Xavier Deparis
Xavier Deparis has a total of 38 co-authors. Here are the top co-authors by number of shared publications:
- Emmanuelle Anthoine
CHU Nantes, PHU Publ Hlth Dept 11, Nantes, France
2 shared publications - Jean-Luc Venisse
Stimulab Co, Pulsio Sante, Paris, France
2 shared publications - Julie Caillon
Nantes Université, CHU Nantes, UIC Psychiatrie et Santé Mentale, Nantes, France
2 shared publications - Leïla Moret
Service de Santé Publique, Nantes University Hospital, Nantes, France
2 shared publications - Marc-Antoine Brochard
STIMULAB company, 40 rue de la Tour d'Auvergne 44000 Nantes, France
2 shared publications - Maxime Lebeaupin
CHU Nantes, PHU Publ Hlth Dept 11, Nantes, France
2 shared publications
Latest Publications
- Open Access
- 16 October 2026
- Published by Springer Nature in Archives of Public Health
- Vol. 84 (1) , 224
What a highly monitored chikungunya epidemic reveals about preparedness for Europe and beyond
The 2024–25 chikungunya epidemic in Reunion Island illustrates the challenge of translating early warning into timely public-health action during fas
- 16 October 2026
- Published by Springer Nature in Archives of Public Health
- Vol. 84 (1) , 224
Open AccessWhat a highly monitored chikungunya epidemic reveals about preparedness for Europe and beyond
The 2024–25 chikungunya epidemic in Reunion Island illustrates the challenge of translating early warning into timely public-health action during fas
- Open Access
- 6 November 2025
- Published by Ubiquity Press, Ltd. in Annals of Global Health
- Vol. 91 (1) , 77
Seven Months After Tropical Cyclone Chido in Mayotte: Early Lessons and Brain Health Challenges
Background: On December 14, 2024, the tropical cyclone Chido hit the French department of Mayotte, an archipelago in the western Indian Ocean. It was the most violent storm in at least 90 years, causing widespread devastation. Objectives: We address different aspects of the Chido disaster, including deaths, Mayotte’s vulnerabilities, and risk management, and review the hurricane’s health consequences, notably post-traumatic stress disorder (PTSD). Methods: Information was collected through informal interviews with inhabitants, physicians, and stakeholders. Public data were provided by the public health authorities and through online searches. Findings: Addressing pre-Chido vulnerabilities, risk perception, fatality assessment, community management, and post-Chido psychological consequence constitutes a major challenge for the Mayotte society. Conclusion: We recommend launching an exploratory health study and planning to provide medico-psychological support to victims and to favor scientific investigations.
- 6 November 2025
- Published by Ubiquity Press, Ltd. in Annals of Global Health
- Vol. 91 (1) , 77
Open AccessSeven Months After Tropical Cyclone Chido in Mayotte: Early Lessons and Brain Health Challenges
Background: On December 14, 2024, the tropical cyclone Chido hit the French department of Mayotte, an archipelago in the western Indian Ocean. It was the most violent storm in at least 90 years, causing widespread devastation. Objectives: We address different aspects of the Chido disaster, including deaths, Mayotte’s vulnerabilities, and risk management, and review the hurricane’s health consequences, notably post-traumatic stress disorder (PTSD). Methods: Information was collected through informal interviews with inhabitants, physicians, and stakeholders. Public data were provided by the public health authorities and through online searches. Findings: Addressing pre-Chido vulnerabilities, risk perception, fatality assessment, community management, and post-Chido psychological consequence constitutes a major challenge for the Mayotte society. Conclusion: We recommend launching an exploratory health study and planning to provide medico-psychological support to victims and to favor scientific investigations.
