Carlos D. Pargas-Colina
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Previous Organizations / Institutes
The organizations / institutes from the scholar's other articles in the past ten years
Carlos D. Pargas-Colina has a total of 10 co-authors. Here are the top co-authors by number of shared publications:
- Ahmed H. Elhessy
Medicine, University of Maryland School of Medicine, Baltimore, USA
1 shared publication Benjamin W. Sheffer
University of Tennessee Health Science Center-Campbell Clinic, Department of Orthopaedic Surgery and Biomedical Engineering, Memphis, TN, USA
1 shared publicationDavid D. Spence
University of Tennessee Health Science Center-Campbell Clinic, Department of Orthopaedic Surgery and Biomedical Engineering, Memphis, TN, USA
1 shared publicationDerek M. Kelly
University of Tennessee Health Science Center-Campbell Clinic, Department of Orthopaedic Surgery and Biomedical Engineering, Memphis, TN, USA
1 shared publication- Janet D. Conway
International Center for Limb Lengthening, Rubin Institute for Advanced Orthopedics, Sinai Hospital of Baltimore, Schoeneman Building, 2nd Floor, 2401 West Belvedere Avenue, Baltimore, MD 21215, USA
1 shared publication Jonathan K. Rowland
Le Bonheur Children's Hospital, Memphis, TN, USA
1 shared publication
Latest Publications
- Open Access
- 23 May 2025
- Published by Elsevier in Journal of the Pediatric Orthopaedic Society of North America
- Vol. 12, 100200
Outcomes of Suprapatellar Intramedullary Nail Fixation of Tibial Shaft Fractures in Skeletally Immature Patients
- 23 May 2025
- Published by Elsevier in Journal of the Pediatric Orthopaedic Society of North America
- Vol. 12, 100200
Open AccessOutcomes of Suprapatellar Intramedullary Nail Fixation of Tibial Shaft Fractures in Skeletally Immature Patients
- 14 May 2024
- Published by Elsevier in Orthopedic Clinics of North America
- Vol. 55 (4) , 471-477
Transient/Toxic Synovitis
- 14 May 2024
- Published by Elsevier in Orthopedic Clinics of North America
- Vol. 55 (4) , 471-477
Transient/Toxic Synovitis
- Open Access
- 4 March 2022
- Published by MDPI AG in Antibiotics
- Vol. 11 (3) , 336
Tobramycin Blood Levels after Local Antibiotic Treatment of Bone and Soft Tissue Infection
Local antibiotic delivery using different carriers plays an important role in both infection prophylaxis and treatment. Besides dead space management, these carriers have the advantage of providing a high concentration of local antibiotics with a lower risk of systemic toxicity. Few studies have reported on systemic toxicity associated with antibiotic-impregnated carriers. The present study investigates the systemic tobramycin concentration at 24, 48 and 72 h postoperatively after using tobramycin-loaded polymethyl methacrylate (PMMA) and calcium sulfate (CS) as local antibiotic carriers. Additionally, this work assesses the renal function postoperatively for indications of acute kidney injury (AKI). Fifty-two patients were treated in 58 procedures with tobramycin and vancomycin-loaded PMMA, CS, or both. All systemic tobramycin levels were <2 mcg/mL at 72 h, and the resulting rate of AKI was 12% (7/58). In conclusion, local tobramycin antibiotic delivery using PMMA, CS, or both remains a safe and effective modality in the treatment of osteomyelitis as long as the surgeon is aware of its possible nephrotoxic effect.
- 4 March 2022
- Published by MDPI AG in Antibiotics
- Vol. 11 (3) , 336
Open AccessTobramycin Blood Levels after Local Antibiotic Treatment of Bone and Soft Tissue Infection
Local antibiotic delivery using different carriers plays an important role in both infection prophylaxis and treatment. Besides dead space management, these carriers have the advantage of providing a high concentration of local antibiotics with a lower risk of systemic toxicity. Few studies have reported on systemic toxicity associated with antibiotic-impregnated carriers. The present study investigates the systemic tobramycin concentration at 24, 48 and 72 h postoperatively after using tobramycin-loaded polymethyl methacrylate (PMMA) and calcium sulfate (CS) as local antibiotic carriers. Additionally, this work assesses the renal function postoperatively for indications of acute kidney injury (AKI). Fifty-two patients were treated in 58 procedures with tobramycin and vancomycin-loaded PMMA, CS, or both. All systemic tobramycin levels were <2 mcg/mL at 72 h, and the resulting rate of AKI was 12% (7/58). In conclusion, local tobramycin antibiotic delivery using PMMA, CS, or both remains a safe and effective modality in the treatment of osteomyelitis as long as the surgeon is aware of its possible nephrotoxic effect.