Fabiana Gatto

Nutraceuticals are an ever-expanding market worldwide, facing the unstoppable transition towards a green economy. Developing economically feasible and sustainable alternatives to current raw materials for the extraction of nutraceuticals is, therefore, essential to reach these goals and, at the same time, achieve social and economic competitiveness. This paper intends to propose an economical and environmentally sustainable feedstock for chlorogenic acid (CGA) and inulin, whose current extraction from green coffee and chicory, respectively, is unsustainable. Our approach is based on the multi-criteria decision-making approach (MCDA), supported by the analytical hierarchy process (AHP), ranking the performance of competitor biomasses according to economic, social, and technological criteria. The results of this study highlight cardoon (Cynara cardunculus) as a promising raw material for the extraction of CGA and inulin in virtue of the high concentration, low-input growth regime, and the possibility of being grown on marginal lands. Nevertheless, cardoon biomass availability is currently scarce, extraction methods are underdeveloped, and consequently, the obtained product’s price is higher than the benchmark competitors. Policies and investments favoring sustainable cultivations could stimulate cardoon employment, linking economic advantages and land requalification while limiting phenomena such as desertification and food competition in the Mediterranean basin.

Regional policies play a pivotal role in green transition and pursuing the European Green Deal decarbonization targets. Despite the general recognition of the strategic value of the bioeconomy in realizing this challenge, regional roadmaps for its growth are not yet a widespread tool in local innovation policy. Conversely, driving green investments by measuring the innovation potential of the bioeconomy could shape a low-carbon economy by leveraging the full potential of local resources. In order to validate a replicable decision-making model driving 2021–2027 ERDF funds towards this mission, this paper measures the economic, social and technological impact of the Lombard bioeconomy through five applications and eight criteria. The methodology allows quantification of the local bioeconomy value and, through a Multi-Criteria Decision Analysis (MCDA), identifies the bio-based applications with the highest innovation potential. By measuring the current and prospective impact of the bioeconomy, Bio-chemicals, Agri-foods, and Biopolymers emerges as the applications with the highest innovation potential rate for Lombardy. Five recommendations to drive green investments and shape the regional roadmap for the bioeconomy are finally defined, providing a tool for industrial applications with a greater impact on local competitiveness.

Reducing the environmental pressure along the products life cycle, increasing efficiency in the consumption of resources and use of renewable raw materials, and shifting the economic system toward a circular and a climate-neutral model represent the heart of the current macro-trends of the European Union (EU) policy agendas. The circular economy and bioeconomy concepts introduced in the EU’s Circular Economy Action Plan and the Bioeconomy Strategy support innovation in rethinking economic systems focusing on market uptaking of greener solutions based on less-intensive resource consumption. In recent decades, industrial research has devoted enormous investments to demonstrate sustainable circular bio-based business models capable of overcoming the “Valley of Death” through alternative strategic orientations of “technological-push” and “market-pull”. The study highlights industrial research’s evolution on bio-based circular business model validation, trends, and topics with particular attention to the empowering capacity of start-ups and small and medium-sized enterprises (SMEs) to close the loops in renewable biological use and reduce dependence on fossil fuels. The research methodology involves a bibliographic search based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) approach and the European Innovation Council (EIC) Accelerator Data Hub investigation to understand SMEs’ key success factors and start-ups of the circular bioeconomy sector. Eco and bio-based materials, nutraceuticals, and microalgae represent the most sustainable industry applications, leading to circular bioeconomy business models’ future perspective.