- Open Access
- 1 October 2021
- Published by JMIR Publications Inc. in JMIR Formative Research
- Vol. 5 (10) , e15519
Assessing the Acceptability and Feasibility of a Web-Based Screening for Psychoactive Substance Users Among a French Sample of University Students and Workers: Mixed Methods Prospective Study
Journal of Medical Internet Research - International Scientific Journal for Medical Research, Information and Communication on the Internet #Preprint #PeerReviewMe: Warning: This is a unreviewed preprint. Readers are warned that the document has not been peer-reviewed by expert/patient reviewers or an academic editor, may contain misleading claims, and is likely to undergo changes before final publication, if accepted, or may have been rejected/withdrawn. Readers with interest and expertise are encouraged to sign up as peer-reviewer, if the paper is within an open peer-review period. Please cite this preprint only for review purposes or for grant applications and CVs (if you are the author). Background: Early detection in the prevention of addictive behaviours remains a complex question in practice for most first-line health professionals, despite its importance in terms of public health. Several prevention measures have successfully included a screening stage followed by a brief intervention in case of risk-related use or referral to an addiction centre for problematic use. Even though early detection is highly recommended by the WHO, it is not performed in practice. Objective: To assess acceptability and feasibility of a web-based application, “Pulsio Santé”, for health service users and first-line prevention professionals. Methods: A mixed-method prospective pilot study was conducted in 2017 in two departments: The Nantes occupational health department responsible for monitoring the health of salaried personnel across the region, and the university department of preventive medicine with a health unit dedicated to university students. In each department, all health professionals (physicians and nurses) were invited to participate in the study. Subjects 18 or older seen by a health professional from one of the departments were eligible. The study procedure comprised 4 phases: 1) inclusion of participants by health professionals face-to-face, 2) self-automated web-based assessment report filled in by participants on their substance use with “Pulsio Santé” based on ASSIST questionnaire. Participants received a text message on their smartphone or by email, 3) if participants agreed, they could transfer results to their health professional. If not, messages appeared allowing them to get in touch with their general practitioner, should the assessment detect a risk. Two levels of feasibility and acceptability criteria were assessed. Two focus group sessions with health professionals were performed, exploring their points of view on the acceptability and feasibility of the web-based application. A multi-category content analysis was done. Results: 1474 people were eligible and 44 health professionals participated in the study. The first level of acceptability (% of people who agreed to receive a text message or an email) was 79.2% (1167 out of 1474). The second level of acceptability (% of participants who click on the self-assessment link) was 60.2% (703 out of 1167). The first level of feasibility (% of participants who completed their self-evaluation entirely) was 76.2% (536 out of 703). The second level of feasibility (% of participants who shared the results with their health professional) was 79.5% (426 out of 536). Health professionals highlighted obstacles to carry out the recommended interventions for people at risk based on their online screening. Conclusions: Our pilot study on a large sample showed good acceptability and feasibility of “Pulsio Santé” by health service users and professionals. The need for further studies more directly focused on the limitations emerged.
- 1 October 2021
- Published by JMIR Publications Inc. in JMIR Formative Research
- Vol. 5 (10) , e15519
Open AccessAssessing the Acceptability and Feasibility of a Web-Based Screening for Psychoactive Substance Users Among a French Sample of University Students and Workers: Mixed Methods Prospective Study
Journal of Medical Internet Research - International Scientific Journal for Medical Research, Information and Communication on the Internet #Preprint #PeerReviewMe: Warning: This is a unreviewed preprint. Readers are warned that the document has not been peer-reviewed by expert/patient reviewers or an academic editor, may contain misleading claims, and is likely to undergo changes before final publication, if accepted, or may have been rejected/withdrawn. Readers with interest and expertise are encouraged to sign up as peer-reviewer, if the paper is within an open peer-review period. Please cite this preprint only for review purposes or for grant applications and CVs (if you are the author). Background: Early detection in the prevention of addictive behaviours remains a complex question in practice for most first-line health professionals, despite its importance in terms of public health. Several prevention measures have successfully included a screening stage followed by a brief intervention in case of risk-related use or referral to an addiction centre for problematic use. Even though early detection is highly recommended by the WHO, it is not performed in practice. Objective: To assess acceptability and feasibility of a web-based application, “Pulsio Santé”, for health service users and first-line prevention professionals. Methods: