Savaş Kanbur

This study aims to investigate the impact of cardiorespiratory fitness on cardiometabolic risk factors and testosterone levels among firefighters. A cross-sectional descriptive study was conducted with seventy-four firefighters working in a metropolitan municipality. Anthropometric measurements, cardiometabolic risk parameters (high density lipoprotein, low density lipoprotein, triglycerides, total cholesterol), total testosterone (TT) levels were clinically evaluated for each participant. The proportion of firefighters with low TT was 20.3%, and a statistically significant negative relationship was found between TT and weight, BMI, body fat percentage, waist circumference, hip circumference, and HbA1c as cardiometabolic risk factors (p < 0.05). Additionally, statistically significant positive relationship was observed between metabolic equivalent scores and testosterone levels among the firefighters (p < 0.05). The key findings of this study reveal significant differences in various cardiometabolic risk factors between firefighters with high fitness levels and those with lower fitness levels.

Plant extracts (PE), fixed oils (FO) and essential oils (EO) are used in traditional medicine to treat various diseases. Therefore, in this study evaluated the anticandidal activity of 100 different commercially available PEs, FOs, and EOs against 19 Candida albicans vaginal isolates and C. albicans ATCC 10231. It was determined that 20 EOs and FOs had anticandidal activity. It was determined that Piper nigrum FO, pine turpentine EO, pine tar EO, and Eugenia caryophyllata EO showed the highest anticandidal activity. The minimum inhibitory concentrations (MIC) and minimum fungicidal concentrations (MFC) values of these FO and EOs were between 0.125 and 2 µL mL-1. The volatile components of these FOs and EOs were determined by GC-MS analysis. There were six components in E. caryophyllata EO, 38 in Pine turpentine EO, 39 in P. nigrum FO, and 119 in Pine tar EO. In conclusion, this FOs and EOs can be used to treat vulvovaginal candidiasis.

Introduction: Familial Mediterranean Fever (FMF) is a common autoinflammatory disease, especially in Mediterranean populations. FMF typically occurs with fever and serositis attacks and can negatively affect the individual's life. In our study, we aimed to investigate the effects of working conditions and the disease course on the work life of FMF patients. Methods: The adult patients with pathogenic or likely pathogenic mutations in the MEFV gene who applied to our medical genetic outpatient clinic of the Faculty of Medicine, Çanakkale Onsekiz Mart University between 01.01.2010 and 01.08.2020 were included in our study. We created a questionnaire of 34 questions, which included sociodemographic data, information about the FMF course of the patients, and the effects of work conditions and FMF on the work life of these patients. The questionnaire link, created over Google Drive, was sent to the patient's current mobile phone numbers via text message, and the answers received until 31.12.2020 were evaluated. Results: A total of 154 survey responses were obtained, and 113 were eligible for our study. Twenty-four of 104 (23.1%) participants who have worked in any job so far stated that they have changed or quit their jobs because of increased or worsening FMF attacks. Of 72 participants who have been working actively for the last year, 4 (5.6%) of them we are reported that they have a health problem in the workplace due to FMF disease. The statistically significant relationships were found between the FMF-induced changing or quitting job and the attack number in the last year regardless of attack severity, work-related adverse psychological effects, the mode of transportation to work, and the physical conditions in the working environment. Conclusion: We suggest that the regulation of work environments, considering the factors that trigger attacks in FMF patients, will contribute to the increase in quality of life and work performance in these patients.

Objective: Haematological to investigate the effects of heat stress on some haematological parameters among food industry employees working in the production department. Method: The ambispective, single-centre, case-control study was conducted from December 1, 2016, to June 6, 2018, at Istanbul Gedik University and the Okan University, Istanbul, which is part of the Marmara region of Turkey. The study comprised subjects of either gender aged 22-57 years. Those working in the food industry were the cases in group A, while healthy controls formed group B. Within group A, subjects who were office workers formed subgroup A1, while those in the production department working in the heat treatment areas exposed to high temperatures formed subgroup A2. Heat stress in the environment was evaluated using the Wet Bulb Globe Temperature index. Peripheral blood haemoglobin and platelet levels, neutrophil-lymphocyte ratio and platelet-lymphocyte ratio were compared between the cases and the controls. Data was analysed using SPSS 22. Results: Of the 257 subjects, 139(54.1%) were women and 118 45.9%) were men. The overall mean age was 35.07±7.32. There were 143(55.6%) subjects in group A and 114(44.4%) in group B. Within group A, 19(13.3%) subjects were in subgroup A1 and 124(86.7%) in subgroup A2. The mean working duration for group A was 9.95±4.37 years (range: 5-24 years with). Haemoglobin and platelet levels were significantly lower and the neutrophil-lymphocyte ratio was significantly higher in subgroup A2 compared to those in subgroup A1 and group B (p-lymphocyte ratio (p=0.486). Conclusion: Differences in haematological parameters were significantly different in individuals who worked in the production department and were exposed to heat stress compared to those who did not. Key Words: Haematological parameters, Heat stress, Food industry, Production department, Occupational health.

After air pollution, the most important environmental factor threatening human health is noise. Physiologic damage or psychological damage can occur because of noise. Increased oxidative stress, vascular changes and mechanical trauma may be responsible for the physiologic damage mechanism of noise. This study aimed to reveal the effect of noise on follicles in ovaries. In the study, a total of 30 female Wistar albino rats (12 weeks old) were randomly divided into three groups (n = 10): the control group, no treatment; the sham group, exposed to stress conditions (but not to any high waves) in a special room at the same time as the high sound wave group; and the high sound wave (HSW) group, exposed to HSW in a special room for 28 days. At the end of the 28th day, the rats were sacrificed and ovarian tissues were harvested. Stereologic and biochemical analyses were performed. All stereologic volumetric parameters and Gonadal Somatic Index (GSI) values, lipid peroxidation (LPO) and glutathione (GSH) levels in all groups were evaluated statistically, and significant differences were found between the control and HSW, sham and HSW groups, respectively. However, no statistical difference was found between the control and sham groups. A decrease in catalase (CAT) and superoxide dismutase (SOD) activities were found in the HSW group compared with the control and sham groups, suggesting that noise can cause oxidative stress and damage to the ovaries.

Madencilik ve y apı sektöründe karot numunesi alma işlemlerinde operatör olarak çalışanların maruz kaldığı gürültü, toz ve sıcaklık gibi farklı türden risk etmenlerine bağlı sağlık sorunlarının ortaya çıktığı bilinmektedir. Bu araştırma, Marmara Bölgesi’nde madencilik ve yapı sektöründe karot operatörü olarak çalışan evli erkeklerin üreme sağlığı durumlarının tespiti amacıyla yapılmıştır.

Vulvovaginal complaints are one of the top reasons for applying to medical institutions in women. Vulvovaginal infections also take an important place in chief complaints in sexually transmitted diseases in women. Sexually transmitted diseases can cause permanent reproductive health problems in women. This situation shows the importance of the fact that sexually transmitted diseases must be diagnosed in patient population who apply to medical institutions with vulvovaginal infection symptoms. Today bacterial, parasitic and fungal vulvovaginal infection causes like Candida Albicans, Gardnerella Vaginalis, Trichomonas Vaginalis, N. Gonorrhoeae, Syphilis make up 80% of the total vulvovaginal diseases. In this cross-sectional study, having information on the frequency of sexually transmitted diseases in Turkey indirectly and comparison of treatment options are aimed.