are investigated experimentally and corroborated with one-dimensional hybrid simulations of the thruster discharge.
- 1 May 2021
- Published by IOP Publishing in Plasma Sources Science and Technology
- Vol. 30 (5) , 055011
Studies of a modulated Hall thruster
A typical Hall thruster is powered from a DC power supply and operates with a constant discharge voltage. In operation, the discharge current is subject to strong low frequency oscillations (so-called breathing oscillations). Recent studies have shown that not only can these breathing oscillations be correlated with improved performance, but these oscillations can be induced and controlled by modulating the anode voltage. In this work, a systematic experimental study of the plasma flow in a modulated cylindrical Hall thruster was performed to characterize the effect of natural and modulated breathing oscillations on thruster performance. Measurements suggest that modulating the anode voltage in resonance with the natural breathing frequency does increase the thrust, but a corresponding phase alignment of discharge current and discharge voltage causes the efficiency gains to be insignificant. In addition, the outward shift of the acceleration region causes the plasma plume divergence to increase at the resonance condition and thereby, limit the thrust increase. Mechanisms underlying the relative phase between discharge current, ion current, and discharge voltage are investigated experimentally and corroborated with one-dimensional hybrid simulations of the thruster discharge.
- Open Access
EBV deletions as biomarkers of response to treatment of Chronic Active Epstein Barr Virus
Chronic active Epstein Barr Virus (CAEBV) is a rare and severe condition occurring in previously healthy individuals associated with persistent EBV viraemia, fever, lymphadenopathy and hepatosplenomegaly. Specific deletions in the EBV genome have been found in CAEBV and certain lymphomas. However, it is unclear how stable these deletions are, whether they are present in different sites and how they evolve in response to treatment. We sequenced fifteen longitudinal blood samples from three CAEBV patients, comparing the results with 13 saliva samples from CAEBV patients and sequences from benign (both primary infection and reactivation) and malignant EBV-related conditions. We observed large EBV deletions in blood, some of which are predicted to disrupt viral replication, but not saliva from patients with CAEBV. Deletions were stable over time but were lost following successful peripheral blood stem cell transplants (PBSCT) or in one case, treatment with rituximab. Our results are consistent with the likelihood that certain deletions occurring in virus from patients with CAEBV are associated with the evolution and persistence of haematological clones. We propose that the loss of EBV deletions following successful treatment should be investigated as a potential biomarker to aid management of CAEBV. Key points Unique EBV deletions are found in European CAEBV patients. Loss of deletions occurs following effective treatment and may prove useful in the management of disease.
Open AccessEBV deletions as biomarkers of response to treatment of Chronic Active Epstein Barr Virus
Chronic active Epstein Barr Virus (CAEBV) is a rare and severe condition occurring in previously healthy individuals associated with persistent EBV viraemia, fever, lymphadenopathy and hepatosplenomegaly. Specific deletions in the EBV genome have been found in CAEBV and certain lymphomas. However, it is unclear how stable these deletions are, whether they are present in different sites and how they evolve in response to treatment. We sequenced fifteen longitudinal blood samples from three CAEBV patients, comparing the results with 13 saliva samples from CAEBV patients and sequences from benign (both primary infection and reactivation) and malignant EBV-related conditions. We observed large EBV deletions in blood, some of which are predicted to disrupt viral replication, but not saliva from patients with CAEBV. Deletions were stable over time but were lost following successful peripheral blood stem cell transplants (PBSCT) or in one case, treatment with rituximab. Our results are consistent with the likelihood that certain deletions occurring in virus from patients with CAEBV are associated with the evolution and persistence of haematological clones. We propose that the loss of EBV deletions following successful treatment should be investigated as a potential biomarker to aid management of CAEBV. Key points Unique EBV deletions are found in European CAEBV patients. Loss of deletions occurs following effective treatment and may prove useful in the management of disease.