Isabella Caixeta Winter
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Isabella Caixeta Winter has a total of 72 co-authors. Here are the top co-authors by number of shared publications:
- Jorge Tiburcio Barbosa de Lima
Department of Veterinary Clinical Science UNESP‐São Paulo State University Botucatu SP Brazil
7 shared publications - Armando Mattos Carvalho
EQUINOVA Research Group, Department of Veterinary Medicine and Surgery, Veterinary School, Federal University of Minas Gerais (UFMG), Belo Horizonte 31270-901, Brazil
4 shared publications - Rafael Resende Faleiros
EQUINOVA Research Group, Department of Veterinary Medicine and Surgery, Veterinary School, Federal University of Minas Gerais (UFMG), Belo Horizonte 31270-901, Brazil
4 shared publications - Lara Nunes Sousa
EQUINOVA Research Group, Department of Veterinary Medicine and Surgery, Veterinary School, Federal University of Minas Gerais (UFMG), Belo Horizonte 31270-901, Brazil
3 shared publications - Antonio Catunda Pinho Neto2 shared publications
- Heloísa de Paula Pedroza2 shared publications
Latest Publications
- 5 December 2024
- Published by Elsevier in Journal of Equine Veterinary Science
- Vol. 144, 105253
Bilateral coxofemoral dysplasia in a Mangalarga Marchador foal
- 5 December 2024
- Published by Elsevier in Journal of Equine Veterinary Science
- Vol. 144, 105253
Bilateral coxofemoral dysplasia in a Mangalarga Marchador foal
- Open Access
Lidocaine’s Ineffectiveness in Mitigating Lipopolysaccharide-Induced Pain and Peristaltic Effects in Horses
The present study involved seven horses in a randomized crossover clinical trial to evaluate the effect of lidocaine on horses with induced endotoxemia. Horses received intravenous lidocaine (1.5 mg/kg bolus, followed by 0.05 mg/kg bwt/min) or placebo (0.9% sodium chloride at the same manner) one hour before LPS administration (0.03 μg/kg, IV infusion over 30 min). We monitored clinic and hematologic parameters, abdominal auscultation, ultrasound, and pain over time. No relevant clinical differences existed between treatments regarding peristalsis, abdominal pain, or any other parameters before and after endotoxemia induction. These findings do not support the clinical use of lidocaine to mitigate abdominal pain and intestinal hypomotility promoted by endotoxemia in horses.
Open AccessLidocaine’s Ineffectiveness in Mitigating Lipopolysaccharide-Induced Pain and Peristaltic Effects in Horses
The present study involved seven horses in a randomized crossover clinical trial to evaluate the effect of lidocaine on horses with induced endotoxemia. Horses received intravenous lidocaine (1.5 mg/kg bolus, followed by 0.05 mg/kg bwt/min) or placebo (0.9% sodium chloride at the same manner) one hour before LPS administration (0.03 μg/kg, IV infusion over 30 min). We monitored clinic and hematologic parameters, abdominal auscultation, ultrasound, and pain over time. No relevant clinical differences existed between treatments regarding peristalsis, abdominal pain, or any other parameters before and after endotoxemia induction. These findings do not support the clinical use of lidocaine to mitigate abdominal pain and intestinal hypomotility promoted by endotoxemia in horses.
