Tzu-Tung Lin

Knee osteoarthritis (OA) is a prevalent condition in older adults that often results in impaired gait and balance, increased risk of falls, and reduced quality of life. Conventional clinical assessments may not adequately capture these deficiencies. This study investigated the gait and balance of elderly individuals with knee OA using wearable inertial measurement units (IMUs). Forty-four participants with Kellgren–Lawrence grade 2–3 knee OA (71.23 ± 5.75 years) and forty-five age-matched controls (70.87 ± 4.30 years) completed dynamic balance (balance board), static balance (single-leg stance), ‘timed up and go’ (TUG), and normal walking tasks. Between 2 and 8 IMUs, depending on the task, were placed on the head, chest, waist, knees, ankles, soles, and balance board to record kinematic data. Balance was quantified using absolute angular velocity and linear acceleration, with group differences analyzed by MANOVA and Bonferroni-adjusted univariate tests. The participants with knee OA exhibited greater gait asymmetry, although the difference was not significant. However, they consistently demonstrated higher absolute angular velocities than controls across most body segments during static and dynamic tasks, indicating reduced postural stability. No group differences were observed in TUG performance. These findings suggest that IMU-based measures, particularly angular velocity, are sensitive to balance impairment detection in knee OA. Incorporating IMU technology into clinical assessments may facilitate early identification of instability and guide targeted interventions to reduce fall risk.

Balance control, a complex sensorimotor skill, declines with age. Assessing balance is crucial for identifying fall risk and implementing interventions in the older population. This study aimed to measure age-dependent changes in static and dynamic balance using inertial measurement units in a clinical setting. This study included 82 healthy participants aged 20–85 years. For the dynamic balance test, participants stood on a horizontally swaying balance board. For the static balance test, they stood on one leg. Inertial measurement units attached to their bodies recorded kinematic data, with average absolute angular velocities assessing balance capabilities. In the dynamic test, the younger participants had smaller average absolute angular velocities in most body parts than those of the middle-aged and older groups, with no significant differences between the middle-aged and older groups. Conversely, in the single-leg stance tests, the young and middle-aged groups outperformed the older group, with no significant differences between the young and middle-aged groups. Thus, dynamic and static balance decline at different stages with age. These results highlight the complementary role of inertial measurement unit-based evaluation in understanding the effect of age on postural control mechanisms, offering valuable insights for tailoring rehabilitation protocols in clinical settings.

This paper presents control design and implementation for a power-assisted mobile trainer that employs neuro-developmental treatment (NDT) principles. NDT is a gait rehabilitation technique for stroke patients that provides minimum intervention at critical gait events. Traditional NDT rehabilitation is an effective post-stroke treatment but is also time consuming and labor intensive for therapists. Therefore, we designed a mobile NDT trainer to automatically repeat therapists’ intervention patterns, allowing patients to receive sufficient training without increasing therapists’ workloads. Because the trainer was self-propelled, it could cause burdens to stroke patients with limited muscle strength, thereby potentially degrading the rehabilitation effects. Hence, this paper proposes a power-assisted device that can let the mobile trainer follow the user, allowing the subject to focus on the rehabilitation training. We conducted system identification and control design for the power-assisted NDT trainer. We then implemented the designed controllers and tested the trainer. Finally, we invited 10 healthy subjects and 12 stroke patients to conduct clinical experiments. After using the power-assisted NDT trainer, most participants exhibited improvements in swing-phase symmetry, pelvic rotation, and walking speed. Based on the results, the power-assisted device was deemed effective in facilitating stroke rehabilitation.

This paper investigates the clinical efficacy of an automatic mobile trainer for gait training in stroke patients. Neuro-Developmental Treatment (NDT) is a rehabilitation method for stroke patients that enhances motor learning through repeated practice. Despite the proven effectiveness of therapist-assisted NDT, it is labor-intensive and demands health resources. Therefore, we developed automatic trainers based on NDT principles to perform gait training. This paper modifies the mobile trainer’s intervention patterns to improve the subject’s longitudinal gait symmetry, lateral pelvic displacement symmetry, and pelvic rotation. We first invited ten healthy subjects to test the modified trainer and then recruited 26 stroke patients to undergo the same gait training. Longitudinal symmetry, lateral symmetry, and pelvic rotation were assessed before, during, and after the intervention. Most subjects show improvements in longitudinal symmetry, lateral symmetry, and pelvic rotation after using the trainer. These results confirm the trainer’s effectiveness of the modified intervention schemes in helping clinical gait rehabilitation for stroke patients.

This paper presents a clinical rehabilitation protocol for stroke patients using a movable trainer, which can automatically execute a neurodevelopmental treatment (NDT) intervention based on key gait events. The trainer consists of gait detection and motor control systems. The gait detection system applied recurrent neural networks (RNNs) to recognize important gait events in real time to trigger the motor control system to repeat the NDT intervention. This paper proposes a modified intervention method that simultaneously improves the user’s gait symmetry and pelvic rotation. We recruited ten healthy subjects and had them wear a rehabilitation gaiter on one knee joint to mimic stroke gaits for verification of the effectiveness of the trainer. We used the RNN model and a modified intervention method to increase the trainer’s effectiveness in improving gait symmetry and pelvic rotation. We then invited ten stroke patients to participate in the experiments, and we found improvement in gait symmetry in 80% and 90% of the patients during and after the training, respectively. Similarly, pelvic rotation improved in 80% of the patients during and after the training. These findings confirmed that the movable NDT trainer could improve gait performance for the rehabilitation of stroke patients.