Ugurkan Erkayiran

Background: Preterm premature rupture of membranes (PPROM) is a significant complication in pregnancy, often associated with adverse maternal and fetal outcomes. Understanding the relationship between clinical and laboratory parameters at admission and pregnancy outcomes in PPROM cases is essential for effective management and intervention. Methods The study was conducted retrospectively to examine the relationship between clinical and laboratory parameters at the time of admission and the latent period in pregnant women with PPROM. Records of pregnant women diagnosed with PPROM between 2015-2017 in the obstetrics department of a university hospital were reviewed. The patients were grouped according to gestational weeks, clinical parameters at admission were recorded, and their relationships with the latent period were analyzed. Results When the data obtained in the study were analyzed, it was shown that cervical length (p = 0.008) and the gestational week at the time of admission had an effect on the latent period (p

Objective: The study investigated isthmocele rate, residual myometrium thickness, blood loss, and closure lengths by comparing the classical primary continuous(CPCS) and novel technique uterine suturing (NTUS) after caesarian. Design: All patients were divided into two groups according to suture technique. Setting: CPCS was applied to the patients in Group-1, while the NTUS was applied in Group-2 as Z suture on both corners and 8 sutures in the remaining middle part incision closure. Population: A total of 402 C/S patients were included in this single-center prospective clinical study. Main Outcome Measures: Patients in the NTUS group bleed lesser than in the CPCS groups (p<0.0001). Incision length after closure was longer in the CPCS than in the NTUS (p<0.0001). Similarly, the number of sutures we applied was higher in the CPCS (p<0.0001). In the comparison of residual myometrium thickness, the mean values measured 197±50 mm in the NTUS and 146±39 mm in the CPCS (p<0.0001). Results: Residual myometrium thickness showed a negative strong correlation with incision length after closure (r=-0,436; p<0.0001), how many times the needles have been passed (r=-0,423; p<0.0001) and time for suturing (r=-0,237; p<0.0001). NTUS and CPCS groups were similar in comparison to isthmocele. Conclusions: The NTUS, termed Erkayiran’s suture, showed a successful reflection in our surgical cesarean section application compared to the classical suture. Although the occurrence of isthmocele in patients was similar, results were quite successful operationally in terms of both minimal blood loss and increased residual myometrium thickness.

Background: Considering the presence of an inflammatory process in the pathogenesis of endometriosis, anti-inflammatory agents could be an alternative option. The study aimed to elucidate the curative efficacy of Ursodeoxycholic acid (UDCA) on the experimental rat model of endometriosis. Methods: This experimental research included a total of 60 mature female Wistar albino rats (250 ± 50 g) with no pregnancy. They were grouped as Standard (n: 20), Laparoscopic Pretreatment (n: 10), Laparoscopic Posttreatment (Sham) (n: 10), UDCA-Pretreatment (n: 10) and UDCA-Posttreatment (n: 10). Transforming growth factor β1 (TGF-β1), matrix metallo-proteinases-2 (MMP-2), Tissue inhibitor of metalloproteinase-1 (TIMP-1), Tumor necrosis factor-α (TNF-α) were analyzed. Results: In the UDCA post-treatment group, endometriotic focal volume (43.3 ± 24.04 mm3) was lower than the pre-treatment values (165.7 ± 21.7 mm3) (p = 0.005). There was no significant change UDCA group before and after the treatment in terms of MMP-2, TGF-β1, TIMP-1 and TNF-α levels (p > 0.05). Comparing the posttreatment values of the Sham srugery group and the UDCA group, while the endometriotic focal volume was 251 ± 51 mm3 in the Sham group, it decreased to 43.3 ± 24 mm3 in the UDCA (p < 0.0001). Histological scoring decreased from 2.6 ± 0.51 to 1 ± 0.81 after the treatment (p = 0.001). Conclusions: The pre-treatment laparotomy group exhibited elevated TNF-α levels, indicating an inflammatory response. UDCA treatment reduced endometriotic focal volume and histological scoring, indicating a potential therapeutic benefit.

