Hasan Bostancı

Globally, sociocultural factors often pose significant barriers for patients in seeking medical attention and accessing appropriate treatment. This study aims to evaluate the knowledge, attitudes, and practices regarding anal fistula and other proctological conditions in Turkiye. The findings will help identify gaps in health education and support the development of targeted public health interventions. This research is a cross-sectional survey study conducted among individuals who applied to a tertiary care center. Participants were consecutively recruited and consisted of individuals aged 18 and over who visited the general surgery outpatient clinic for any reason. Data were collected through an online questionnaire based on Google Forms. The survey included questions on demographic information, disease awareness, attitudes toward treatment, and healthcare-seeking behavior. A knowledge, attitudes, and practices (KAP) analysis was performed to assess participants’ understanding of the disease, their treatment preferences, and health-related practices. A total of 702 participants were included in the analysis, of whom 377 (53.7%) were female and 325 (46.3%) were male. A history of at least one proctological disease was reported by 332 individuals (47.2%), and 115 participants (16.3%) had undergone surgery for a proctological condition at least once. Traditional treatment methods had been tried by 73 respondents (10.3%). A total of 330 participants (46.9%) stated they were aware of the causes of anal fistula; however, only 143 (43.3%) of them gave correct answers. The total KAP score was significantly lower among participants with primary education compared with those with higher education ( P = .02). Participants over the age of 45 had significantly higher total KAP scores compared with both younger age groups (≤30 and 31–45 years; P < .001). In addition, participants with a history of proctological disease or a diagnosis of anal fistula had significantly higher KAP scores ( P < .05). Raising awareness of proctological diseases in Turkiye remains a significant challenge. On the basis of the findings of the KAP analysis, it is essential to identify knowledge gaps and misconceptions and to develop educational and public health strategies aimed at improving community health outcomes.

Background: Hospital indoor environments contain a wide variety of microorganisms. Bacteria, viruses, and fungi in these environments can cause serious healthcare-associated infections in patients. The aim of this study is to show the mycoflora of the hospital by evaluating the distribution of fungal species in hospital indoor air, water, and surfaces. Methods: Air, water, and surface were sampled for fungi at Gazi University Hospital, using active air method, water collection, and swabbing, during a five-month period in 2022-2023. A total of 22 hospital wards were surveyed; overall, 110 air samples, 66 water samples, and 45 surface samples were collected. Results: A total of 1331 fungal colonies were isolated from indoor air, predominantly Penicillium (57.7%) and Cladosporium (31.6%). From outdoor air (n = 471), Cladosporium (66.9%) and Penicillium (22.5%) were most common. Median colony counts per 500 L of air were 11.5 indoors and 30.0 outdoors (range: 4–21.1 and 9–55.6, respectively. Fungal diversity, as evaluated by the Shannon index, peaked in March for both environments. Fungal growth was observed in 17 of 66 water samples (26.0%), with a total of 225 colonies recovered. Penicillium spp. accounted for the majority (85.7%), followed by Exophiala (8.0%) and Aspergillus (5.0%).Among 45 surface samples, only 3 (6.0%) yielded fungal isolates, indicating low environmental fungal burden on high-touch surfaces. Conclusion: The findings demonstrate that hospital environments, especially air and water sources, are significantly colonized by diverse fungal genera—predominantly Penicillium and Cladosporium—highlighting the importance of routine environmental mycological monitoring to mitigate potential nosocomial risks.

Abdominal açık cerrahiler sonrası spora dönüş, fonksiyonel toparlanma ve yaşam kalitesinin önemli bir göstergesidir. Erken mobilizasyon komplikasyon riskini azaltırken, prehabilitasyon programları iyileşmeyi hızlandırmaktadır. Spor aktivitelerine dönüş basamaklı ve bireyselleştirilmiş olmalı, temas sporları genellikle 3–6 ay sonra önerilmektedir. İnsizyonel herni ve enfeksiyon gibi komplikasyonlar süreci uzatmaktadır. Multidisipliner yaklaşımın, objektif ölçüm yöntemleriyle desteklenmiş kişiselleştirilmiş planlarla daha başarılı sonuçlar sağladığı gösterilmiştir.

Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm of mesenchymal origin arising from B‐cell follicles, typically presenting as a painless, slow‐growing mass. According to the available literature, this is only the second reported case of FDCS during pregnancy and the first associated with fetal growth restriction and preeclampsia. A 30‐year‐old pregnant woman at 28 weeks of gestation was diagnosed with preeclampsia and fetal growth restriction, during which an incidental abdominal mass was identified on ultrasound. Excisional surgery was performed 27 days after an emergency cesarean delivery, and histopathological analysis confirmed FDCS arising in association with hyaline‐vascular type Castleman disease. This case highlights the importance of multidisciplinary evaluation and awareness of rare abdominal neoplasms during pregnancy.

Background and Objectives: Sepsis and its related complications are associated with high morbidity and mortality, often leading to liver damage. Ozone, a molecule with anti-inflammatory and antioxidant properties, may offer protective effects. This study aimed to evaluate the therapeutic and protective impact of ozone on liver injury in a rat model of sepsis induced by cecal ligation and perforation (CLP). Material and Methods: A total of 36 rats were randomly divided into five groups: control (Group C), ozone (Group O), cecal ligation and perforation (Group CLP), ozone + cecal ligation and perforation (Group O+CLP), and cecal ligation and perforation + ozone (Group CLP+O). In the ozone groups, 4 mL of ozone (20 µ/mL) was injected intraperitoneally. Biochemical and histopathological parameters were evaluated in liver tissue samples obtained at the end of 24 h. Results: Polymorphonuclear leukocyte and monocyte infiltration and the total injury score were significantly reduced in the ozone-treated groups compared to the CLP group (p < 0.001). Tumor necrosis factor and interleukin 10 levels in the rat liver tissue were significantly reduced in the O+CLP and CLP+O groups compared to the CLP group, with the O+CLP group showing a more substantial decrease than the CLP+O group (p < 0.001). Thiobarbituric acid reactive substances and glutathione s-transferase levels were significantly lower in the ozone-treated groups compared to the CLP group (p < 0.001). Catalase activity was significantly elevated in the O+CLP group compared to the CLP group (p < 0.001). Serum aspartate transaminase, alanine transaminase, gamma-glutamyl transferase, and total bilirubin were significantly increased in the CLP group and decreased in the ozone-treated groups (p < 0.001, p < 0.001, p = 0.01, p < 0.001 respectively). Conclusions: Administering ozone to rats one hour before the CLP significantly mitigated liver damage, showing a more pronounced effect compared to administering ozone one hour after CLP. The results indicate that ozone could serve a protective function in managing sepsis-induced liver damage.

Kist hidatik, özellikle koyun otlatma bölgelerinde yaygın olan, Echinococcus türlerinin neden olduğu bir zoonotik enfeksiyondur. Hastalık, insanlarda çoğunlukla karaciğer ve akciğerlerde kist oluşumuna yol açar. Tanı, serolojik testler ve görüntüleme yöntemleri ile konur. Tedavi cerrahi, medikal ve alternatif yöntemlerle gerçekleştirilir. Cerrahi müdahale genellikle gerekli olmakla birlikte, bazı durumlarda medikal tedavi veya PAIR yöntemi tercih edilebilir. Komplikasyonlar arasında rüptür, anaflaksi ve sekonder enfeksiyonlar bulunur. Hydatid cyst is a zoonotic infection caused by Echinococcus species, prevalent in regions where sheep grazing is common. The disease typically leads to cyst formation in the liver and lungs in humans. Diagnosis is achieved through serological tests and imaging studies. Treatment includes surgical, medical, and alternative methods. Surgery is often necessary, but in some cases, medical therapy or the PAIR technique may be employed. Complications include rupture, anaphylaxis, and secondary infections.