- Open Access
- 14 February 2023
- Published by Research, Society and Development in Research, Society and Development
- Vol. 12 (3)
Efeitos sedativos e cardiorrespiratórios da detomidina associada ou não ao diazepam em equinos submetidos ao exame odontológico
A sedação para o exame odontológico, em estação, nos equinos é essencial para facilitar o manejo e garantir um exame de excelência. O presente estudo objetivou avaliar se o diazepam associado à detomidina potencializaria a sedação do agonista α2 (detomidina), principalmente pela redução do movimento da língua e mastigação sem excessiva desestabilização. Foram examinados 12 equinos adultos de diferentes idades, raças e sexos submetidos a correção dos arcos dentários e distribuídos aleatoriamente entre dois tratamentos: detomidina (20 µg.kg-1, IV) e diazepam (20 µg.kg-1, IV) (DD; n=6) ou detomidina (20 µg.kg-1, IV) e solução salina de NaCl 0,9% (DS; n=6). Foram avaliados o relaxamento e a exposição da língua, frequência cardíaca, intervalo PR, frequência respiratória, pressão arterial sistólica, temperatura retal, bloqueios atrioventriculares de segundo grau, grau de ataxia, movimento da cabeça, em nove momentos. E a distância da cabeça ao solo (HHAG) foram avaliadas em três momentos. Sempre que houve necessidade de aumentar a sedação, foi administrado um bolus de detomidina adicional (5µg.kg-1, IV). Todos os tratamentos proporcionaram sedação e relaxamento muscular. Foram observadas diferenças entre os momentos para o relaxamento da língua (língua VAS mm) e isto foi melhor observado em T7 para o tratamento DD e T5 para o tratamento DS e manteve-se significativamente inferior à linha de base durante todo o tempo avaliado. O presente estudo sugere que a detomidina forneceu sedação adequada em cavalos submetidos ao exame odontológico mas não há necessidade de utilizar o diazepam da forma proposta porque não foi encontrada qualquer diferença entre tratamentos para qualquer variável estudada. A adição de diazepam não melhorou a sedação e nem diminuiu o movimento da língua.
- 14 February 2023
- Published by Research, Society and Development in Research, Society and Development
- Vol. 12 (3)
Open AccessEfeitos sedativos e cardiorrespiratórios da detomidina associada ou não ao diazepam em equinos submetidos ao exame odontológico
A sedação para o exame odontológico, em estação, nos equinos é essencial para facilitar o manejo e garantir um exame de excelência. O presente estudo objetivou avaliar se o diazepam associado à detomidina potencializaria a sedação do agonista α2 (detomidina), principalmente pela redução do movimento da língua e mastigação sem excessiva desestabilização. Foram examinados 12 equinos adultos de diferentes idades, raças e sexos submetidos a correção dos arcos dentários e distribuídos aleatoriamente entre dois tratamentos: detomidina (20 µg.kg-1, IV) e diazepam (20 µg.kg-1, IV) (DD; n=6) ou detomidina (20 µg.kg-1, IV) e solução salina de NaCl 0,9% (DS; n=6). Foram avaliados o relaxamento e a exposição da língua, frequência cardíaca, intervalo PR, frequência respiratória, pressão arterial sistólica, temperatura retal, bloqueios atrioventriculares de segundo grau, grau de ataxia, movimento da cabeça, em nove momentos. E a distância da cabeça ao solo (HHAG) foram avaliadas em três momentos. Sempre que houve necessidade de aumentar a sedação, foi administrado um bolus de detomidina adicional (5µg.kg-1, IV). Todos os tratamentos proporcionaram sedação e relaxamento muscular. Foram observadas diferenças entre os momentos para o relaxamento da língua (língua VAS mm) e isto foi melhor observado em T7 para o tratamento DD e T5 para o tratamento DS e manteve-se significativamente inferior à linha de base durante todo o tempo avaliado. O presente estudo sugere que a detomidina forneceu sedação adequada em cavalos submetidos ao exame odontológico mas não há necessidade de utilizar o diazepam da forma proposta porque não foi encontrada qualquer diferença entre tratamentos para qualquer variável estudada. A adição de diazepam não melhorou a sedação e nem diminuiu o movimento da língua.
- Open Access
- 1 June 2022
- Published by FapUNIFESP (SciELO) in Arquivo Brasileiro de Medicina Veterinária e Zootecnia
- Vol. 74 (3) , 437-445
Mammary gland secretion pH and electrolytes in prepartum Mangalarga Marchador mares
The objective of this study was to determine pH and the concentrations of Calcium (Ca2+), Magnesium (Mg2+), Chloride (Cl-), Sodium (Na+), Potassium (K+) and Calcium (Ca2+) in the mammary gland secretion in pre-foaling Mangalarga Marchador (MM) mares to determine the best method to predict parturition in the breed. Forty-two pregnant MM mares were evaluated once daily from 310 days of gestation until parturition. Mammary gland secretion pH, measured by pH meter and pH paper strip, Mg2+, Ca2+ and Cl- levels significantly changed during the last 10 days prior to parturition (p<0.05). The lowest pH mean value (pH meter=6.67±0.42; pH strip=6.23±0.53) and significantly higher mean concentrations of Ca2+ (12.6±5.8mmol/L) and Mg2+ (10.93±3.66mmol/L) were obtained 24 hours prior to foaling (p<0.0001). Chloride levels reduced significantly 8 days prior to parturition (p<0.0001) but remained unchanged until the due date. Mammary gland pH secretion, measured by pH meter and pH paper strip, was effective to predict parturition. Quantitative pH values obtained with the pH meter had a greater accuracy in comparison to pH paper strips, but a strong correlation was found between both methods. Calcium and magnesium were the only electrolytes that changed in concentration immediately prior to parturition and are better indicators of when not to expect foaling.
