Justin Rhee
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Justin Rhee has a total of 31 co-authors. Here are the top co-authors by number of shared publications:
- Adam J. Kucharski
Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
1 shared publication - Alex Lee Zhu
Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA
1 shared publication - Anil S. Menon
University of Texas Medical Branch, Galveston, USA
1 shared publication - Benjamin Mormann
Brigham and Women’s Hospital, Boston, MA 02115, USA
1 shared publication - Boris Julg
Infectious Diseases Division, Massachusetts General Hospital, Harvard Medical School, 600 Main street, 02139, Cambridge, MA, USA.
1 shared publication - Caroline Atyeo
Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA
1 shared publication
Latest Publications
- Open Access
Epidemiological and Immunological Features of Obesity and SARS-CoV-2
Obesity is a key correlate of severe SARS-CoV-2 outcomes while the role of obesity on risk of SARS-CoV-2 infection, symptom phenotype, and immune response remain poorly defined. We examined data from a prospective SARS-CoV-2 cohort study to address these questions. Serostatus, body mass index, demographics, comorbidities, and prior COVID-19 compatible symptoms were assessed at baseline and serostatus and symptoms monthly thereafter. SARS-CoV-2 immunoassays included an IgG ELISA targeting the spike RBD, multiarray Luminex targeting 20 viral antigens, pseudovirus neutralization, and T cell ELISPOT assays. Our results from a large prospective SARS-CoV-2 cohort study indicate symptom phenotype is strongly influenced by obesity among younger but not older age groups; we did not identify evidence to suggest obese individuals are at higher risk of SARS-CoV-2 infection; and remarkably homogenous immune activity across BMI categories suggests immune protection across these groups may be similar.
Open AccessEpidemiological and Immunological Features of Obesity and SARS-CoV-2
Obesity is a key correlate of severe SARS-CoV-2 outcomes while the role of obesity on risk of SARS-CoV-2 infection, symptom phenotype, and immune response remain poorly defined. We examined data from a prospective SARS-CoV-2 cohort study to address these questions. Serostatus, body mass index, demographics, comorbidities, and prior COVID-19 compatible symptoms were assessed at baseline and serostatus and symptoms monthly thereafter. SARS-CoV-2 immunoassays included an IgG ELISA targeting the spike RBD, multiarray Luminex targeting 20 viral antigens, pseudovirus neutralization, and T cell ELISPOT assays. Our results from a large prospective SARS-CoV-2 cohort study indicate symptom phenotype is strongly influenced by obesity among younger but not older age groups; we did not identify evidence to suggest obese individuals are at higher risk of SARS-CoV-2 infection; and remarkably homogenous immune activity across BMI categories suggests immune protection across these groups may be similar.