Alisa Malyavko
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The organizations/institutes from the scholar's latest article
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Research Interests
Alisa Malyavko has a total of 89 co-authors. Here are the top co-authors by number of shared publications:
- Sean Tabaie
Department of Orthopedics, Nationwide Childrens Hospital, Columbus, USA
10 shared publications - Theodore Quan
George Washington University School of Medicine, Washington, DC, USA
7 shared publications Alex Gu
Department of Orthopaedic Surgery, George Washington University Hospital, Washington, District of Columbia
4 shared publications- Alex Gu
Department of Orthopaedic Surgery, The George Washington University School of Medicine and Health Sciences, Washington, DC algu@.gwu.edu
4 shared publications Amil R. Agarwal
From the Department of Orthopaedic Surgery, George Washington University, Washington, DC (Dr. Malyavko and Agarwal), and the Johns Hopkins Department of Orthopaedic Surgery, Adult Reconstruction Division, Baltimore, MD (Dr. Mikula, Dr. Best, and Dr. Srikumaran)
3 shared publications- Dayun Yan
Department of Mechanical and Aerospace Engineering, George Washington University, Washington, DC 20052, USA
3 shared publications
Latest Publications
- Open Access
- 9 November 2026
- Published by BMJ in Journal for ImmunoTherapy of Cancer
- Vol. 14  (11) , e015860
Immune cell atlas reveals mechanisms of immune evasion and LAG-3 as a novel target in mouse models of breast cancer metastasis
- 9 November 2026
- Published by BMJ in Journal for ImmunoTherapy of Cancer
- Vol. 14  (11) , e015860
Open AccessImmune cell atlas reveals mechanisms of immune evasion and LAG-3 as a novel target in mouse models of breast cancer metastasis
- 3 December 2024
- Published by Wolters Kluwer Health in Journal of the American Academy of Orthopaedic Surgeons
- Vol. 33  (7) , 362-369
Shoulder Arthroplasty Patients Are Underscreened for Osteoporosis
Introduction: Osteoporosis screening and subsequent treatment has been shown to be efficacious in decreasing the rates of fragility fractures and periprosthetic fractures (PPF). However, current screening and treatment rates are low. This study aims to determine (1) the prevalence of total shoulder arthroplasty (TSA) patients who meet criteria for osteoporosis screening, (2) the prevalence of those screened, and (3) the 5-year cumulative incidence of fragility fracture (FF) and periprosthetic fractures (PPF). Methods: The PearlDiver database was used to identify all patients older than 50 years who underwent TSA. Guidelines from the American Association of Clinical Endocrinologists were used to stratify patients into “high risk” and “low risk” of osteoporosis cohorts using International Classification of Disease codes for various risk factors. The prevalence of osteoporosis screening using dual-energy x-ray absorptiometry (DXA) scan was analyzed, and the 5-year cumulative incidence of FF and PPF was calculated between the “low-risk” and “high-risk” groups using Kaplan-Meier analysis. Results: In total, 66,140 (65.5%) who underwent TSA were considered “high risk” for osteoporosis. Of the “high-risk” patients, 11.7% patients received routine osteoporosis screening preoperatively. Within 5 years, “high-risk” TSA patients had markedly higher cumulative incidence for PPF (HR: 1.4; 95% CI: 1.0-1.9; P = 0.037) and FF (HR: 2.42; 95% CI: 2.1-2.8; P < 0.001) when compared with those at “low risk”. Discussion: There is a high prevalence of osteoporosis among patients undergoing TSA but a low rate of routine osteoporosis screening in this cohort. Patients with osteoporosis who are categorized as “high risk” have an increased rate of fragility fractures and PPF. Therefore, there is an opportunity to increase appropriate osteoporosis screening and management in this cohort, which may affect future risk of FF and periprosthetic fracture. Level of evidence: III
- 3 December 2024
- Published by Wolters Kluwer Health in Journal of the American Academy of Orthopaedic Surgeons
- Vol. 33  (7) , 362-369
Shoulder Arthroplasty Patients Are Underscreened for Osteoporosis
Introduction: Osteoporosis screening and subsequent treatment has been shown to be efficacious in decreasing the rates of fragility fractures and periprosthetic fractures (PPF). However, current screening and treatment rates are low. This study aims to determine (1) the prevalence of total shoulder arthroplasty (TSA) patients who meet criteria for osteoporosis screening, (2) the prevalence of those screened, and (3) the 5-year cumulative incidence of fragility fracture (FF) and periprosthetic fractures (PPF). Methods: The PearlDiver database was used to identify all patients older than 50 years who underwent TSA. Guidelines from the American Association of Clinical Endocrinologists were used to stratify patients into “high risk” and “low risk” of osteoporosis cohorts using International Classification of Disease codes for various risk factors. The prevalence of osteoporosis screening using dual-energy