Amit Saxena

Alzheimer’s disease is a chronic neurodegenerative disease that causes brain cells to degenerate, resulting in decreased physical and mental abilities and, in severe cases, permanent memory loss. It is considered as the most common and fatal form of dementia. Although mild cognitive impairment (MCI) precedes Alzheimer’s disease (AD), it does not necessarily show the obvious symptoms of AD. As a result, it becomes challenging to distinguish between mild cognitive impairment and cognitively normal. In this paper, we propose an ensemble of deep learners based on convolutional neural networks for the early diagnosis of Alzheimer’s disease. The proposed approach utilises simple averaging ensemble and weighted averaging ensemble methods. The ensemble-based transfer learning model demonstrates enhanced generalization and performance for AD diagnosis compared to traditional transfer learning methods. Extensive experiments on the OASIS-3 dataset validate the effectiveness of the proposed model, showcasing its superiority over state-of-the-art transfer learning approaches in terms of accuracy, robustness, and efficiency.

In remote sensing imagery, segmentation techniques fail to encounter multiple regions of interest due to challenges such as dense features, low illumination, uncertainties, and noise. Consequently, exploiting vast and redundant information makes segmentation a difficult task. Existing multilevel thresholding techniques achieve low segmentation accuracy with high temporal difficulty due to the absence of spatial information. To mitigate this issue, this paper presents a new Rényi’s entropy and modified cuckoo search-based robust automatic multi-thresholding algorithm for remote sensing image analysis. In the proposed method, the modified cuckoo search algorithm is combined with Rényi’s entropy thresholding criteria to determine optimal thresholds. In the modified cuckoo search algorithm, the Lévy flight step size was modified to improve the convergence rate. An experimental analysis was conducted to validate the proposed method, both qualitatively and quantitatively against existing metaheuristic-based thresholding methods. To do this, the performance of the proposed method was intensively examined on high-dimensional remote sensing imageries. Moreover, numerical parameter analysis is presented to compare the segmented results against the gray-level co-occurrence matrix, Otsu energy curve, minimum cross entropy, and Rényi’s entropy-based thresholding. Experiments demonstrated that the proposed approach is effective and successful in attaining accurate segmentation with low time complexity.