Megan L. Rasmussen
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Megan L. Rasmussen has a total of 31 co-authors. Here are the top co-authors by number of shared publications:
- Vivian Gama
Department of Cell and Developmental Biology Vanderbilt University Nashville Tennessee USA
6 shared publications - Allison R. Greenplate
Institute for Immunology & Immune Health (I3H), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
3 shared publications Brian K. Oberholtzer
3 shared publications- Caroline E. Roe
Department of Pediatrics-Neurology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA
3 shared publications Daniel D. McClanahan
3 shared publications- Deon Bryant Doxie
Winship Cancer Institute of Emory University, Atlanta, USA
3 shared publications
Latest Publications
- Open Access
- 3 April 2023
- Published by American Association for Cancer Research (AACR)
Supplementary Table 2 from Computational Immune Monitoring Reveals Abnormal Double-Negative T Cells Present across Human Tumor Types
Supplementary table containing the mass cytometry staining panels used in this manuscript.
- 3 April 2023
- Published by American Association for Cancer Research (AACR)
Open AccessSupplementary Table 2 from Computational Immune Monitoring Reveals Abnormal Double-Negative T Cells Present across Human Tumor Types
Supplementary table containing the mass cytometry staining panels used in this manuscript.
- Open Access
- 1 March 2018
- Published by Elsevier in Stem Cell Reports
- Vol. 10 (3) , 684-692
A Non-apoptotic Function of MCL-1 in Promoting Pluripotency and Modulating Mitochondrial Dynamics in Stem Cells
- 1 March 2018
- Published by Elsevier in Stem Cell Reports
- Vol. 10 (3) , 684-692
Open AccessA Non-apoptotic Function of MCL-1 in Promoting Pluripotency and Modulating Mitochondrial Dynamics in Stem Cells
- Open Access
Wnt Signaling and Its Impact on Mitochondrial and Cell Cycle Dynamics in Pluripotent Stem Cells
The core transcriptional network regulating stem cell self-renewal and pluripotency remains an intense area of research. Increasing evidence indicates that modified regulation of basic cellular processes such as mitochondrial dynamics, apoptosis, and cell cycle are also essential for pluripotent stem cell identity and fate decisions. Here, we review evidence for Wnt regulation of pluripotency and self-renewal, and its connections to emerging features of pluripotent stem cells, including (1) increased mitochondrial fragmentation, (2) increased sensitivity to cell death, and (3) shortened cell cycle. We provide a general overview of the stem cell–specific mechanisms involved in the maintenance of these uncharacterized hallmarks of pluripotency and highlight potential links to the Wnt signaling pathway. Given the physiological importance of stem cells and their enormous potential for regenerative medicine, understanding fundamental mechanisms mediating the crosstalk between Wnt, organelle-dynamics, apoptosis, and cell cycle will be crucial to gain insight into the regulation of stemness.
Open AccessWnt Signaling and Its Impact on Mitochondrial and Cell Cycle Dynamics in Pluripotent Stem Cells
The core transcriptional network regulating stem cell self-renewal and pluripotency remains an intense area of research. Increasing evidence indicates that modified regulation of basic cellular processes such as mitochondrial dynamics, apoptosis, and cell cycle are also essential for pluripotent stem cell identity and fate decisions. Here, we review evidence for Wnt regulation of pluripotency and self-renewal, and its connections to emerging features of pluripotent stem cells, including (1) increased mitochondrial fragmentation, (2) increased sensitivity to cell death, and (3) shortened cell cycle. We provide a general overview of the stem cell–specific mechanisms involved in the maintenance of these uncharacterized hallmarks of pluripotency and highlight potential links to the Wnt signaling pathway. Given the physiological importance of stem cells and their enormous potential for regenerative medicine, understanding fundamental mechanisms mediating the crosstalk between Wnt, organelle-dynamics, apoptosis, and cell cycle will be crucial to gain insight into the regulation of stemness.