x-ray absorptiometry (DXA) scan was analyzed, and the 5-year cumulative incidence of FF and PPF was calculated between the “low-risk” and “high-risk” groups using Kaplan-Meier analysis. Results: In total, 66,140 (65.5%) who underwent TSA were considered “high risk” for osteoporosis. Of the “high-risk” patients, 11.7% patients received routine osteoporosis screening preoperatively. Within 5 years, “high-risk” TSA patients had markedly higher cumulative incidence for PPF (HR: 1.4; 95% CI: 1.0-1.9; P = 0.037) and FF (HR: 2.42; 95% CI: 2.1-2.8; P < 0.001) when compared with those at “low risk”. Discussion: There is a high prevalence of osteoporosis among patients undergoing TSA but a low rate of routine osteoporosis screening in this cohort. Patients with osteoporosis who are categorized as “high risk” have an increased rate of fragility fractures and PPF. Therefore, there is an opportunity to increase appropriate osteoporosis screening and management in this cohort, which may affect future risk of FF and periprosthetic fracture. Level of evidence: III
- 17 February 2023
- Published by Elsevier in The Journal of Arthroplasty
- Vol. 38  (8) , 1591-1596.e3
Diagnostic and Invasive Colonoscopy Are Not Risk Factors for Revision Surgery Due to Periprosthetic Joint Infection
- 17 February 2023
- Published by Elsevier in The Journal of Arthroplasty
- Vol. 38  (8) , 1591-1596.e3
Diagnostic and Invasive Colonoscopy Are Not Risk Factors for Revision Surgery Due to Periprosthetic Joint Infection
- Open Access
- 1 January 2023
- Published by Wolters Kluwer Health in JBJS Open Access
- Vol. 8  (1)
An Evaluation of Resources Available to Learn About Orthopaedic Surgery Residency Programs
Introduction: Orthopaedic surgery is one of the most competitive residencies to match into, and understanding what information is useful for applicants can reduce the number of programs applied to. The purpose of this study was to (1) determine which residency recruitment resources influence where applicants apply and how they rank programs, (2) identify what information would be most helpful for applicants to learn about programs, and (3) determine whether orthopaedic surgery applicants have preferential solutions to improve the application process. Methods: Medical students who applied to the orthopaedic surgery residency program at the senior author's institution during the 2021-2022 application cycle were invited to participate in this study. The anonymous Qualtrics survey covered several domains of demographics and questions about recruitment resources (e.g., residency websites, in-person away rotations, rankings, and databases with information about orthopaedic surgery programs). Results: Of the 216 survey respondents, 77 (35.6%) identified as female and 132 (61.1%) as male. Twenty-four (11.1%) respondents were the first in their family to graduate from an undergraduate program, and 47 (21.8%) applicants had a physician in their immediate family. Survey respondents selected in-person away rotations as the most influential factor in deciding where to apply (n = 97) and how to rank programs (n = 117). Regarding the residency match, 152 survey respondents (70.4%) would like interview caps, 128 (59.3%) would like an increase in program information available on residency databases, and 120 (55.5%) would like application caps. Discussion: Medical students applying to orthopaedic surgery residency programs found in-person away rotations to be most influential on which programs they applied to. Applicants would like more transparency during the application process to make better informed decisions when applying to and ranking programs. Residency program directors can apply these preferences to facilitate a more equitable process for all students applying to orthopaedic surgery. Level of Evidence: VI
- 1 January 2023
- Published by Wolters Kluwer Health in JBJS Open Access
- Vol. 8  (1)
Open AccessAn Evaluation of Resources Available to Learn About Orthopaedic Surgery Residency Programs
Introduction: Orthopaedic surgery is one of the most competitive residencies to match into, and understanding what information is useful for applicants can reduce the number of programs applied to. The purpose of this study was to (1) determine which residency recruitment resources influence where applicants apply and how they rank programs, (2) identify what information would be most helpful for applicants to learn about programs, and (3) determine whether orthopaedic surgery applicants have preferential solutions to improve the application process. Methods: Medical students who applied to the orthopaedic surgery residency program at the senior author's institution during the 2021-2022 application cycle were invited to participate in this study. The anonymous Qualtrics survey covered several domains of demographics and questions about recruitment resources (e.g., residency websites, in-person away rotations, rankings, and databases with information about orthopaedic surgery programs). Results: Of the 216 survey respondents, 77 (35.6%) identified as female and 132 (61.1%) as male. Twenty-four (11.1%) respondents were the first in their family to graduate from an undergraduate program, and 47 (21.8%) applicants had a physician in their immediate family. Survey respondents selected in-person away rotations as the most influential factor in deciding where to apply (n = 97) and how to rank programs (n = 117). Regarding the residency match, 152 survey respondents (70.4%) would like interview caps, 128 (59.3%) would like an increase in program information available on residency databases, and 120 (55.5%) would like application caps. Discussion: Medical students applying to orthopaedic surgery residency programs found in-person away rotations to be most influential on which programs they applied to. Applicants would like more transparency during the application process to make better informed decisions when applying to and ranking programs. Residency program directors can apply these preferences to facilitate a more equitable process for all students applying to orthopaedic surgery. Level of Evidence: VI
- Open Access
- 30 December 2022
- Published by Springer Nature in Cureus
- Vol. 14  (12) , e33149
Racial Disparities in Outcomes Following Open Treatment of Pediatric Femoral Shaft Fractures
Femoral shaft fractures are a common pediatric injury that can require non-operative or operative management. Several studies have shown that race impacts pain management and a number of emergency department visits in the pediatric femur fracture population. This study aimed to investigate any association between pediatric patient race and number of comorbidities, 30-day postoperative outcomes, and length of stay following open surgical treatment of femoral shaft fractures. Pediatric patients who underwent open treatment of femoral shaft fracture were identified in the National Surgical Quality Improvement Program-Pediatric database from 2012-2019. Patients were categorized into two cohorts: White and underrepresented minority (URM). URM groups included Black or African American, Hispanic, Native American or Alaskan, and Native Hawaiian or Pacific Islander. Demographics, comorbidities, and postoperative complications were compared using bivariate and multivariable regression analyses. Of the 5,284 pediatric patients who underwent open treatment of femoral shaft fracture, 3,650 (69.1%) were White, and 1,634 (30.9%) were URM. Compared to White patients, URM patients were more likely to have a higher American Society of Anesthesiologists score (p=0.012), more likely to have pulmonary comorbidities (p=0.005), require preoperative blood transfusion (p=0.006), and have an increased risk of prolonged hospital stay (OR 2.36; p=0.007). Pediatric URM patients undergoing open treatment of femoral shaft fractures have an increased risk of extended hospital stay postoperatively compared to White patients. As the racial and ethnic constitution of the pediatric population changes, understanding racial and ethnic health disparities will be crucial to providing equitable care to all patients.
- 30 December 2022
- Published by Springer Nature in Cureus
- Vol. 14  (12) , e33149
Open AccessRacial Disparities in Outcomes Following Open Treatment of Pediatric Femoral Shaft Fractures
Femoral shaft fractures are a common pediatric injury that can require non-operative or operative management. Several studies have shown that race impacts pain management and a number of emergency department visits in the pediatric femur fracture population. This study aimed to investigate any association between pediatric patient race and number of comorbidities, 30-day postoperative outcomes, and length of stay following open surgical treatment of femoral shaft fractures. Pediatric patients who underwent open treatment of femoral shaft fracture were identified in the National Surgical Quality Improvement Program-Pediatric database from 2012-2019. Patients were categorized into two cohorts: White and underrepresented minority (URM). URM groups included Black or African American, Hispanic, Native American or Alaskan, and Native Hawaiian or Pacific Islander. Demographics, comorbidities, and postoperative complications were compared using bivariate and multivariable regression analyses. Of the 5,284 pediatric patients who underwent open treatment of femoral shaft fracture, 3,650 (69.1%) were White, and 1,634 (30.9%) were URM. Compared to White patients, URM patients were more likely to have a higher American Society of Anesthesiologists score (p=0.012), more likely to have pulmonary comorbidities (p=0.005), require preoperative blood transfusion (p=0.006), and have an increased risk of prolonged hospital stay (OR 2.36; p=0.007). Pediatric URM patients undergoing open treatment of femoral shaft fractures have an increased risk of extended hospital stay postoperatively compared to White patients. As the racial and ethnic constitution of the pediatric population changes, understanding racial and ethnic health disparities will be crucial to providing equitable care to all patients.
