Safikur Rahman
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Safikur Rahman has a total of 6 co-authors. Here are the top co-authors by number of shared publications:
- Arif Tasleem Jan
Department of Botany, School of Biosciences and Biotechnology, Baba Ghulam Shah University, Rajouri 185234, India
1 shared publication - Ehab H. Mattar
Department of Biological Sciences, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia
1 shared publication - Elrashdy Moustafa Redwan
Department of Biological Sciences, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia
1 shared publication - Eun Ju Lee
Department of Medical Biotechnology and Research Institute of Cell Culture, Yeungnam University, Gyeongsan 38541, Korea
1 shared publication - Inho Choi
Department of Medical Biotechnology, Yeungnam University, Gyeongsan 38541, Republic of Korea
1 shared publication - Raied Badierah
Biological Science Department, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia
1 shared publication
Latest Publications
- Open Access
Expedition into Exosome Biology: A Perspective of Progress from Discovery to Therapeutic Development
Exosomes are membrane-enclosed distinct cellular entities of endocytic origin that shuttle proteins and RNA molecules intercellularly for communication purposes. Their surface is embossed by a huge variety of proteins, some of which are used as diagnostic markers. Exosomes are being explored for potential drug delivery, although their therapeutic utilities are impeded by gaps in knowledge regarding their formation and function under physiological condition and by lack of methods capable of shedding light on intraluminal vesicle release at the target site. Nonetheless, exosomes offer a promising means of developing systems that enable the specific delivery of therapeutics in diseases like cancer. This review summarizes information on donor cell types, cargoes, cargo loading, routes of administration, and the engineering of exosomal surfaces for specific peptides that increase target specificity and as such, therapeutic delivery.
Open AccessExpedition into Exosome Biology: A Perspective of Progress from Discovery to Therapeutic Development
Exosomes are membrane-enclosed distinct cellular entities of endocytic origin that shuttle proteins and RNA molecules intercellularly for communication purposes. Their surface is embossed by a huge variety of proteins, some of which are used as diagnostic markers. Exosomes are being explored for potential drug delivery, although their therapeutic utilities are impeded by gaps in knowledge regarding their formation and function under physiological condition and by lack of methods capable of shedding light on intraluminal vesicle release at the target site. Nonetheless, exosomes offer a promising means of developing systems that enable the specific delivery of therapeutics in diseases like cancer. This review summarizes information on donor cell types, cargoes, cargo loading, routes of administration, and the engineering of exosomal surfaces for specific peptides that increase target specificity and as such, therapeutic delivery.