Freya Wenzel
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Freya Wenzel has a total of 5 co-authors. Here are the top co-authors by number of shared publications:
- Anne Pralong
University of Cologne, Faculty of Medicine and University Hospital, Department of Palliative Medicine, Cologne, Germany
1 shared publication - Christof Scheid
University of Cologne, Cologne, Germany
1 shared publication - Marco Herling
Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany
1 shared publication - Steffen T. Simon
University of Cologne, Faculty of Medicine and University Hospital, Department of Palliative Medicine, Cologne, Germany
1 shared publication - Udo Holtick
University of Cologne, Faculty of Medicine and University Hospital, Centre for Integrated Oncology Aachen-Bonn-Cologne-Duesseldorf (CIO ABCD), Cologne, Germany
1 shared publication
Latest Publications
- Open Access
Burden and Needs of Patients with Severe GvHD from the Supportive and Palliative Care Perspective—A Literature Review
Graft-versus-host disease (GvHD) is a frequent, and often life-threatening, complication after an allogeneic, hematopoietic stem cell transplantation (allo-SCT). It can appear in an acute or a chronic form and presents different grades of severity. Particularly, the severe forms of GvHD are often responsible for a change of the curative intent for allo-SCT into a palliative goal of care. For this non-systematic review, we conducted a focused literature search in the MEDLINE database via PubMed to examine whether patients with severe forms of GvHD might have special needs and burdens from a supportive and palliative care perspective. To draw a comprehensive picture of this patient group, we included findings on quality of life (QoL) and physical symptoms and function as well as psychological and spiritual well-being. In most domains, patients with severe forms of GvHD showed greater impairment and a higher symptom burden compared to patients with milder forms of GvHD. However, we could not identify any studies that specifically investigated patients with severe forms of GvHD. Further research in this field is necessary to guarantee the highest standard of care for this very special patient group.
Open AccessBurden and Needs of Patients with Severe GvHD from the Supportive and Palliative Care Perspective—A Literature Review
Graft-versus-host disease (GvHD) is a frequent, and often life-threatening, complication after an allogeneic, hematopoietic stem cell transplantation (allo-SCT). It can appear in an acute or a chronic form and presents different grades of severity. Particularly, the severe forms of GvHD are often responsible for a change of the curative intent for allo-SCT into a palliative goal of care. For this non-systematic review, we conducted a focused literature search in the MEDLINE database via PubMed to examine whether patients with severe forms of GvHD might have special needs and burdens from a supportive and palliative care perspective. To draw a comprehensive picture of this patient group, we included findings on quality of life (QoL) and physical symptoms and function as well as psychological and spiritual well-being. In most domains, patients with severe forms of GvHD showed greater impairment and a higher symptom burden compared to patients with milder forms of GvHD. However, we could not identify any studies that specifically investigated patients with severe forms of GvHD. Further research in this field is necessary to guarantee the highest standard of care for this very special patient group.