Citation: Arslanca SB, Sahin O, Erkayıran U, Basarır ZO, Arslanca T. Can Stria Gravidarum Predict Surgical Fluid Loss in Cesarean Section? Dermatol Pract Concept. 2023;13(3):e2023175. DOI: https://doi.org/10.5826/dpc.1303a175 Accepted: November 7, 2022; Published: July 2023 Copyright: ©2023 Arslanca et al. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (BY-NC-4.0), https://creativecommons.org/licenses/by-nc/4.0/, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original authors and source are credited. Funding: None. Competing interests: None. Authorship: All authors have contributed significantly to this publication. Corresponding author: Tufan Arslanca, Department of Gynecologic Oncology, Ankara City Hospital, University of Health Sciences, Ankara, Turkey. ORCID:0000-0001-9686-1603 E-mail: drtufanarslanca@hotmail.com Introduction: Alterations in collagen subtypes and matrix can potentially cause fluid loss in surgery which are important in terms of liqud loss. Objectives: The study aimed to analyze stria gravidarum (SG) and its severity in pregnant who had undergone cesarean section (CS) and to evaluate surgical fluid loss (SFL) that occurred during CS operation. Methods: The research was designed as a prospective clinical cohort study to compare the amount of SFL in the second cesarean section with the severity of SG at 34-37 weeks pregnant (n:308). The severity of SG was evaluated in the preoperative period using the Davey scoring. All patients were defined none, mild stria and severe stria. The SFL was calculated by weighing the pre-and post-operative weights of the sponges. Results: The weight gain (p=0,008) and BMI (p=0,017) gradually increased toward severe SG. In correlation analysis of SFL, a positive correlation was found with Davey (r=0.791; p=0.0001), weight gained during pregnancy (r=0.328;p=0.0001), BMI (r=0.453;p=0.001) and newborn’s weight (r=0.139;p=0.003). In the ROC for the predictability of SG severity on SFL, severe SG showed a potential for SFL with %95.1 specificity and %93.2 sensitivity at 791 cut-offs (Area Under the Curve:0,987; p=0.00001; %95 Confidence Interval: 0.977-0.997). Conclusion: The SG severity and SFL showed a very strong relationship, which was a very important finding that would affect the approach of the surgeons to the patients with SG in terms of fluid loss in CS. Keywords : Stria gravidarum, surgical fluid loss, cesarean section, Davey score This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Aim: To determine the levels of perlecan, which contributes to autophagy inhibition and angiogenesis, in severe and mild preeclamptic women. Material and Method: A total of 89 patients including severe preeclampsia, group 1 (n: 30), mild preeeclampsia, group 2 (n: 30) and control group, group 3 (n: 29) were included in the study. Results: All three groups were evaluated in terms of perlecan levels. Perlecan level in group 1 was determined at higher levels than other groups, and this level difference was statistically significant compared to the other two groups (p

Objectives: Nosocomial outbreaks of infection originating from ultrasound probes and contaminated coupling gels have been reported. It was reported that the ultrasound probe, if cultured after routine scanning of intact skin, may become colonized with skin flora.Methods: Culture swabs from 22 probes of the 9 ultrasound machines and from the gels in the 10 gel folders were taken. All swabs taken from probe head, probe holder and the coupling gel in the folder at the beginning of the day were cultured. After fifth scanning and after wiping off the gel with a dry, nonsterile paper towel, cultures were again obtained from probe head and probe holder.Results: A total of 98 culture results were included of which 42.8% were positive for bacterial growth. The rate of bacterial contamination from probes at morning before the start of examination and after scanning were 34.1% and 56.8%, respectively and this difference was statistically significant (p = 0.023). Conclusions: We think that using nonsterile, dry, soft and absorbent paper towel after each procedure, could be inadequate for disinfection of probe head. Especially, good hand hygiene could decrease the rate of growth of bacterial colony at probe handle.