Olivier Berdeaux
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Olivier Berdeaux has a total of 28 co-authors. Here are the top co-authors by number of shared publications:
- Niyazi Acar
Eye & Nutrition Research Group, Université Bourgogne Europe, CHU Bourgogne, Public Health Department, Institut Agro, CNRS, INRAE, UMR CSGA, Dijon, France
2 shared publications - Alain Marie Bron
Rothschild Foundation Hospital, Paris, France
1 shared publication - Anaïs Alves
CarMeN laboratory, UMR INSERM U1060/INRAE U1397, Université Claude Bernard Lyon 1, Université de Lyon, 69310 Pierre-Bénite, France
1 shared publication - Arthur Bassot
CarMeN Laboratory, INSERM U1060, INRAE U1397, Université Lyon 1, 69008 Lyon, France
1 shared publication - Baptiste Panthu
Université Claude Bernard Lyon1, CarMeN Laboratory, INSERM, INRAE, 69310 Pierre-Bénite, France
1 shared publication - Benoit Chassaing
Microbiome-Host Interactions, Institut Pasteur, Université Paris Cité, INSERM U1306, Paris, France
1 shared publication
Latest Publications
- Open Access
- 10 February 2023
- Published by Elsevier in Journal of Lipid Research
- Vol. 64 (3) , 100343
Comprehensive mass spectrometry lipidomics of human biofluids and ocular tissues
- 10 February 2023
- Published by Elsevier in Journal of Lipid Research
- Vol. 64 (3) , 100343
Open AccessComprehensive mass spectrometry lipidomics of human biofluids and ocular tissues
- Open Access
Dietary Inulin Supplementation Affects Specific Plasmalogen Species in the Brain
Plasmalogens (Pls) are glycerophospholipids that play critical roles in the brain. Evidence supports the role of diet and that of the gut microbiota in regulating brain lipids. We investigated the impact of dietary intake of inulin—a soluble fiber used as prebiotic—on the Pl content of the cortex in mice. No global modification in the Pl amounts was observed when evaluated by gas chromatographic analysis of dimethyl acetals (DMAs). However, the analysis of individual molecular species of Pls by liquid chromatography revealed a reduced abundance of major species of ethanolamine Pls (PlsEtn)―PE(P-18:0/22:6) and PE(P-34:1)―in the cortex of mice fed a diet supplemented with inulin. DMA and expression levels of genes (Far-1, Gnpat, Agps, Pla2g6 and Tmem86b) encoding key enzymes of Pl biosynthesis or degradation were not altered in the liver and in the cortex of mice exposed to inulin. In addition, the fatty acid profile and the amount of lyso forms derived from PlsEtn were not modified in the cortex by inulin consumption. To conclude, inulin affects the brain levels of major PlsEtn and further investigation is needed to determine the exact molecular mechanisms involved.
Open AccessDietary Inulin Supplementation Affects Specific Plasmalogen Species in the Brain
Plasmalogens (Pls) are glycerophospholipids that play critical roles in the brain. Evidence supports the role of diet and that of the gut microbiota in regulating brain lipids. We investigated the impact of dietary intake of inulin—a soluble fiber used as prebiotic—on the Pl content of the cortex in mice. No global modification in the Pl amounts was observed when evaluated by gas chromatographic analysis of dimethyl acetals (DMAs). However, the analysis of individual molecular species of Pls by liquid chromatography revealed a reduced abundance of major species of ethanolamine Pls (PlsEtn)―PE(P-18:0/22:6) and PE(P-34:1)―in the cortex of mice fed a diet supplemented with inulin. DMA and expression levels of genes (Far-1, Gnpat, Agps, Pla2g6 and Tmem86b) encoding key enzymes of Pl biosynthesis or degradation were not altered in the liver and in the cortex of mice exposed to inulin. In addition, the fatty acid profile and the amount of lyso forms derived from PlsEtn were not modified in the cortex by inulin consumption. To conclude, inulin affects the brain levels of major PlsEtn and further investigation is needed to determine the exact molecular mechanisms involved.