Daniela Medeiros Lobo de Andrade

Growing concerns on free radicals are the oxidative processes associated with physiological damage. The consumption of functional foods and use of plants with antioxidant capacity are widespread. Given the importance of determining antioxidant capacity in relation to the therapeutic effect, this study was aimed at evaluating cinnamon extract (Cinnamomum sp.) in commercial samples by spectrophotometric and voltammetric methods and assessing the vascular activity of some samples. The spectrophotometric methods performed were DPPH (1,1‐diphenyl‐2‐picrihydrazine), ABTS (2,21‐azinobis‐(3‐ethylbenzothiazoline‐6‐sulfonic acid)), and Folin‐Ciocalteu radical sequestration assays. For the electrochemical experiments, a three‐electrode system was used, consisting of carbon paste electrode, platinum wire, and Ag/AgCl/KCl_sat, representing the working, auxiliary, and reference electrodes, respectively. The electroanalytical methods used were differential pulse, square wave, and cyclic voltammetries. The extracts were prepared in hydroalcoholic solution. A calibration curve with gallic acid was calculated to quantify their equivalent amounts in the analyzed extract. The correlation between the electrochemical approach and the total phenols calculated by the ABTS, DPPH, and Folin‐Ciocalteu methods was 0.63, 0.7, and 0.73, respectively, with 1 being an ideal directly proportional correlation. The correlation between spectrophotometric methods was 0.83. A biosensor was developed in a carbon paste electrode using the enzyme laccase, obtained by the fungus Marasmiellus colocasiae. It was observed that the antioxidant profile of the cinnamon samples had an analytical sign improvement of up to 4 times when compared with the electrode without the modification. The samples were analyzed by mass spectrometer, and the main chemical markers found were coumarin, cinnamaldehyde, and eugenol. Pharmacological trials showed that these samples also induce a significant vasorelaxant effect associated to antioxidant potential on vascular injury induced by oxidative stress. Thus, cinnamon showed a high antioxidant capacity, in agreement with the results obtained in other studies, emphasizing its importance as a functional food.

Os cuidados com a pele contra a radiação solar, a fotoproteção, são essenciais devido aos altos índices de casos de câncer de pele no Brasil, incluindo o estado de Goiás. Assim, atividades de educação em saúde acerca do uso correto de filtros solares devem ser realizadas. Esse trabalho apresenta os resultados da Campanha Nacional de Fotoeducação (CNF), organizada pelo Fórum Nacional de Farmácias Universitárias (FNFU), realizada no estado de Goiás (CNF/FNFU-GO). O evento foi organizado e realizado por professores e estudantes do curso de Farmácia de cinco instituições de ensino superior, em novembro/2018, em Goiânia (GO). Os estudantes foram capacitados por meio de palestras educativas, abordando diferentes tópicos sobre medidas de fotoproteção e cuidados da pele, e elaboraram jogos educativos. Os locais das ações educativas foram estrategicamente escolhidos: região de alto fluxo de pessoas e/ou com atividades de lazer em ambiente aberto, e trabalhadores com frequente exposição à luz solar. A CNF/FNFU-GO orientou um público estimado de 650 pessoas, entre crianças e adultos, com olhar multidisciplinar, destacando a relação entre o cuidado farmacêutico, epidemiologia, farmacotécnica, cosmetologia e toxicologia. Um quiz com 10 perguntas foi desenvolvido, o que proporcionou uma interação e troca de conhecimentos com a comunidade, de forma extremamente receptiva. Os alunos relataram grande satisfação e aprendizado ao participar da CNF/FNFU-GO. A participação dos estudantes de Farmácia em experiências práticas de educação em saúde promoveu novos conhecimentos, habilidades humanizadas, valores e atitudes excepcionais com a comunidade, assim como o fornecimento de informações de qualidade à população. Palavras-chave: Aprendizagem por Competências; Fotoeducação; Interdisciplinaridade; Protetores Solares; Radiação Solar Pharmaceutical care in photoprotection: health education actions in the Goiás state Abstract: Skincare against solar radiation, namely photoprotection, is essential due to the high rates of skin cancer in Brazil, including the Goiás state. Thus, health education activities regarding the correct use of sunscreens should be carried out. This study shows the results of the National Campaign for Photo-Education (CNF), organized by the National Forum of University Pharmacies (FNFU), held in the Goiás state (CNF/FNFU-GO). The event was organized by Pharmacy undergraduate educators and students from five higher education institutions in November 2018 in Goiânia, GO, Brazil. The students were trained through educational lectures, which focused on different topics regarding measures of photoprotection and skincare, and educational games were elaborated. The places of educational actions were strategically chosen: a high flow of people and outdoor recreation, and workers with frequent solar exposure. The CNF/FNFU-GO oriented an estimated public of 650 people, among children and adults, with a multidisciplinary approach by highlighting the relationship between pharmaceutical care, epidemiology, pharmacotechnics, cosmetology, and toxicology. In addition, a ten-question quiz was developed, which provided an interaction and knowledge exchange with the community in a highly receptive way. The students reported great satisfaction and learning when participating in the CNF/FNFU-GO. The participation of Pharmacy undergraduate students in practical health education experiences promoted new knowledge, humanized skills, exceptional values, and attitudes with the community, as well as providing quality information to the population. Keywords: Competence Learning; Photoeducation; Interdisciplinarity; Sunscreens; Solar Radiation