Geonho Cho
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Geonho Cho has a total of 6 co-authors. Here are the top co-authors by number of shared publications:
- Sung Wng Kim
Department of Mechanical Engineering, Inha University, 100, Inha-Ro, Michuhol-Gu, Incheon 22212, Republic of Korea
3 shared publications - Tae-Joon Jeon
Department of Biological Sciences and Bioengineering, Inha University, Incheon 22212, Republic of Korea
3 shared publications - Chen
Department of Biological Sciences and Bioengineering, Inha University, 100, Inha-ro, Michuhol-gu, Incheon 22212, Korea
1 shared publication - Deborah Lee
Department of Biological Engineering, Inha University, 100, Inha-ro, Michuhol-gu, Incheon 22212, Korea
1 shared publication - Kidong Kim
Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea
1 shared publication - Sejin Son
Department of Biological Sciences and Bioengineering, Inha University/Industry-Academia Interactive R&E Center for Bioprocess Innovation, Incheon, South Korea
1 shared publication
Latest Publications
- 22 June 2024
- Published by Elsevier in Chemical Engineering Journal
- Vol. 495, 153407
Nanopore detection of sub-nanosized plastics in PE-coated paper cups and analysis of their inflammatory responses
- 22 June 2024
- Published by Elsevier in Chemical Engineering Journal
- Vol. 495, 153407
Nanopore detection of sub-nanosized plastics in PE-coated paper cups and analysis of their inflammatory responses
- Open Access
- 30 June 2023
- Published by Korean Society for Biotechnology and Bioengineering in KSBB Journal
- Vol. 38 (2) , 90-99
Trends in 3D Printed Microfluidic Devices for Biotechnology Research
Geonho Cho, Sun Min Kim, and Tae-Joon Jeon. Korean Society for Biotechnology and Bioengineering Journal 2023;38:90-9. https://doi.org/10.7841/ksbbj.2023.38.2.90
- 30 June 2023
- Published by Korean Society for Biotechnology and Bioengineering in KSBB Journal
- Vol. 38 (2) , 90-99
Open AccessTrends in 3D Printed Microfluidic Devices for Biotechnology Research
Geonho Cho, Sun Min Kim, and Tae-Joon Jeon. Korean Society for Biotechnology and Bioengineering Journal 2023;38:90-9. https://doi.org/10.7841/ksbbj.2023.38.2.90
- Open Access
Elucidation of the Interactions of Reactive Oxygen Species and Antioxidants in Model Membranes Mimicking Cancer Cells and Normal Cells
Photosensitizers (PSs) used in photodynamic therapy (PDT) have been developed to selectively destroy tumor cells. However, PSs recurrently reside on the extracellular matrix or affect normal cells in the vicinity, causing side effects. Additionally, the membrane stability of tumor cells and normal cells in the presence of reactive oxygen species (ROS) has not been studied, and the effects of ROS at the membrane level are unclear. In this work, we elucidate the stabilities of model membranes mimicking tumor cells and normal cells in the presence of ROS. The model membranes are constructed according to the degree of saturation in lipids and the bilayers are prepared either in symmetric or asymmetric form. Interestingly, membranes mimicking normal cells are the most vulnerable to ROS, while membranes mimicking tumor cells remain relatively stable. The instability of normal cell membranes may be one cause of the side effects of PDT. Moreover, we also show that ROS levels are controlled by antioxidants, helping to maintain an appropriate amount of ROS when PDT is applied.
Open AccessElucidation of the Interactions of Reactive Oxygen Species and Antioxidants in Model Membranes Mimicking Cancer Cells and Normal Cells
Photosensitizers (PSs) used in photodynamic therapy (PDT) have been developed to selectively destroy tumor cells. However, PSs recurrently reside on the extracellular matrix or affect normal cells in the vicinity, causing side effects. Additionally, the membrane stability of tumor cells and normal cells in the presence of reactive oxygen species (ROS) has not been studied, and the effects of ROS at the membrane level are unclear. In this work, we elucidate the stabilities of model membranes mimicking tumor cells and normal cells in the presence of ROS. The model membranes are constructed according to the degree of saturation in lipids and the bilayers are prepared either in symmetric or asymmetric form. Interestingly, membranes mimicking normal cells are the most vulnerable to ROS, while membranes mimicking tumor cells remain relatively stable. The instability of normal cell membranes may be one cause of the side effects of PDT. Moreover, we also show that ROS levels are controlled by antioxidants, helping to maintain an appropriate amount of ROS when PDT is applied.