Shimaa Hassan AbdelAziz Soliman
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Shimaa Hassan AbdelAziz Soliman has a total of 2 co-authors. Here are the top co-authors by number of shared publications:
- Arturo Orlacchio
Department of Cancer Biology and Genetics, College of Medicine, The Ohio State University, Columbus, OH 43210, USA
1 shared publication - Fabio Verginelli
Department of Pharmacy, G. D’Annunzio University of Chieti-Pescara, 66100 Chieti, Italy
1 shared publication
Latest Publications
- Open Access
- 30 May 2021
- Published by MDPI AG in Microorganisms
- Vol. 9 (6) , 1179
Viral Manipulation of the Host Epigenome as a Driver of Virus-Induced Oncogenesis
Tumorigenesis due to viral infection accounts for a high fraction of the total global cancer burden (15–20%) of all human cancers. A comprehensive understanding of the mechanisms by which viral infection leads to tumor development is extremely important. One of the main mechanisms by which viruses induce host cell proliferation programs is through controlling the host’s epigenetic machinery. In this review, we dissect the epigenetic pathways through which oncogenic viruses can integrate their genome into host cell chromosomes and lead to tumor progression. In addition, we highlight the potential use of drugs based on histone modifiers in reducing the global impact of cancer development due to viral infection.
- 30 May 2021
- Published by MDPI AG in Microorganisms
- Vol. 9 (6) , 1179
Open AccessViral Manipulation of the Host Epigenome as a Driver of Virus-Induced Oncogenesis
Tumorigenesis due to viral infection accounts for a high fraction of the total global cancer burden (15–20%) of all human cancers. A comprehensive understanding of the mechanisms by which viral infection leads to tumor development is extremely important. One of the main mechanisms by which viruses induce host cell proliferation programs is through controlling the host’s epigenetic machinery. In this review, we dissect the epigenetic pathways through which oncogenic viruses can integrate their genome into host cell chromosomes and lead to tumor progression. In addition, we highlight the potential use of drugs based on histone modifiers in reducing the global impact of cancer development due to viral infection.