Nicole L. Werner
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Previous Organizations / Institutes
The organizations / institutes from the scholar's other articles in the past ten years
Research Subjects
Nicole L. Werner has a total of 113 co-authors. Here are the top co-authors by number of shared publications:
- Clay Cothren Burlew
Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA
2 shared publications - Ernest Eugene Moore
Ernest E. Moore Shock Trauma Center, Denver Health, Denver, CO 80204, USA
2 shared publications Fredric M. Pieracci
Denver Health Medical Center, 777 Bannock Street, MC 0206, Denver, CO 80204 United States of America
2 shared publicationsJamie J. Coleman
Denver Health Medical Center, 777 Bannock Street, MC 0206, Denver, CO 80204 United States of America
2 shared publicationsMitchell J. Cohen
Denver Health Medical Center, 777 Bannock Street, MC 0206, Denver, CO 80204 United States of America
2 shared publications- Ryan Lawless
Denver Health Medical Center, 777 Bannock Street, MC 0206, Denver, CO 80204 United States of America
2 shared publications
Latest Publications
- 22 September 2026
- Published by Wolters Kluwer Health in Journal of Trauma and Acute Care Surgery
American Association for the Surgery of Trauma/American College of Surgeons—Committee on Trauma clinical protocol for blunt splenic injury
Level of Evidence: Therapeutic/Care Management; Level V. ( J Trauma Acute Care Surg . 2026;00: 000–000 Copyright © 2026 Wolters Kluwer Health, LLC. All rights reserved).
- 22 September 2026
- Published by Wolters Kluwer Health in Journal of Trauma and Acute Care Surgery
American Association for the Surgery of Trauma/American College of Surgeons—Committee on Trauma clinical protocol for blunt splenic injury
Level of Evidence: Therapeutic/Care Management; Level V. ( J Trauma Acute Care Surg . 2026;00: 000–000 Copyright © 2026 Wolters Kluwer Health, LLC. All rights reserved).
- Open Access
- 27 July 2026
- Published by BMJ in Trauma Surgery & Acute Care Open
- Vol. 11 (3) , e002323
Building an emergency general surgery registry to track and benchmark outcomes
Emergency general surgery (EGS) represents a significant portion of admissions to hospitals and overall surgical care delivery, yet comprehensive outcome tracking and quality improvement efforts have lagged behind elective surgery and trauma care. This article outlines the gap in data and provides three practical solutions to registry development: third-party registry software with dedicated registrars, leveraging existing National Surgical Quality Improvement Program (NSQIP) infrastructure through the EGS-NSQIP module, and automated data extraction from electronic medical records. Each approach offers unique advantages in addressing the dual challenges of case identification and risk-adjusted outcome measurement for both local quality improvement and national benchmarking. The aim of this white paper is to provide pragmatic, scalable data solutions for EGS leaders seeking to implement contemporary quality improvement and verification efforts.
- 27 July 2026
- Published by BMJ in Trauma Surgery & Acute Care Open
- Vol. 11 (3) , e002323
Open AccessBuilding an emergency general surgery registry to track and benchmark outcomes
Emergency general surgery (EGS) represents a significant portion of admissions to hospitals and overall surgical care delivery, yet comprehensive outcome tracking and quality improvement efforts have lagged behind elective surgery and trauma care. This article outlines the gap in data and provides three practical solutions to registry development: third-party registry software with dedicated registrars, leveraging existing National Surgical Quality Improvement Program (NSQIP) infrastructure through the EGS-NSQIP module, and automated data extraction from electronic medical records. Each approach offers unique advantages in addressing the dual challenges of case identification and risk-adjusted outcome measurement for both local quality improvement and national benchmarking. The aim of this white paper is to provide pragmatic, scalable data solutions for EGS leaders seeking to implement contemporary quality improvement and verification efforts.