A mixed-method prospective pilot study was conducted in 2017 in two departments: The Nantes occupational health department responsible for monitoring the health of salaried personnel across the region, and the university department of preventive medicine with a health unit dedicated to university students. In each department, all health professionals (physicians and nurses) were invited to participate in the study. Subjects 18 or older seen by a health professional from one of the departments were eligible. The study procedure comprised 4 phases: 1) inclusion of participants by health professionals face-to-face, 2) self-automated web-based assessment report filled in by participants on their substance use with “Pulsio Santé” based on ASSIST questionnaire. Participants received a text message on their smartphone or by email, 3) if participants agreed, they could transfer results to their health professional. If not, messages appeared allowing them to get in touch with their general practitioner, should the assessment detect a risk. Two levels of feasibility and acceptability criteria were assessed. Two focus group sessions with health professionals were performed, exploring their points of view on the acceptability and feasibility of the web-based application. A multi-category content analysis was done. Results: 1474 people were eligible and 44 health professionals participated in the study. The first level of acceptability (% of people who agreed to receive a text message or an email) was 79.2% (1167 out of 1474). The second level of acceptability (% of participants who click on the self-assessment link) was 60.2% (703 out of 1167). The first level of feasibility (% of participants who completed their self-evaluation entirely) was 76.2% (536 out of 703). The second level of feasibility (% of participants who shared the results with their health professional) was 79.5% (426 out of 536). Health professionals highlighted obstacles to carry out the recommended interventions for people at risk based on their online screening. Conclusions: Our pilot study on a large sample showed good acceptability and feasibility of “Pulsio Santé” by health service users and professionals. The need for further studies more directly focused on the limitations emerged.
- Open Access
- 16 July 2019
- Published by JMIR Publications Inc. in JMIR Preprints
Assessing the Acceptability and Feasibility of a Web-Based Screening for Psychoactive Substance Users Among a French Sample of University Students and Workers: Mixed Methods Prospective Study (Preprint)
BACKGROUND Early detection in the prevention of addictive behaviors remains a complex question in practice for most first-line health care workers (HCWs). Several prevention measures have successfully included a screening stage followed by a brief intervention in case of risk-related use or referral to an addiction center for problematic use. Whereas early detection is highly recommended by the World Health Organization, it is not usually performed in practice. OBJECTIVE The aim of this study was to assess the acceptability and feasibility of a web-based app, called Pulsio Santé, for health service users and first-line prevention HCW and to carry out an exhaustive process of early detection of psychoactive substance use behaviors. METHODS A mixed methods prospective study was conducted in 2 departments: HCWs from the regional occupational health department and from the university department of preventive medicine dedicated to students were invited to participate. Participants 18 years or older who had been seen in 2017 by a HCW from one of the departments were eligible. The study procedure comprised 5 phases: (1) inclusion of the participants after a face-to-face consultation with an HCW; (2) reception of a text message by participants on their smartphone or by email; (3) self-assessment by participants regarding their substance use with the Pulsio Santé app; (4) if participants agreed, transfer of the results to the HCW; and (5) if participants declined, a message to invite them to get in touch with their general practitioner should the assessment detect a risk. Several feasibility and acceptability criteria were assessed by an analysis of a focus group with the HCW that explored 4 themes (usefulness and advantages, problems and limitations, possible improvements, and finally, integration into routine practice). RESULTS A total of 1474 people were asked to participate, with 42 HCWs being involved. The percentage of people who agreed to receive a text message or an email, which was considered as the first level of acceptability, was 79.17% (1167/1474). The percentage of participants who clicked on the self-assessment link, considered as the second level of acceptability, was 60.24% (703/1167). The percentage of participants who completed their self-evaluation entirely, which was considered as the first level of feasibility, was 76.24% (536/703). The percentage of participants who shared the results of their evaluation with the HCWs, considered as the second level of feasibility, was 79.48% (426/536). The qualitative study showed that there were obstacles on the side of HCWs in carrying out the recommended interventions for people at risk based on their online screening, such as previous training or adaptations in accordance with specific populations. CONCLUSIONS Quantitative results showed good acceptability and feasibility of the Pulsio Santé app by users and HCWs. There is a need for further studies more directly focused on the limitations highlighted by the qualitative results.
