Eya Moussaoui

PurposeThe aim of this study was to evaluate the concordance between the histopathological diagnoses obtained from biopsies of maxillofacial lesions and the definitive histopathological diagnoses of the excised specimens, and to identify factors associated with diagnostic discordance.Subjects and methodsA retrospective cross-sectional study was conducted on 203 patients with maxillofacial lesions who underwent surgical excision following biopsy between 2005 and 2019. Sociodemographic, clinical, and histopathological data were collected and analyzed. Biopsy diagnoses were compared with the final excision diagnoses using Cohen’s kappa coefficient and appropriate statistical tests.ResultsThe histopathological diagnosis of the excised specimen was consistent with the biopsy diagnosis in 87.8% of cases (p = 0.001). No significant differences were found between biopsy and excision diagnoses when the biopsy was performed by a specialist or a resident (p = 0.29), or when the histopathological evaluation was conducted by a resident or a specialist pathologist (p = 0.59). Likewise, no significant differences were observed according to whether the biopsy specimen consisted of a single fragment or multiple fragments (p = 0.65).ConclusionCareful identification and management of factors contributing to diagnostic discordance may improve the reliability of biopsy diagnoses and consequently enhance patient management.

Alveolar osteitis is a common complication occurs after tooth extraction, this complication can affected healthy people although it is cause is unknown. Therefore, alveolar osteitis management has always based on empirical treatment rather than scientific knowledge. The present study detect the efficacy of low levellaser therapy (LLLT) the healing of alveolar osteitis. Materials and methods: Patients who diagnosed with alveolar osteitis at the Al Ameeed dental clinic in AL Ameed University / College of Dentistry were enrolled in a randomized controlled clinical trial. Sixty patients has been divided equally into two groups for received different treatments: the first group received traditional therapy which include socket curettage and irrigation with saline, while the second group received low-level laser therapy. All the dry sockets were assessments on day 0 before intervention and then on day 4th and 7th of follow up. the pain, depth, piresocket inflammation and perisocket tenderness of dry socket were evaluated in each visit. Results: Two therapy groups were established using 60 dry socket patients. The median of pain score, granulation tissue formation, tenderness, inflammation of the socket show there are significant improvement of group II LLLT compared to the conventional treatment. Conclusion: The low-level laser therapy has a superior effect on the reduction period of the healing process of alveolar osteitis. On the other hand the conventional therapy may improve the sign and symptoms of the alveolar osteitis but don’t reduce the time of healing process.

A dry socket is a commonly seen issue that happens throughout the process of wound healing following a tooth extraction. The etiology of this condition is still limited understood, and it frequently manifests in persons who have a state of good health. As a consequence, the management strategies for dry sockets have always depended on practical experience rather than scientific theory. This study aims to assess the efficacy of platelets-rich fibrin (PRF) in treating dry sockets and compare it with traditional therapy methods. A randomized controlled clinical trial was conducted among patients with a dry socket, who were categorized into two treatment groups. In the group I, the conventional treatment was used with performing gentle socket curettage and saline irrigation. The group II was treated with platelet-rich fibrin (PRF); the dry socket patients were examined at day 0 and achieved one of two treatment options, then scheduled follow-up appointments on days 4 and 7 after therapy. The pain score, inflammation and tenderness around the socket, and quantity of granulation tissue formation were assessed, respectively. In total, sixty patients with a dry socket were included in two treatment groups. The results show that The conventional therapy group required more than seven days to reach the same healing phase as group II with PRF-treated socket. It was observed that the PRF-treated group II patients experienced an improvement in pain, tenderness, inflammation and granulation tissue formation. The sockets treated with PRF showed statistically significant improvement in the healing process and granulation tissue formation compared with conventional treatment.

A dry socket is a commonly seen issue that happens throughout the process of wound healing following a tooth extraction. The etiology of this condition is still limited understood, and it frequently manifests in persons who have a state of good health. As a consequence, the management strategies for dry sockets have always depended on practical experience rather than scientific theory. This study aims to assess the efficacy of platelets-rich fibrin (PRF) in treating dry sockets and compare it with traditional therapy methods. A randomized controlled clinical trial was conducted among patients with a dry socket, who were categorized into two treatment groups. In the group I, the conventional treatment was used with performing gentle socket curettage and saline irrigation. The group II was treated with platelet-rich fibrin (PRF); the dry socket patients were examined at day 0 and achieved one of two treatment options, then scheduled follow-up appointments on days 4 and 7 after therapy. The pain score, inflammation and tenderness around the socket, and quantity of granulation tissue formation were assessed, respectively. In total, sixty patients with a dry socket were included in two treatment groups. The results show that The conventional therapy group required more than seven days to reach the same healing phase as group II with PRF-treated socket. It was observed that the PRF-treated group II patients experienced an improvement in pain, tenderness, inflammation and granulation tissue formation. The sockets treated with PRF showed statistically significant improvement in the healing process and granulation tissue formation compared with conventional treatment.

Ossification of stylohyoid chain corresponds to the ossification of stylohyoid ligament that can vary from thin short to thick long ossification and can be associated with other calcifications. We report in this case a bilateral non painful complete ossification of the stylohyoid complex extended to the thyrohyoidien ligament.

Uremic stomatitis is a rare manifestation associated with longstanding uremia in chronic renal failure patients. Its evolution is favorable with earlier institution of renal replacement therapy. We report a case of hyperkeratotic uremic stomatitis that revealed decompensation of chronic kidney disease.

Ossification of stylohyoid chain corresponds to the ossification of stylohyoid ligament that can vary from thin short to thick long ossification and can be associated with other calcifications. We report in this case a bilateral non painful complete ossification of the stylohyoid complex extended to the thyrohyoidien ligament.

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a distinct part of severe cutaneous adverse reactions (SCARs). It is characterized by fever, rash, hematologic abnormalities, lymphadenopathy, or/and different degrees of visceral organ involvement. Its diagnosis is particularly challenging due to the variability of its clinical presentations and its long latency period (2–6 weeks). Allopurinol, an uric acid‐lowering drug, has been incriminated in several cases of allopurinol‐induced DRESS syndrome. Through this paper, we present a case of allopurinol‐induced DRESS syndrome with initial oral mucosal involvement. A 69‐year‐old female patient presented with an erosive cheilitis that started 1 week prior to his presentation. The cheilitis was associated with maculopapular rash and fever. She started taking allopurinol, as treatment of Gout, 6 weeks before hospitalization. The histologic findings obtained from skin biopsy were consistent with a toxic drug reaction. A complete blood count (CBC) showed a moderate eosinophilia. Alteration of renal function was also noted, and the diagnosis of allopurinol‐induced DRESS syndrome was made. Systemic corticosteroid therapy was therefore started. The patient completely recovered and had been healthy for 3 years before developing a recurrence after re‐challenge with allopurinol.

Uremic stomatitis is a rare manifestation associated with longstanding uremia in chronic renal failure patients. Its evolution is favorable with earlier institution of renal replacement therapy. This case shows that this condition should always be suspected by the dentist when the context of advanced renal disease is present.

Drug reaction with eosinophilia and systemic symptoms (DRESS) is part of Severe cutaneous adverse reactions. Allopurinol, an uric acid-lowering drug, had been incriminated in several cases of Allopurinol-induced Dress syndrome.Through this paper, we present a case of Allopurinol-induced DRESS syndrome with initial oral mucosal involvement.