Nicholas Sellke
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Previous Organizations / Institutes
The organizations / institutes from the scholar's other articles in the past ten years
Research Subjects
Nicholas Sellke has a total of 68 co-authors. Here are the top co-authors by number of shared publications:
Nannan Thirumavalavan
Case Western Reserve University School of Medicine, Cleveland, OH, USA
8 shared publicationsAram Loeb
Case Western Reserve University School of Medicine, Cleveland, OH, USA
6 shared publicationsStephen Rhodes
Urology Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, USA
6 shared publications- Kimberly Tay
Case Western Reserve University School of Medicine, Cleveland, OH, USA
5 shared publications Ramy Abou Ghayda
Case Western Reserve University School of Medicine, Cleveland, OH, USA
5 shared publicationsHelen H. Sun
Case Western Reserve University School of Medicine, Cleveland, OH, USA
3 shared publications
Latest Publications
- Open Access
- 19 October 2026
- Published by Springer Nature in International Journal Of Impotence Research
- p. 1-2
Comment on: GLP-1 receptor agonists and male sexual health: translating cardiometabolic benefits into erectile outcomes
- 19 October 2026
- Published by Springer Nature in International Journal Of Impotence Research
- p. 1-2
Open AccessComment on: GLP-1 receptor agonists and male sexual health: translating cardiometabolic benefits into erectile outcomes
- Open Access
- 1 January 2026
- Published by XMLink in The World Journal of Men's Health
- Vol. 44
Accelerating Decline in Serum Testosterone across Birth Cohorts: A Systematic Review and Meta-Regression Analysis
Negri F, et al. World J Mens Health. 2026 ;44:e82. https://doi.org/10.5534/wjmh.260136
- 1 January 2026
- Published by XMLink in The World Journal of Men's Health
- Vol. 44
Open AccessAccelerating Decline in Serum Testosterone across Birth Cohorts: A Systematic Review and Meta-Regression Analysis
Negri F, et al. World J Mens Health. 2026 ;44:e82. https://doi.org/10.5534/wjmh.260136
- 13 August 2025
- Published by Springer Nature in International Journal Of Impotence Research
Testosterone testing in the United States: limited price transparency and significant variability
In response to the 2021 Hospital Price Transparency Regulation by The Centers for Medicare & Medicaid Services (CMS), we evaluated hospital-reported price transparency and variability for testosterone (T) testing across the United States (US). Using the Turquoise database, hospitals disclosing free or total T test prices were identified. Hospital characteristics were compared between price reporters and non-reporters. Multivariable regression identified reporting predictors and assessed price variability by test and payer type. Of 6700 hospitals, 51.7% reported at least one T test price. Reporting was more common among larger hospitals (median 100 vs. 75 beds, p < 0.001), non-profits (62.7 vs. 44.3%, p < 0.001), and those with higher compliance scores (4.5 vs. 3, p < 0.001). Regional variation was significant (p < 0.001), but no urban-rural differences were observed (p = 0.71). Median prices were $84.90 (Interquartile range $44.0, $138.0) for total T and $92.27 ($49.17, $144.35) for free T, varying by payer: $79.43 ($40.82, $131.32) for commercial insurance and $98.00 ($54.65, $148.84) for self-pay. On multivariable analysis, hospitals in competitive markets and with more beds tended to have lower prices, while hospital ownership did not significantly affect pricing. Despite the legislation, nearly half of hospitals fail to report prices, driving significant price variation and limiting informed consumer choices.
- 13 August 2025
- Published by Springer Nature in International Journal Of Impotence Research
Testosterone testing in the United States: limited price transparency and significant variability
In response to the 2021 Hospital Price Transparency Regulation by The Centers for Medicare & Medicaid Services (CMS), we evaluated hospital-reported price transparency and variability for testosterone (T) testing across the United States (US). Using the Turquoise database, hospitals disclosing free or total T test prices were identified. Hospital characteristics were compared between price reporters and non-reporters. Multivariable regression identified reporting predictors and assessed price variability by test and payer type. Of 6700 hospitals, 51.7% reported at least one T test price. Reporting was more common among larger hospitals (median 100 vs. 75 beds, p < 0.001), non-profits (62.7 vs. 44.3%, p < 0.001), and those with higher compliance scores (4.5 vs. 3, p < 0.001). Regional variation was significant (p < 0.001), but no urban-rural differences were observed (p = 0.71). Median prices were $84.90 (Interquartile range $44.0, $138.0) for total T and $92.27 ($49.17, $144.35) for free T, varying by payer: $79.43 ($40.82, $131.32) for commercial insurance and $98.00 ($54.65, $148.84) for self-pay. On multivariable analysis, hospitals in competitive markets and with more beds tended to have lower prices, while hospital ownership did not significantly affect pricing. Despite the legislation, nearly half of hospitals fail to report prices, driving significant price variation and limiting informed consumer choices.