- 1 June 2022
- Published by FapUNIFESP (SciELO) in Arquivo Brasileiro de Medicina Veterinária e Zootecnia
- Vol. 74 (3) , 437-445
Open AccessMammary gland secretion pH and electrolytes in prepartum Mangalarga Marchador mares
The objective of this study was to determine pH and the concentrations of Calcium (Ca2+), Magnesium (Mg2+), Chloride (Cl-), Sodium (Na+), Potassium (K+) and Calcium (Ca2+) in the mammary gland secretion in pre-foaling Mangalarga Marchador (MM) mares to determine the best method to predict parturition in the breed. Forty-two pregnant MM mares were evaluated once daily from 310 days of gestation until parturition. Mammary gland secretion pH, measured by pH meter and pH paper strip, Mg2+, Ca2+ and Cl- levels significantly changed during the last 10 days prior to parturition (p<0.05). The lowest pH mean value (pH meter=6.67±0.42; pH strip=6.23±0.53) and significantly higher mean concentrations of Ca2+ (12.6±5.8mmol/L) and Mg2+ (10.93±3.66mmol/L) were obtained 24 hours prior to foaling (p<0.0001). Chloride levels reduced significantly 8 days prior to parturition (p<0.0001) but remained unchanged until the due date. Mammary gland pH secretion, measured by pH meter and pH paper strip, was effective to predict parturition. Quantitative pH values obtained with the pH meter had a greater accuracy in comparison to pH paper strips, but a strong correlation was found between both methods. Calcium and magnesium were the only electrolytes that changed in concentration immediately prior to parturition and are better indicators of when not to expect foaling.
- Open Access
- 1 January 2021
- Published by FapUNIFESP (SciELO) in Ciência Rural
- Vol. 51 (8)
Clostridioides (Clostridium) difficile-associated diarrhea in equine in Minas Gerais, Brazil: clinical and microbiological characterization of six cases
Clostridioides (Clostridium) difficile is the main causative agent of antimicrobial-related diarrhea in humans and a major pathogen-associated enteric disorder in foals and adult horses. Moreover, studies have suggested that animals are a possible reservoir of toxigenic C. difficile strains for humans. Despite this known importance, the epidemiology of C. difficile infection (CDI) in equine is still largely unknown. Therefore, this study described six cases of equine CDI occurring in Minas Gerais, Brazil, including the characterization of the isolates. All but one equine included in this research developed CDI after antimicrobial therapy, three of which occurred during hospitalization. Coinfection with Salmonella Heidelberg and S. Infantis was detected in three cases, making the antimicrobial treatment challenging. All animals recovered after metronidazole administration. All C. difficile isolates were susceptible to metronidazole and vancomycin, while three were resistant to moxifloxacin and two were resistant to clindamycin. The isolates were classified as RT126 (n = 4), RT078 (n = 1), and RT014/020 (n = 1), all previously reported infecting humans and animals worldwide.
- 1 January 2021
- Published by FapUNIFESP (SciELO) in Ciência Rural
- Vol. 51 (8)
Open AccessClostridioides (Clostridium) difficile-associated diarrhea in equine in Minas Gerais, Brazil: clinical and microbiological characterization of six cases
Clostridioides (Clostridium) difficile is the main causative agent of antimicrobial-related diarrhea in humans and a major pathogen-associated enteric disorder in foals and adult horses. Moreover, studies have suggested that animals are a possible reservoir of toxigenic C. difficile strains for humans. Despite this known importance, the epidemiology of C. difficile infection (CDI) in equine is still largely unknown. Therefore, this study described six cases of equine CDI occurring in Minas Gerais, Brazil, including the characterization of the isolates. All but one equine included in this research developed CDI after antimicrobial therapy, three of which occurred during hospitalization. Coinfection with Salmonella Heidelberg and S. Infantis was detected in three cases, making the antimicrobial treatment challenging. All animals recovered after metronidazole administration. All C. difficile isolates were susceptible to metronidazole and vancomycin, while three were resistant to moxifloxacin and two were resistant to clindamycin. The isolates were classified as RT126 (n = 4), RT078 (n = 1), and RT014/020 (n = 1), all previously reported infecting humans and animals worldwide.