- Open Access
- 24 December 2022
- Published by Springer Nature in Cureus
- Vol. 14  (12) , e32920
Association of Race With Post-operative Complications After Spinal Fusion in Children With Cerebral Palsy
Introduction: Neuromuscular scoliosis in children with cerebral palsy (CP) can lead to debilitating difficulties with pain, ambulation, sitting, and respiratory or cardiac compromise. Spinal fusion can halt deformity progression, though the decision to undergo surgery involves an individualized risk-benefit assessment. The purpose of this study was to evaluate whether race is a risk factor for patients with CP to experience post-operative complications after spinal fusion. Methods: This is a retrospective cohort analysis of a national database. Analyses methods include univariate analyses, multivariate regression models, and other ad-hoc tests. Results: There were 3,081 pediatric patients with CP who underwent spinal fusion. Black patients had an increased risk of experiencing any post-operative complication compared to Caucasians (OR 1.322, 95% CI 1.099-1.590). Both Caucasian(p=0.005) and Black (p<0.001) races were risk factors for experiencing medical complications; Black patients had an increased risk compared to Caucasians (OR 1.373, 95% CI 1.130-1.667). Other races had a greater length of ICU stay than Caucasians (median {Mdn}=3.00 days vs Mdn=2.00, p=0.029), and longer total hospital stays than Caucasian and Black patients (Mdn=9.00 days vs Mdn=6.00 days vs Mdn=6.00 days, p<0.001). Conclusion: Race is an independent risk factor for pediatric patients with CP to experience medical complications following spinal fusion surgery, with Black patients having an increased risk compared to Caucasians. Further, other races were found to have significantly longer ICU and total hospital length of stay. This study is the first to present race as a risk factor for children with CP to experience increased post-operative complications following spinal fusion and will be valuable in understanding their individualized peri-operative courses and risks.
- 24 December 2022
- Published by Springer Nature in Cureus
- Vol. 14  (12) , e32920
Open AccessAssociation of Race With Post-operative Complications After Spinal Fusion in Children With Cerebral Palsy
Introduction: Neuromuscular scoliosis in children with cerebral palsy (CP) can lead to debilitating difficulties with pain, ambulation, sitting, and respiratory or cardiac compromise. Spinal fusion can halt deformity progression, though the decision to undergo surgery involves an individualized risk-benefit assessment. The purpose of this study was to evaluate whether race is a risk factor for patients with CP to experience post-operative complications after spinal fusion. Methods: This is a retrospective cohort analysis of a national database. Analyses methods include univariate analyses, multivariate regression models, and other ad-hoc tests. Results: There were 3,081 pediatric patients with CP who underwent spinal fusion. Black patients had an increased risk of experiencing any post-operative complication compared to Caucasians (OR 1.322, 95% CI 1.099-1.590). Both Caucasian(p=0.005) and Black (p<0.001) races were risk factors for experiencing medical complications; Black patients had an increased risk compared to Caucasians (OR 1.373, 95% CI 1.130-1.667). Other races had a greater length of ICU stay than Caucasians (median {Mdn}=3.00 days vs Mdn=2.00, p=0.029), and longer total hospital stays than Caucasian and Black patients (Mdn=9.00 days vs Mdn=6.00 days vs Mdn=6.00 days, p<0.001). Conclusion: Race is an independent risk factor for pediatric patients with CP to experience medical complications following spinal fusion surgery, with Black patients having an increased risk compared to Caucasians. Further, other races were found to have significantly longer ICU and total hospital length of stay. This study is the first to present race as a risk factor for children with CP to experience increased post-operative complications following spinal fusion and will be valuable in understanding their individualized peri-operative courses and risks.
- Open Access
- 8 December 2022
- Published by Springer Nature in Cureus
- Vol. 14  (12) , e32341
Open Reduction and Internal Fixation of a Pediatric Apophyseal Calcaneus Fracture Using Cannulated Screws: A Case Report
We report a case of a 12-year-old boy who sustained a displaced calcaneal apophysis fracture, which was analogous to a bony avulsion of the insertion of the Achilles tendon, secondary to an awkward landing while jumping at a trampoline park. Treatment with open reduction and internal fixation with cannulated screws provided a novel approach to fixation for this type of fracture in the pediatric population.
