Hong Seok Shim
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Hong Seok Shim has a total of 39 co-authors. Here are the top co-authors by number of shared publications:
- Ronald Anthony DePinho
Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, USA
2 shared publications Adam T. Boutin
Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
1 shared publicationAndrea Santoni
Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX 77030
1 shared publicationAndrew DuPont
Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030
1 shared publicationAsha S. Multani
Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030
1 shared publicationAsif Rashid
Division of Pathology/Lab Medicine, Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030
1 shared publication
Latest Publications
- 12 July 2021
- Published by National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 118 (29)
Telomere dysfunction instigates inflammation in inflammatory bowel disease
Significance: Inflammatory bowel disease (IBD) is a chronic debilitating condition with limited treatment options. Recently, we found that telomerase reactivation can ameliorate intestinal inflammation in a mouse model of IBD through the regulation of the YAP1/pro-IL-18 axis. This study aims to validate the therapeutic potential of this axis genetically and with the use of small molecule activators and inhibitors in the intestinal epithelium of IBD patients.
- 12 July 2021
- Published by National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 118 (29)
Telomere dysfunction instigates inflammation in inflammatory bowel disease
Significance: Inflammatory bowel disease (IBD) is a chronic debilitating condition with limited treatment options. Recently, we found that telomerase reactivation can ameliorate intestinal inflammation in a mouse model of IBD through the regulation of the YAP1/pro-IL-18 axis. This study aims to validate the therapeutic potential of this axis genetically and with the use of small molecule activators and inhibitors in the intestinal epithelium of IBD patients.