- 16 July 2019
- Published by JMIR Publications Inc. in JMIR Preprints
Open AccessAssessing the Acceptability and Feasibility of a Web-Based Screening for Psychoactive Substance Users Among a French Sample of University Students and Workers: Mixed Methods Prospective Study (Preprint)
BACKGROUND Early detection in the prevention of addictive behaviors remains a complex question in practice for most first-line health care workers (HCWs). Several prevention measures have successfully included a screening stage followed by a brief intervention in case of risk-related use or referral to an addiction center for problematic use. Whereas early detection is highly recommended by the World Health Organization, it is not usually performed in practice. OBJECTIVE The aim of this study was to assess the acceptability and feasibility of a web-based app, called Pulsio Santé, for health service users and first-line prevention HCW and to carry out an exhaustive process of early detection of psychoactive substance use behaviors. METHODS A mixed methods prospective study was conducted in 2 departments: HCWs from the regional occupational health department and from the university department of preventive medicine dedicated to students were invited to participate. Participants 18 years or older who had been seen in 2017 by a HCW from one of the departments were eligible. The study procedure comprised 5 phases: (1) inclusion of the participants after a face-to-face consultation with an HCW; (2) reception of a text message by participants on their smartphone or by email; (3) self-assessment by participants regarding their substance use with the Pulsio Santé app; (4) if participants agreed, transfer of the results to the HCW; and (5) if participants declined, a message to invite them to get in touch with their general practitioner should the assessment detect a risk. Several feasibility and acceptability criteria were assessed by an analysis of a focus group with the HCW that explored 4 themes (usefulness and advantages, problems and limitations, possible improvements, and finally, integration into routine practice). RESULTS A total of 1474 people were asked to participate, with 42 HCWs being involved. The percentage of people who agreed to receive a text message or an email, which was considered as the first level of acceptability, was 79.17% (1167/1474). The percentage of participants who clicked on the self-assessment link, considered as the second level of acceptability, was 60.24% (703/1167). The percentage of participants who completed their self-evaluation entirely, which was considered as the first level of feasibility, was 76.24% (536/703). The percentage of participants who shared the results of their evaluation with the HCWs, considered as the second level of feasibility, was 79.48% (426/536). The qualitative study showed that there were obstacles on the side of HCWs in carrying out the recommended interventions for people at risk based on their online screening, such as previous training or adaptations in accordance with specific populations. CONCLUSIONS Quantitative results showed good acceptability and feasibility of the Pulsio Santé app by users and HCWs. There is a need for further studies more directly focused on the limitations highlighted by the qualitative results.