- 8 December 2022
- Published by Springer Nature in Cureus
- Vol. 14  (12) , e32341
Open AccessOpen Reduction and Internal Fixation of a Pediatric Apophyseal Calcaneus Fracture Using Cannulated Screws: A Case Report
We report a case of a 12-year-old boy who sustained a displaced calcaneal apophysis fracture, which was analogous to a bony avulsion of the insertion of the Achilles tendon, secondary to an awkward landing while jumping at a trampoline park. Treatment with open reduction and internal fixation with cannulated screws provided a novel approach to fixation for this type of fracture in the pediatric population.
- Open Access
- 29 November 2022
- Published by Wolters Kluwer Health in JBJS Open Access
- Vol. 7  (4)
The Impact of a Virtual Orthopaedic Surgery Symposium on Medical Students: Increasing Awareness and Knowledge of the Field
Background: Orthopaedic surgery has become an increasingly popular field of residency training for medical students. Many institutions offer elective time to explore areas of interest through clinical rotations and research; however, most of these opportunities are reserved for senior medical students. The purpose of this study was to evaluate the impact of a dedicated medical student orthopaedic surgery symposium to increase awareness about the field and to assess students' interest and knowledge of orthopaedic surgery before and after the symposium. Methods: Medical students were invited to submit orthopaedic surgery–related research to a free, 1-day virtual symposium held in April 2022. Abstracts were reviewed and selected from 9 different orthopaedic surgery subspecialty categories. Survey assessments were sent to medical students to complete before and after the symposium. The surveys included questions related to participant demographics as well as interest and knowledge about the field of orthopaedic surgery. Statistical analyses were completed to compare the participants' responses before and after the symposium. Results: In total, 962 medical students registered for the 4-hour symposium. Of these, 58.5% completed the presymposium survey and 48.0% completed the postsymposium survey. 13.3% of the respondents reported being “very knowledgeable” about the various orthopaedic surgery subspecialties before the symposium, which increased to 18.4% after the symposium. 46.9% of the participants stated that they were “knowledgeable” about the daily life of an orthopaedic surgery resident before the symposium, which increased to 67.3% after the symposium. Similarly, the percentage of respondents who reported that they were “very knowledgeable” about the residency match process increased from 12.2% presymposium to 22.4% postsymposium. Conclusions: As interest in pursuing a career in orthopaedic surgery increases, medical students will continue to seek information, mentorship, and opportunities to present their research in preparation for residency applications. Our study demonstrated that a large-scale, national, virtual orthopaedic surgery symposium provided a platform to augment medical students' knowledge of the field, present their research, and interact with faculty members. Level of Evidence: Level V.
- 29 November 2022
- Published by Wolters Kluwer Health in JBJS Open Access
- Vol. 7  (4)
Open AccessThe Impact of a Virtual Orthopaedic Surgery Symposium on Medical Students: Increasing Awareness and Knowledge of the Field
Background: Orthopaedic surgery has become an increasingly popular field of residency training for medical students. Many institutions offer elective time to explore areas of interest through clinical rotations and research; however, most of these opportunities are reserved for senior medical students. The purpose of this study was to evaluate the impact of a dedicated medical student orthopaedic surgery symposium to increase awareness about the field and to assess students' interest and knowledge of orthopaedic surgery before and after the symposium. Methods: Medical students were invited to submit orthopaedic surgery–related research to a free, 1-day virtual symposium held in April 2022. Abstracts were reviewed and selected from 9 different orthopaedic surgery subspecialty categories. Survey assessments were sent to medical students to complete before and after the symposium. The surveys included questions related to participant demographics as well as interest and knowledge about the field of orthopaedic surgery. Statistical analyses were completed to compare the participants' responses before and after the symposium. Results: In total, 962 medical students registered for the 4-hour symposium. Of these, 58.5% completed the presymposium survey and 48.0% completed the postsymposium survey. 13.3% of the respondents reported being “very knowledgeable” about the various orthopaedic surgery subspecialties before the symposium, which increased to 18.4% after the symposium. 46.9% of the participants stated that they were “knowledgeable” about the daily life of an orthopaedic surgery resident before the symposium, which increased to 67.3% after the symposium. Similarly, the percentage of respondents who reported that they were “very knowledgeable” about the residency match process increased from 12.2% presymposium to 22.4% postsymposium. Conclusions: As interest in pursuing a career in orthopaedic surgery increases, medical students will continue to seek information, mentorship, and opportunities to present their research in preparation for residency applications. Our study demonstrated that a large-scale, national, virtual orthopaedic surgery symposium provided a platform to augment medical students' knowledge of the field, present their research, and interact with faculty members. Level of Evidence: Level V.
