Laura Macca

Citation: Di Bartolomeo L, Vaccaro F, Borgia F, Macca L, Portuese S, Vaccaro M. Super-High Magnification Entodermoscopy: The New Era of Dermoscopy in the Field of Skin Parasitoses. Dermatol Pract Concept. 2024;14(1):e2024021. DOI: https://doi.org/10.5826/dpc.1401a21 Accepted: June 8, 2023; Published: January 2024 Copyright: ©2024 Di Bartolomeo et al. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (BY-NC-4.0), https://creativecommons.org/licenses/by-nc/4.0/, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original authors and source are credited. Funding: None. Competing interests: None. Authorship: All authors have contributed significantly to this publication. Corresponding author: Luca Di Bartolomeo, Viale della Repubblica, 23 – 84047 Capaccio-Paestum, Salerno, Italy; e-mail: lucadibartolomeo@live.it Keywords : entodermoscopy, super-high magnification dermoscopy, scabies, pediculus, pthirus This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

BACKGROUND: Perforating dermatoses are heterogeneous skin disorders characterized by transepidermal elimination of dermal tissue components. They can be characterized by the primary or secondary pathogenesis. Primary perforating dermatoses can be divided into four types, according to the eliminated dermal materials: Kyrle disease, perforating reactive collagenosis, elastosis perforans serpiginosa, and perforating folliculitis. The secondary form is also known as acquired perforating dermatosis and designates adult patients with coexisting systemic diseases, regardless of the dermal materials eliminated. The aim of this review is to investigate the potential relationship between Kyrle disease and associated conditions, reporting a rare case of this disease in a patient with chronic kidney disease. CASE PRESENTATION: We report the case of a 55-year-old male patient who presented generalized pruritus and skin lesions on the upper limbs and trunk for about 6 months. Pathological history revealed systemic arterial hypertension and chronic kidney disease (CKD), for which the patient had been on hemodialysis since more than 3 years. CONCLUSION: We reviewed the literature, reporting a rare case of KD in a patient with chronic renal failure on hemodialysis. KD is an acquired dermatologic condition that lacks a standardized treatment approach and can be notoriously difficult to cure. This article provides an overview of the most frequent comorbidities and treatment methodologies previously reported in the literature. If KD is suspected, underlying systemic disorders need to be investigated.

Hidradenitis suppurativa (HS) is a chronic, debilitating skin disease of the apocrine glands. Bibliographic search revealed few studies concerning the association between HS and human immunodeficiency virus (HIV). To assess this link, we performed a systematic review of the current knowledge through a careful analysis of the relevant and authoritative medical literature in the field. Results showed that people with HIV are particularly susceptible to developing HS with the characteristic involvement of atypical sites, such as face or thighs, due to HIV-related immunosuppression. Based on the pathogenesis of both conditions and according to our review, we suggest that HIV screening should be routinely performed in suspected cases while monitoring and integrated approach in management are mandatory in the management of HIV-positive patients with HS.

Citation: Macca L, Di Bartolomeo L, Guarneri C. Cobblestone-like skin. Dermatol Pract Concept. 2022;12(4):e2022200. DOI: https://doi.org/10.5826/dpc.1204a200 Accepted: March 2, 2022; Published: October 2022 Copyright: ©2022 Macca al. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (BY-NC-4.0), https://creativecommons.org/licenses/by-nc/4.0/, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original authors and source are credited. Funding: None. Competing interests: None. Authorship: All authors have contributed significantly to this publication. Corresponding author: Claudio Guarneri, MD, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Section of Dermatology, University of Messina, Messina, Italy C/O A.O.U.P. “Gaetano Martino”, via Consolare Valeria, 1 – 98125 Messina (Italy); Phone number: +390902212894. Fax number: +390902927691. E-mail: cguarneri@unime.it This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Several cutaneous manifestations in patients undergoing COVID-19 vaccination have been described in the literature. Herein, we presented a case of new-onset vitiligo that occurred after the second dose of the Comirnaty vaccine. An updated literature search revealed the occurrence of a total of 16 cases, including new-onset or worsening of preexisting vitiligo. Given the autoimmune pathogenesis of the disease, we reviewed and discussed the potential role of the vaccine prophylaxis as a trigger for the development of such hypopigmented skin lesions.

Psoriasis is a chronic immune-mediated skin and joint disease, with a plethora of comorbidities, characterized by a certain genetic predisposition, and a complex pathogenesis based on the IL-23/IL-17 pathway. There is no doubt that the patients affected by psoriasis are more susceptible to infections as well as that the risk of infection is higher in psoriatic subjects than in the general population. The advent of biotechnological agents on the therapeutic arsenal actually available for the treatment of moderate-to-severe patients, given the fact that the severity of the disease is a predictor of the level of infectious risk, has raised the question of whether these ‘new’ drugs could be considered a safer option and how they can be used in selected cases. Old and newer strategies in cases of chronic infectious conditions are reviewed under the light of clinical trials and other studies present in literature.

Morbihan Syndrome is an uncommon condition characterized by the slow appearance of erythema and solid edema on the upper portion of the face. The disease is considered an end-stage complication of rosacea's recurrent episodes of vascular dilation and inflammation or a complication of acne vulgaris. The disease is often insidious to diagnose and challenging to treat. We report a paradigmatic case of unilateral Morbihan Syndrome induced by use of full-face CPAP masks for OSAS in a patient with rosacea. OSAS could play a role in the development of rosacea symptoms. Our aim is to remark the importance of a careful, prolonged follow-up in order to optimize patient's management and to improve the adherence to therapy.