Philippe Reymond
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Philippe Reymond has a total of 6 co-authors. Here are the top co-authors by number of shared publications:
- Christoph Huber
Department of Cardiovascular Surgery, Geneva University Hospital, Geneva, Switzerland
1 shared publication - Gérald Richard
Charles Hahn Hemodynamic Propulsion Laboratory, Medical Faculty, University of Geneva, 1211 Geneva, Switzerland
1 shared publication - Karim Bendjelid
Intensive Care Division, Department of Acute Medicine, Geneva University Hospitals, Geneva, Switzerland
1 shared publication - Mustafa Cikirikcioglu
Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland
1 shared publication - Nicolas Murith
Cardiovascular Surgery Division, Department of Surgery, Geneva University Hospitals (Hôpitaux Universitaires de Genève, HUG), 1205 Geneva, Switzerland, Switzerland
1 shared publication - Raphaël Giraud
Intensive Care Division, Department of Acute Care Medicine, Geneva University Hospitals
1 shared publication
Latest Publications
- Open Access
- 16 November 2021
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 10 (22) , 5333
To Balloon or Not to Balloon? The Effects of an Intra-Aortic Balloon-Pump on Coronary Artery Flow during Extracorporeal Circulation Simulating Normal and Low Cardiac Output Syndromes
ECMO is the most frequently used mechanical support for patients suffering from low cardiac output syndrome. Combining IABP with ECMO is believed to increase coronary artery blood flow, decrease high afterload, and restore systemic pulsatile flow conditions. This study evaluates that combined effect on coronary artery flow during various load conditions using an in vitro circuit. In doing so, different clinical scenarios were simulated, such as normal cardiac output and moderate-to-severe heart failure. In the heart failure scenarios, we used peripheral ECMO support to compensate for the lowered cardiac output value and reach a default normal value. The increase in coronary blood flow using the combined IABP-ECMO setup was more noticeable in low heart rate conditions. At baseline, intermediate and severe LV failure levels, adding IABP increased coronary mean flow by 16%, 7.5%, and 3.4% (HR 60 bpm) and by 6%, 4.5%, and 2.5% (HR 100 bpm) respectively. Based on our in vitro study results, combining ECMO and IABP in a heart failure setup further improves coronary blood flow. This effect was more pronounced at a lower heart rate and decreased with heart failure, which might positively impact recovery from cardiac failure.
- 16 November 2021
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 10 (22) , 5333
Open AccessTo Balloon or Not to Balloon? The Effects of an Intra-Aortic Balloon-Pump on Coronary Artery Flow during Extracorporeal Circulation Simulating Normal and Low Cardiac Output Syndromes
ECMO is the most frequently used mechanical support for patients suffering from low cardiac output syndrome. Combining IABP with ECMO is believed to increase coronary artery blood flow, decrease high afterload, and restore systemic pulsatile flow conditions. This study evaluates that combined effect on coronary artery flow during various load conditions using an in vitro circuit. In doing so, different clinical scenarios were simulated, such as normal cardiac output and moderate-to-severe heart failure. In the heart failure scenarios, we used peripheral ECMO support to compensate for the lowered cardiac output value and reach a default normal value. The increase in coronary blood flow using the combined IABP-ECMO setup was more noticeable in low heart rate conditions. At baseline, intermediate and severe LV failure levels, adding IABP increased coronary mean flow by 16%, 7.5%, and 3.4% (HR 60 bpm) and by 6%, 4.5%, and 2.5% (HR 100 bpm) respectively. Based on our in vitro study results, combining ECMO and IABP in a heart failure setup further improves coronary blood flow. This effect was more pronounced at a lower heart rate and decreased with heart failure, which might positively impact recovery from cardiac failure.