- Open Access
- 19 November 2022
- Published by Springer Nature in Cureus
- Vol. 14  (11) , e31681
The Impact of the COVID-19 Pandemic on Orthopaedic Knee Procedures: A National Multicentered Analysis
Introduction: The coronavirus disease 2019 (COVID-19) pandemic strained the United States healthcare system, and associated policies resulted in the postponement or cancellation of many elective surgeries. While most orthopaedic surgeons are aware of how the pandemic affected their patients’ care, broader national trends in the operative treatment of orthopaedic knee pathology are poorly characterized. Therefore, the purpose of this study was to identify trends in orthopaedic knee procedures during the COVID-19 pandemic. Methods: The TriNetX database was queried for orthopaedic knee procedures performed from March 2018 to May 2021. Procedures were classified as arthroplasty (total knee arthroplasty (TKA), revision total knee arthroplasty) or non-arthroplasty (tendon or ligament repair, fracture fixation). Procedural volume per healthcare organization was determined over five seasons from March 2020 to May 2021 and compared to overlapping pre-pandemic periods from March 2018 to May 2019. Descriptive analysis was performed, and comparisons were made using a Student’s T-test. Results: Compared to the pre-pandemic period, there were significant decreases in primary TKA (p=0.016), femoral or entire tibial component revision TKA (p=0.005), and open treatment of femoral shaft fractures (p=0.007) in spring 2020. Procedural volume returned to baseline in summer 2020 through winter 2021. In spring 2021, primary TKA (p=0.017) and one component revision TKA (p=0.003) increased compared to the pre-pandemic period. Conclusion: The greatest decrease in knee procedures occurred early in the pandemic. Rates of these procedures have since rebounded, with some exceeding pre-pandemic levels. Hospitals are now better able to accommodate orthopaedic surgical volume while continuing to care for patients with COVID-19.
- 19 November 2022
- Published by Springer Nature in Cureus
- Vol. 14  (11) , e31681
Open AccessThe Impact of the COVID-19 Pandemic on Orthopaedic Knee Procedures: A National Multicentered Analysis
Introduction: The coronavirus disease 2019 (COVID-19) pandemic strained the United States healthcare system, and associated policies resulted in the postponement or cancellation of many elective surgeries. While most orthopaedic surgeons are aware of how the pandemic affected their patients’ care, broader national trends in the operative treatment of orthopaedic knee pathology are poorly characterized. Therefore, the purpose of this study was to identify trends in orthopaedic knee procedures during the COVID-19 pandemic. Methods: The TriNetX database was queried for orthopaedic knee procedures performed from March 2018 to May 2021. Procedures were classified as arthroplasty (total knee arthroplasty (TKA), revision total knee arthroplasty) or non-arthroplasty (tendon or ligament repair, fracture fixation). Procedural volume per healthcare organization was determined over five seasons from March 2020 to May 2021 and compared to overlapping pre-pandemic periods from March 2018 to May 2019. Descriptive analysis was performed, and comparisons were made using a Student’s T-test. Results: Compared to the pre-pandemic period, there were significant decreases in primary TKA (p=0.016), femoral or entire tibial component revision TKA (p=0.005), and open treatment of femoral shaft fractures (p=0.007) in spring 2020. Procedural volume returned to baseline in summer 2020 through winter 2021. In spring 2021, primary TKA (p=0.017) and one component revision TKA (p=0.003) increased compared to the pre-pandemic period. Conclusion: The greatest decrease in knee procedures occurred early in the pandemic. Rates of these procedures have since rebounded, with some exceeding pre-pandemic levels. Hospitals are now better able to accommodate orthopaedic surgical volume while continuing to care for patients with COVID-19.