- Open Access
- 1 January 2025
- Published by XMLink in The World Journal of Men's Health
- Vol. 44
The Effect of Intratesticular Platelet-Rich Plasma Injection on Sperm Retrieval Rates in Non-Obstructive Azoospermia Male after Failed Testicular Sperm Extraction: An Inception Cohort
Basran SS, et al. World J Mens Health. 2026 Jan;44:e4. https://doi.org/10.5534/wjmh.250281
- 1 January 2025
- Published by XMLink in The World Journal of Men's Health
- Vol. 44
Open AccessThe Effect of Intratesticular Platelet-Rich Plasma Injection on Sperm Retrieval Rates in Non-Obstructive Azoospermia Male after Failed Testicular Sperm Extraction: An Inception Cohort
Basran SS, et al. World J Mens Health. 2026 Jan;44:e4. https://doi.org/10.5534/wjmh.250281
- Open Access
- 1 January 2025
- Published by Tech Science Press in Canadian Journal of Urology
- Vol. 32 (2) , 89-94
The cost and guideline adherence of direct-to-consumer telemedicine companies offering gender-affirming hormone therapy
Introduction: Direct-to-consumer (DTC) telemedicine has emerged as an option for transgender patients seeking gender affirming hormone therapy (GAHT). We aimed to characterize the healthcare services provided by DTC telemedi... | Find, read and cite all the research you need on Tech Science Press
- 1 January 2025
- Published by Tech Science Press in Canadian Journal of Urology
- Vol. 32 (2) , 89-94
Open AccessThe cost and guideline adherence of direct-to-consumer telemedicine companies offering gender-affirming hormone therapy
Introduction: Direct-to-consumer (DTC) telemedicine has emerged as an option for transgender patients seeking gender affirming hormone therapy (GAHT). We aimed to characterize the healthcare services provided by DTC telemedi... | Find, read and cite all the research you need on Tech Science Press
- Open Access
- 10 April 2024
- Published by Springer Nature in International Journal Of Impotence Research
- Vol. 37 (4) , 288-292
Malpractice litigation related to management of varicocele: a legal database review
- 10 April 2024
- Published by Springer Nature in International Journal Of Impotence Research
- Vol. 37 (4) , 288-292
Open AccessMalpractice litigation related to management of varicocele: a legal database review
- Open Access
- 22 February 2024
- Published by Springer Nature in International Journal Of Impotence Research
Uncovering the interhospital price variations for vasectomies in the United States
Due to the historic lack of transparency in healthcare pricing in the United States, the degree of price variation for vasectomy is largely unknown. Our study aims to assess characteristics of hospitals reporting prices for vasectomy as well as price variation associated with hospital factors and insurance status. A cross-sectional analysis was performed in October, 2022 using the Turquoise Database which compiles publicly available hospital pricing data. The database was queried for vasectomy prices to identify the cash (paid by patients not using insurance), commercial (negotiated by private insurers) and Medicare and Medicaid prices for vasectomies. Hospital characteristics of those that reported a price for vasectomy and those that did not were compared and pricing differences based on hospital ownership and reimbursement source were determined using multivariable linear regression analysis. Overall, only 24.7% (1657/6700) of hospitals reported a price for vasectomy. Those that reported a price had more beds (median 117 vs 80, p < 0.001), more physicians (median 1745 vs 1275, p < 0.001). They were also more likely to be nonprofit hospitals (77% vs 14%, p < 0.001) and to be in well-resourced areas (ADI 91.7 vs 94.4, p < 0.001). Both commercial prices and cash prices for vasectomy were lower at nonprofit hospitals than at for-profit hospitals (commercial: $1959.47 vs $2861.56, p < 0.001; cash: $1429.74 vs $3185.37, p < 0.001). Our study highlights the current state of pricing transparency for vasectomy in the United States. Patients may be counseled to consider seeking vasectomy at a nonprofit hospital to reduce their costs, especially when paying with cash. These findings also suggest a need for new policies to target areas with decreased price transparency to reduce price disparities.
