Cigdem Elmas
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Cigdem Elmas has a total of 8 co-authors. Here are the top co-authors by number of shared publications:
- Ayşe Seçil Kayalı Dinç
Ankara Bilkent Şehir Hastanesi
1 shared publication - Eray Uzunoğlu
Department of Otorhinolaryngology, Faculty of Medicine, Bakırçay University, İzmir, Türkiye
1 shared publication - Esra Küpeli Akkol
Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Etiler, Ankara 06330, Türkiye
1 shared publication - Melih Cayonu
Department of Otorhinolaryngology, University of Health Science, Ankara Bilkent City Hospital, Ankara, Turkey
1 shared publication - Mert Ilhan
Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara, Turkey
1 shared publication - Metin Yılmaz
Department of Otorhinolaryngology, Gazi University Faculty of Medicine, Ankara, Turkey
1 shared publication
Latest Publications
- 6 May 2021
- Published by Springer Nature in European Archives of Oto-Rhino-Laryngology
- Vol. 279 (2) , 987-994
Effects of chitosan and platelet-rich plasma on facial nerve regeneration in an animal model
Purpose There is still no widely-accepted local agent proven to be effective in nerve regeneration. We aimed to investigate the effects of chitosan gel and platelet-rich plasma Materials and methods Electrophysiological measurements were performed before and immediately after injury. The injured nerves were covered with spongostan impregnated with the following agents: Group 1 (Control Group): Saline at a dose of 50 µl; Group 2: Chitosan (CHT) at a dose of 50 µl; Group 3: PRP at a dose of 50 ml; and Group 4: a solution of CHT with PRP (1:1). The final measurements were performed after 3 weeks and the injured nerve of each rat was removed. Results There were statistically-significant differences between the groups regarding the measurements of the after-treatment values of stimulus threshold (p < 0.05). The best improvement in electrophysiological measurement and histopathological evaluation was found in Group 4 (CHT-PRP). Conclusion Chitosan gel has a positive effect on nerve healing and applying it along with PRP can enhance the effect of chitosan.
- 6 May 2021
- Published by Springer Nature in European Archives of Oto-Rhino-Laryngology
- Vol. 279 (2) , 987-994
Effects of chitosan and platelet-rich plasma on facial nerve regeneration in an animal model
Purpose There is still no widely-accepted local agent proven to be effective in nerve regeneration. We aimed to investigate the effects of chitosan gel and platelet-rich plasma Materials and methods Electrophysiological measurements were performed before and immediately after injury. The injured nerves were covered with spongostan impregnated with the following agents: Group 1 (Control Group): Saline at a dose of 50 µl; Group 2: Chitosan (CHT) at a dose of 50 µl; Group 3: PRP at a dose of 50 ml; and Group 4: a solution of CHT with PRP (1:1). The final measurements were performed after 3 weeks and the injured nerve of each rat was removed. Results There were statistically-significant differences between the groups regarding the measurements of the after-treatment values of stimulus threshold (p < 0.05). The best improvement in electrophysiological measurement and histopathological evaluation was found in Group 4 (CHT-PRP). Conclusion Chitosan gel has a positive effect on nerve healing and applying it along with PRP can enhance the effect of chitosan.