- Open Access
- 15 November 2022
- Published by SAGE Publications in Foot & Ankle Orthopaedics
- Vol. 7  (4)
Association of Bleeding Disorders and Risk of Complications Following Open Reduction and Internal Fixation of the Ankle
Category: Ankle; Other Introduction/Purpose: Open reduction and internal fixation (ORIF) of the ankle is a common procedure performed to correct ankle fractures in many different patient populations. Diabetes, peripheral vascular disease, and osteoporosis have been identified as risk factors for postoperative complications following surgery for ankle fractures. To date, there have not been any studies evaluating postoperative outcomes in patients with bleeding disorders undergoing operative treatment for ankle fractures. The aim of this study was to determine the postoperative complication rate following ORIF of the ankle in patients with a bleeding disorder versus those without a bleeding disorder. Methods: From 2006 to 2018, patients undergoing operative treatment for ankle fracture were identified in the National Surgical Quality Improvement Program database. Two patient cohorts were defined: patients with a bleeding disorder and patients without a bleeding disorder. Patients who underwent either inpatient or outpatient ORIF of the ankle were included in this study. In this analysis, demographics, medical comorbidities, and postoperative complications variables were assessed between the two cohorts. Bivariate and multivariate analyses were performed. Results: Of 10,306 patients undergoing operative treatment for ankle fracture, 9,909 patients (96.1%) had no bleeding disorder whereas 397 patients (3.9%) had a bleeding disorder. Following adjustment on multivariate analysis, compared to patients who did not have a bleeding disorder, those with a bleeding disorder had an increased risk of any postoperative complications (OR 1.479; p=0.024), requirement for postoperative blood transfusion (OR 2.863; p=0.001), and extended length of hospital stay greater than 5 days (OR 1.455; p=0.010) (Table 1). Conclusion: Patients with bleeding disorders are at an increased risk of postoperative complications following ORIF for ankle fractures. Our study found that patients with bleeding disorders had greater odds of postoperative complications following ORIF of the ankle. Determining patient risk factors and creating optimal preoperative and perioperative management plans in patients with bleeding disorders undergoing ORIF can be beneficial in reducing postoperative complications, improving patient outcomes, and reducing overall cost.
- 15 November 2022
- Published by SAGE Publications in Foot & Ankle Orthopaedics
- Vol. 7  (4)
Open AccessAssociation of Bleeding Disorders and Risk of Complications Following Open Reduction and Internal Fixation of the Ankle
Category: Ankle; Other Introduction/Purpose: Open reduction and internal fixation (ORIF) of the ankle is a common procedure performed to correct ankle fractures in many different patient populations. Diabetes, peripheral vascular disease, and osteoporosis have been identified as risk factors for postoperative complications following surgery for ankle fractures. To date, there have not been any studies evaluating postoperative outcomes in patients with bleeding disorders undergoing operative treatment for ankle fractures. The aim of this study was to determine the postoperative complication rate following ORIF of the ankle in patients with a bleeding disorder versus those without a bleeding disorder. Methods: From 2006 to 2018, patients undergoing operative treatment for ankle fracture were identified in the National Surgical Quality Improvement Program database. Two patient cohorts were defined: patients with a bleeding disorder and patients without a bleeding disorder. Patients who underwent either inpatient or outpatient ORIF of the ankle were included in this study. In this analysis, demographics, medical comorbidities, and postoperative complications variables were assessed between the two cohorts. Bivariate and multivariate analyses were performed. Results: Of 10,306 patients undergoing operative treatment for ankle fracture, 9,909 patients (96.1%) had no bleeding disorder whereas 397 patients (3.9%) had a bleeding disorder. Following adjustment on multivariate analysis, compared to patients who did not have a bleeding disorder, those with a bleeding disorder had an increased risk of any postoperative complications (OR 1.479; p=0.024), requirement for postoperative blood transfusion (OR 2.863; p=0.001), and extended length of hospital stay greater than 5 days (OR 1.455; p=0.010) (Table 1). Conclusion: Patients with bleeding disorders are at an increased risk of postoperative complications following ORIF for ankle fractures. Our study found that patients with bleeding disorders had greater odds of postoperative complications following ORIF of the ankle. Determining patient risk factors and creating optimal preoperative and perioperative management plans in patients with bleeding disorders undergoing ORIF can be beneficial in reducing postoperative complications, improving patient outcomes, and reducing overall cost.