- 22 February 2024
- Published by Springer Nature in International Journal Of Impotence Research
Open AccessUncovering the interhospital price variations for vasectomies in the United States
Due to the historic lack of transparency in healthcare pricing in the United States, the degree of price variation for vasectomy is largely unknown. Our study aims to assess characteristics of hospitals reporting prices for vasectomy as well as price variation associated with hospital factors and insurance status. A cross-sectional analysis was performed in October, 2022 using the Turquoise Database which compiles publicly available hospital pricing data. The database was queried for vasectomy prices to identify the cash (paid by patients not using insurance), commercial (negotiated by private insurers) and Medicare and Medicaid prices for vasectomies. Hospital characteristics of those that reported a price for vasectomy and those that did not were compared and pricing differences based on hospital ownership and reimbursement source were determined using multivariable linear regression analysis. Overall, only 24.7% (1657/6700) of hospitals reported a price for vasectomy. Those that reported a price had more beds (median 117 vs 80, p < 0.001), more physicians (median 1745 vs 1275, p < 0.001). They were also more likely to be nonprofit hospitals (77% vs 14%, p < 0.001) and to be in well-resourced areas (ADI 91.7 vs 94.4, p < 0.001). Both commercial prices and cash prices for vasectomy were lower at nonprofit hospitals than at for-profit hospitals (commercial: $1959.47 vs $2861.56, p < 0.001; cash: $1429.74 vs $3185.37, p < 0.001). Our study highlights the current state of pricing transparency for vasectomy in the United States. Patients may be counseled to consider seeking vasectomy at a nonprofit hospital to reduce their costs, especially when paying with cash. These findings also suggest a need for new policies to target areas with decreased price transparency to reduce price disparities.
- Open Access
- 28 September 2023
- Published by SAGE Publications in American Journal of Men's Health
- Vol. 17 (5)
The Variability of Semen Parameters With Sexual Abstinence Using Mail-in Sperm Testing Is Similar to That Seen With Traditional In-Office Semen Analysis
The impact of ejaculatory abstinence on semen parameters using in-office semen analyses has been well-established; however, their variability has not been evaluated in men using mail-in semen analysis kits. Our study aims to describe how the sperm parameters using mail-in semen analysis tests change with abstinence and validate their equivalence to those seen with in-office semen analysis tests. We retrospectively reviewed the semen analysis results of men using mail-in semen analysis tests provided by Give Legacy, Inc (Legacy) facilities from 2019 to 2021. We collected their demographic information, abstinence duration, and semen parameters (conventional and kinematic) from their records. Semen samples were categorized as normozoospermic and oligozoospermic based on concentration. The shape of the relationship between abstinence duration and semen parameters was assessed via generalized additive models. We have collected 3,469 unique samples provided by 2,609 (75%) normozoospermic men and 860 (25%) oligozoospermic from all over the United States. In normozoospermic men, longer periods of sexual abstinence were linked to higher levels of sperm concentration, total sperm count, and total motile sperm. However, there was a decline in both total and progressive motility. Conversely, in oligozoospermic men, extended periods of abstinence led to a rapid decline in total motile sperm, as well as total and progressive motility. There was no significant correlation observed between sexual abstinence and variations in sperm morphology. Our study shows that variability of sperm parameters with abstinence, as measured through mail-in semen analysis tests, is comparable to the patterns observed with conventional in-office sperm testing.
- 28 September 2023
- Published by SAGE Publications in American Journal of Men's Health
- Vol. 17 (5)
Open AccessThe Variability of Semen Parameters With Sexual Abstinence Using Mail-in Sperm Testing Is Similar to That Seen With Traditional In-Office Semen Analysis
The impact of ejaculatory abstinence on semen parameters using in-office semen analyses has been well-established; however, their variability has not been evaluated in men using mail-in semen analysis kits. Our study aims to describe how the sperm parameters using mail-in semen analysis tests change with abstinence and validate their equivalence to those seen with in-office semen analysis tests. We retrospectively reviewed the semen analysis results of men using mail-in semen analysis tests provided by Give Legacy, Inc (Legacy) facilities from 2019 to 2021. We collected their demographic information, abstinence duration, and semen parameters (conventional and kinematic) from their records. Semen samples were categorized as normozoospermic and oligozoospermic based on concentration. The shape of the relationship between abstinence duration and semen parameters was assessed via generalized additive models. We have collected 3,469 unique samples provided by 2,609 (75%) normozoospermic men and 860 (25%) oligozoospermic from all over the United States. In normozoospermic men, longer periods of sexual abstinence were linked to higher levels of sperm concentration, total sperm count, and total motile sperm. However, there was a decline in both total and progressive motility. Conversely, in oligozoospermic men, extended periods of abstinence led to a rapid decline in total motile sperm, as well as total and progressive motility. There was no significant correlation observed between sexual abstinence and variations in sperm morphology. Our study shows that variability of sperm parameters with abstinence, as measured through mail-in semen analysis tests, is comparable to the patterns observed with conventional in-office sperm testing.