- 1 January 2021
- Published by Even3
MELHORIAS FÍSICO-QUÍMICAS NO LÍQUIDO SINOVIAL DE EQUINOS APÓS SUPLEMENTAÇÃO DA DIETA COM UM COMPOSTO MINERAL ORGÂNICO
Anais do Simpósio Internacional do Cavalo Atleta (SIMCAV) (978-65-5941-211-2) - Melhorias Físico-Químicas No Líquido Sinovial De Equinos Após Suplementação Da Dieta Com Um Composto Mineral Orgânico
- 1 January 2021
- Published by Even3
MELHORIAS FÍSICO-QUÍMICAS NO LÍQUIDO SINOVIAL DE EQUINOS APÓS SUPLEMENTAÇÃO DA DIETA COM UM COMPOSTO MINERAL ORGÂNICO
Anais do Simpósio Internacional do Cavalo Atleta (SIMCAV) (978-65-5941-211-2) - Melhorias Físico-Químicas No Líquido Sinovial De Equinos Após Suplementação Da Dieta Com Um Composto Mineral Orgânico
- 1 January 2021
- Published by Even3
ESTUDO PRÉ-CLÍNICO DO EFEITO PROCINÉTICO DA BROMOPRIDA EM EQUINOS
Anais do Simpósio Internacional do Cavalo Atleta (SIMCAV) (978-65-5941-211-2) - Estudo Pré-Clínico Do Efeito Procinético Da Bromoprida Em Equinos
- 1 January 2021
- Published by Even3
ESTUDO PRÉ-CLÍNICO DO EFEITO PROCINÉTICO DA BROMOPRIDA EM EQUINOS
Anais do Simpósio Internacional do Cavalo Atleta (SIMCAV) (978-65-5941-211-2) - Estudo Pré-Clínico Do Efeito Procinético Da Bromoprida Em Equinos
- 1 January 2021
- Published by Even3
AFECÇÕES ODONTOLÓGICAS EM EQUÍDEOS GERIATRAS: ESTUDO RETROSPECTIVO
Anais do Simpósio Internacional do Cavalo Atleta (SIMCAV) (978-65-5941-211-2) - Afecções Odontológicas Em Equídeos Geriatras: Estudo Retrospectivo
- 1 January 2021
- Published by Even3
AFECÇÕES ODONTOLÓGICAS EM EQUÍDEOS GERIATRAS: ESTUDO RETROSPECTIVO
Anais do Simpósio Internacional do Cavalo Atleta (SIMCAV) (978-65-5941-211-2) - Afecções Odontológicas Em Equídeos Geriatras: Estudo Retrospectivo
- 1 January 2021
- Published by Even3
INFLAMAÇÃO NEUTROFÍLICA TRANSMURAL NO CÓLON MENOR DE EQUINOS SUBMETIDOS A INJÚRIA DE ISQUEMIA E REPERFUSÃO
Anais do Simpósio Internacional do Cavalo Atleta (SIMCAV) (978-65-5941-211-2) - Inflamação Neutrofílica Transmural No Cólon Menor De Equinos Submetidos A Injúria De Isquemia E Reperfusão
- 1 January 2021
- Published by Even3
INFLAMAÇÃO NEUTROFÍLICA TRANSMURAL NO CÓLON MENOR DE EQUINOS SUBMETIDOS A INJÚRIA DE ISQUEMIA E REPERFUSÃO
Anais do Simpósio Internacional do Cavalo Atleta (SIMCAV) (978-65-5941-211-2) - Inflamação Neutrofílica Transmural No Cólon Menor De Equinos Submetidos A Injúria De Isquemia E Reperfusão