Angela Catapano
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Angela Catapano has a total of 15 co-authors. Here are the top co-authors by number of shared publications:
- Daniela Sorriento
Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy; Interdepartmental Center of Research on Hypertension and Related Conditions (CIRIAPA), Federico II University, Naples, Italy
1 shared publication - Elisabetta Murru
Department of Biomedical Sciences, University of Cagliari, 09042 Monserrato, CA, Italy
1 shared publication - Fabiano Cimmino
Department of Biology, University of Naples Federico II, 80126 Naples, Italy
1 shared publication - Gina Cavaliere
Department of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, Italy
1 shared publication - Giovanna Trinchese
Department of Biology, University of Naples Federico II, 80126 Naples, Italy
1 shared publication - Guido Iaccarino
Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy
1 shared publication
Latest Publications
- Open Access
- 13 November 2021
- Published by MDPI AG in Antioxidants
- Vol. 10 (11) , 1807
Heart Mitochondrial Metabolic Flexibility and Redox Status Are Improved by Donkey and Human Milk Intake
The biological mechanisms linking nutrition and antioxidants content of the diet with cardiovascular protection are subject of intense investigation. It has been demonstrated that dietary supplementation with cow, donkey or human milk, characterized by distinct nutritional properties, triggers significant differences in the metabolic and inflammatory status through the modulation of hepatic and skeletal muscle mitochondrial functions. Cardiac mitochondria play a key role for energy-demanding heart functions, and their disfunctions is leading to pathologies. Indeed, an altered heart mitochondrial function and the consequent increased reactive oxygen species (ROS) production and inflammatory state, is linked to several cardiac diseases such as hypertension and heart failure. In this work it was investigated the impact of the milk consumption on heart mitochondrial functions, inflammation and oxidative stress. In addition, it was underlined the crosstalk between mitochondrial metabolic flexibility, lipid storage and redox status as control mechanisms for the maintenance of cardiovascular health.
- 13 November 2021
- Published by MDPI AG in Antioxidants
- Vol. 10 (11) , 1807
Open AccessHeart Mitochondrial Metabolic Flexibility and Redox Status Are Improved by Donkey and Human Milk Intake
The biological mechanisms linking nutrition and antioxidants content of the diet with cardiovascular protection are subject of intense investigation. It has been demonstrated that dietary supplementation with cow, donkey or human milk, characterized by distinct nutritional properties, triggers significant differences in the metabolic and inflammatory status through the modulation of hepatic and skeletal muscle mitochondrial functions. Cardiac mitochondria play a key role for energy-demanding heart functions, and their disfunctions is leading to pathologies. Indeed, an altered heart mitochondrial function and the consequent increased reactive oxygen species (ROS) production and inflammatory state, is linked to several cardiac diseases such as hypertension and heart failure. In this work it was investigated the impact of the milk consumption on heart mitochondrial functions, inflammation and oxidative stress. In addition, it was underlined the crosstalk between mitochondrial metabolic flexibility, lipid storage and redox status as control mechanisms for the maintenance of cardiovascular health.