- 25 March 2025
- Published by Wolters Kluwer Health in Journal of Trauma and Acute Care Surgery
- Vol. 98 (6) , 840-849
Contemporary management of adult splenic injuries: What you need to know
The spleen is a frequently injured organ, with over 40,000 adult splenic injuries occurring yearly. It plays an important role in the body's immune system, so surgeons should make every effort to perform splenic salvage when able. In blunt injury, indications for emergent splenectomy have not recently changed and include hemodynamic instability and peritonitis. A computed tomography (CT) scan with intravenous contrast is the preferred imaging modality for hemodynamically normal patients and should be used to classify the grade of injury and identify active bleeding and its stigmata. Nonoperative management has been successful for all grades of blunt injury (80–95%), but it is the job of the surgeon to carefully select the patient, in the context of their age, other associated injuries, and splenic CT findings, so this success rate remains high. Angioembolization is an important tool for splenic salvage that should be used when an actively bleeding vessel is observed on CT scan. Both proximal and distal embolizations are effective with no data to suggest that one is superior to the other. All patients selected for nonoperative management require close monitoring, which can include interval CT scans for high-grade injuries. Penetrating splenic injuries differ from blunt injuries because they are more likely to be surgically explored on presentation and they have a higher operative splenorrhaphy rate.
- 25 March 2025
- Published by Wolters Kluwer Health in Journal of Trauma and Acute Care Surgery
- Vol. 98 (6) , 840-849
Contemporary management of adult splenic injuries: What you need to know
The spleen is a frequently injured organ, with over 40,000 adult splenic injuries occurring yearly. It plays an important role in the body's immune system, so surgeons should make every effort to perform splenic salvage when able. In blunt injury, indications for emergent splenectomy have not recently changed and include hemodynamic instability and peritonitis. A computed tomography (CT) scan with intravenous contrast is the preferred imaging modality for hemodynamically normal patients and should be used to classify the grade of injury and identify active bleeding and its stigmata. Nonoperative management has been successful for all grades of blunt injury (80–95%), but it is the job of the surgeon to carefully select the patient, in the context of their age, other associated injuries, and splenic CT findings, so this success rate remains high. Angioembolization is an important tool for splenic salvage that should be used when an actively bleeding vessel is observed on CT scan. Both proximal and distal embolizations are effective with no data to suggest that one is superior to the other. All patients selected for nonoperative management require close monitoring, which can include interval CT scans for high-grade injuries. Penetrating splenic injuries differ from blunt injuries because they are more likely to be surgically explored on presentation and they have a higher operative splenorrhaphy rate.
- 23 October 2024
- Published by Elsevier in Current Problems in Surgery
- Vol. 61 (12) , 101648
Rib Fracture Nonunion
- 23 October 2024
- Published by Elsevier in Current Problems in Surgery
- Vol. 61 (12) , 101648
Rib Fracture Nonunion
- Open Access
- 26 March 2024
- Published by Elsevier in The American Journal of Surgery
- Vol. 234, 105-111
High-grade liver injuries with contrast extravasation managed initially with interventional radiology versus observation: A secondary analysis of a WTA multicenter study
- 26 March 2024
- Published by Elsevier in The American Journal of Surgery
- Vol. 234, 105-111
Open AccessHigh-grade liver injuries with contrast extravasation managed initially with interventional radiology versus observation: A secondary analysis of a WTA multicenter study
- Open Access
- 12 June 2023
- Published by Wolters Kluwer Health in Journal of Trauma and Acute Care Surgery
- Vol. 95 (4) , 592-602
American Association for the Surgery of Trauma/American College of Surgeons Committee on Trauma clinical protocol for management of acute respiratory distress syndrome and severe hypoxemia
LEVEL OF EVIDENCE: Therapeutic/Care Management: Level V.
- 12 June 2023
- Published by Wolters Kluwer Health in Journal of Trauma and Acute Care Surgery
- Vol. 95 (4) , 592-602
Open AccessAmerican Association for the Surgery of Trauma/American College of Surgeons Committee on Trauma clinical protocol for management of acute respiratory distress syndrome and severe hypoxemia
LEVEL OF EVIDENCE: Therapeutic/Care Management: Level V.