- Open Access
- 1 November 2016
- Published by Elsevier in New Microbes and New Infections
- Vol. 14, 6-7
Compared lethality rates of Clostridium difficile infections at the local, regional and national levels in France
- 1 November 2016
- Published by Elsevier in New Microbes and New Infections
- Vol. 14, 6-7
Open AccessCompared lethality rates of Clostridium difficile infections at the local, regional and national levels in France
- Open Access
- 17 March 2016
- Published by Springer Nature in Malaria Journal
- Vol. 15 (1) , 174
Factors associated with malaria chemoprophylaxis compliance among French service members deployed in Central African Republic
Malaria is a public health concern in the French armed forces, with 400–800 cases reported every year and three deaths in the past 2 years. However, lack of chemoprophylaxis (CP) compliance is often reported among service members. The aim of this study was to explore factors associated with CP compliance. A retrospective study (1296 service members) was carried out among troops deployed in Central African Republic. Determinants of CP were collected by self-questionnaire. Socio-demographic variables, behavioural characteristics, belief variables, operational determinants such as troops in contact (TIC) and number of nights worked per week and peer-to-peer reinforcement were studied. Relationships between covariates and compliance were explored using logistic regressions (outcome: compliance as a dummy variable). Chemoprophylaxis compliance was associated with other individual preventive measures against mosquito bites (bed net use, OR (odds ratio) = 1.41 (95 % CI [1.08–1.84]), and insecticide on clothing, OR = 1.90 ([1.43–2.51]) and malaria-related behaviours (taking chemoprophylaxis at the same time every day, OR = 2.37 ([1.17–4.78]) and taking chemoprophylaxis with food, OR = 1.45 ([1.11–1.89])). High perceived risk of contracting malaria, OR = 1.59 ([1.02–2.50]), positive perception of CP effectiveness, OR = 1.62 ([1.09–2.40]) and the practice of peer-to-peer reinforcement, OR = 1.38 ([1.05–1.82]) were also associated with better compliance. No association was found with TIC and number of nights worked. This study, which shows a positive relationship between peer-to-peer reinforcement and CP compliance, also suggests the existence of two main personality profiles among service members: those who seek risks and those who are health-conscious. Health education should be expanded beyond knowledge, know-how and motivational factors by using a comprehensive approach based on identification of health determinants, development of psychosocial skills and peer-to-peer reinforcement.
- 17 March 2016
- Published by Springer Nature in Malaria Journal
- Vol. 15 (1) , 174
Open AccessFactors associated with malaria chemoprophylaxis compliance among French service members deployed in Central African Republic
Malaria is a public health concern in the French armed forces, with 400–800 cases reported every year and three deaths in the past 2 years. However, lack of chemoprophylaxis (CP) compliance is often reported among service members. The aim of this study was to explore factors associated with CP compliance. A retrospective study (1296 service members) was carried out among troops deployed in Central African Republic. Determinants of CP were collected by self-questionnaire. Socio-demographic variables, behavioural characteristics, belief variables, operational determinants such as troops in contact (TIC) and number of nights worked per week and peer-to-peer reinforcement were studied. Relationships between covariates and compliance were explored using logistic regressions (outcome: compliance as a dummy variable). Chemoprophylaxis compliance was associated with other individual preventive measures against mosquito bites (bed net use, OR (odds ratio) = 1.41 (95 % CI [1.08–1.84]), and insecticide on clothing, OR = 1.90 ([1.43–2.51]) and malaria-related behaviours (taking chemoprophylaxis at the same time every day, OR = 2.37 ([1.17–4.78]) and taking chemoprophylaxis with food, OR = 1.45 ([1.11–1.89])). High perceived risk of contracting malaria, OR = 1.59 ([1.02–2.50]), positive perception of CP effectiveness, OR = 1.62 ([1.09–2.40]) and the practice of peer-to-peer reinforcement, OR = 1.38 ([1.05–1.82]) were also associated with better compliance. No association was found with TIC and number of nights worked. This study, which shows a positive relationship between peer-to-peer reinforcement and CP compliance, also suggests the existence of two main personality profiles among service members: those who seek risks and those who are health-conscious. Health education should be expanded beyond knowledge, know-how and motivational factors by using a comprehensive approach based on identification of health determinants, development of psychosocial skills and peer-to-peer reinforcement.
- 1 February 2008
- Published by Elsevier in Revue D'Épidémiologie Et de Santé Publique
- Vol. 56 (1) , 11-20
Surveillance épidémiologique en temps réel dans les armées ; concepts, réalités et perspectives en France
- 1 February 2008
- Published by Elsevier in Revue D'Épidémiologie Et de Santé Publique
- Vol. 56 (1) , 11-20
Surveillance épidémiologique en temps réel dans les armées ; concepts, réalités et perspectives en France