- 22 March 2022
- Published by Elsevier in Journal of Surgical Research
- Vol. 276, 48-53
Assessment of Discharge Analgesic Prescription Patterns for Hospitalized Patients With Rib Fractures
- 22 March 2022
- Published by Elsevier in Journal of Surgical Research
- Vol. 276, 48-53
Assessment of Discharge Analgesic Prescription Patterns for Hospitalized Patients With Rib Fractures
- 4 November 2015
- Published by Wiley in Prenatal Diagnosis
- Vol. 36 (2) , 107-111
Prenatal and postnatal markers of severity in congenital diaphragmatic hernia have similar prognostic ability
Objectives: The purpose of this study was to compare prenatal versus postnatal markers of congenital diaphragmatic hernia (CDH) severity at a single fetal‐care center.Methods: A retrospective study was performed of patients having a complete prenatal evaluation and surgical repair (n = 55). Observed‐to‐expected lung‐to‐head ratio (o/eLHR), observed‐to‐expected total lung volume (o/eTLV), liver position (LP), a predictive dependent variable from logistic regression of o/eLHR and liver position (o/eLHR + LP), and diaphragmatic defect size per the CDH Study Group A–D classification were plotted into receiver–operating characteristics (ROC) curves. Survival and need for extracorporeal membrane oxygenation (ECMO) were primary outcomes.Results: Survival was 69%, and ECMO utilization was 56%. Distribution was 80% left‐sided defects. In the survival ROC curve, the area under the curve (AUC) for o/eLHR was 0.73, o/eTLV 0.74, LP 0.73, o/eLHR + LP 0.78, and defect size 0.84 (p = 0.23). The ROC curve for ECMO support showed o/eLHR had an AUC of 0.82, o/eTLV 0.89, LP 0.79, o/eLHR + LP 0.87, and defect size 0.90 (p = 0.19). The AUCs were similar when only left‐sided CDH was analyzed.Conclusions: These data suggest that prenatal evaluation was equivalent to the postnatal diaphragmatic defect classification for predicting survival and need for ECMO in CDH patients. © 2015 John Wiley & Sons, Ltd.
- 4 November 2015
- Published by Wiley in Prenatal Diagnosis
- Vol. 36 (2) , 107-111
Prenatal and postnatal markers of severity in congenital diaphragmatic hernia have similar prognostic ability
Objectives: The purpose of this study was to compare prenatal versus postnatal markers of congenital diaphragmatic hernia (CDH) severity at a single fetal‐care center.Methods: A retrospective study was performed of patients having a complete prenatal evaluation and surgical repair (n = 55). Observed‐to‐expected lung‐to‐head ratio (o/eLHR), observed‐to‐expected total lung volume (o/eTLV), liver position (LP), a predictive dependent variable from logistic regression of o/eLHR and liver position (o/eLHR + LP), and diaphragmatic defect size per the CDH Study Group A–D classification were plotted into receiver–operating characteristics (ROC) curves. Survival and need for extracorporeal membrane oxygenation (ECMO) were primary outcomes.Results: Survival was 69%, and ECMO utilization was 56%. Distribution was 80% left‐sided defects. In the survival ROC curve, the area under the curve (AUC) for o/eLHR was 0.73, o/eTLV 0.74, LP 0.73, o/eLHR + LP 0.78, and defect size 0.84 (p = 0.23). The ROC curve for ECMO support showed o/eLHR had an AUC of 0.82, o/eTLV 0.89, LP 0.79, o/eLHR + LP 0.87, and defect size 0.90 (p = 0.19). The AUCs were similar when only left‐sided CDH was analyzed.Conclusions: These data suggest that prenatal evaluation was equivalent to the postnatal diaphragmatic defect classification for predicting survival and need for ECMO in CDH patients. © 2015 John Wiley & Sons, Ltd.