SeungMin Song
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Previous Organizations / Institutes
The organizations / institutes from the scholar's other articles in the past ten years
SeungMin Song has a total of 8 co-authors. Here are the top co-authors by number of shared publications:
- Woo Kyoung Kim
Department of Food Science and Nutrition, Dankook University, Cheonan 31116, Korea
2 shared publications - Ae Wha Ha
Department of Food Science and Nutrition, Dankook University, Cheonan 31116, Korea
1 shared publication - Khuhee Na
Department of Nutritional Science and Food Management, Ewha Womans University, Seoul 03760, Republic of Korea
1 shared publication - So Young Kwon
Graduate Program in System Health & Engineering, Ewha Womans University, Seoul 03760, Korea
1 shared publication - Soo Min Jung
Department of Food Science and Nutrition, Dankook University, Cheonan 31116, Korea
1 shared publication - Su Jin Choi
Department of Food Science and Nutrition, College of Science and Technology, Dankook University
1 shared publication
Latest Publications
- Open Access
- 1 January 2026
- Published by XMLink in Nutrition Research and Practice
- Vol. 20 (2) , 220-238
Nicotinamide mononucleotide attenuates hepatic endoplasmic reticulum stress and modulates circadian rhythms in young mice with diet-induced obesity
Supplementation of nicotinamide adenine dinucleotide (NAD) precursors has been investigated for its potential to counteract age-related physiological decline. While decreased NAD+ level is associated with conditions such as obesity and dyslipidemia, few studies have explored its metabolic impact in relatively young animals. Here, we hypothesized that nicotinamide mononucleotide (NMN) could alleviate high-fat diet-induced metabolic stress in young mice and sought to elucidate the underlying mechanisms. We first conducted a secondary analysis of hepatic transcriptome datasets from multiple NMN intervention studies to identify target pathways. Next, 11-week-old lean and obese C57BL/6N mice administrated NMN (500 mg/kg/day) for 1 mon were analyzed for metabolic parameters and gene expression for the target pathways. In vitro study using AML12 cell line was then conducted to confirm the effects of NMN. Additionally, transcriptomic data from liver-specific nicotinamide phosphoribosyltransferase (NAMPT)-deficient mice were analyzed to examine the relationship between NAD+ metabolism, endoplasmic reticulum (ER) stress, and circadian rhythm. The secondary analysis of hepatic transcriptome datasets revealed potential target pathways related to circadian regulation and hepatic ER stress. In mouse study, short-term NMN administration significantly decreased body weight and fat mass. NMN also alleviated hepatic ER stress response in vivo and in vitro. Additional analysis revealed that the mice with diet-induced metabolic stress or NAMPT deficiency led to phase shifts of the hepatic circadian core clock oscillation by advancing the peak time, while time-restricted feeding shifted the opposite, indicating the metabolic regulation of the circadian phase. Short-term NMN administration effectively attenuated obese condition in young mice and mitigated hepatic ER stress. The altered ER stress was regulated by NAMPT, potentially through the phase shift of the hepatic circadian rhythm.
- 1 January 2026
- Published by XMLink in Nutrition Research and Practice
- Vol. 20 (2) , 220-238
Open AccessNicotinamide mononucleotide attenuates hepatic endoplasmic reticulum stress and modulates circadian rhythms in young mice with diet-induced obesity
Supplementation of nicotinamide adenine dinucleotide (NAD) precursors has been investigated for its potential to counteract age-related physiological decline. While decreased NAD+ level is associated with conditions such as obesity and dyslipidemia, few studies have explored its metabolic impact in relatively young animals. Here, we hypothesized that nicotinamide mononucleotide (NMN) could alleviate high-fat diet-induced metabolic stress in young mice and sought to elucidate the underlying mechanisms. We first conducted a secondary analysis of hepatic transcriptome datasets from multiple NMN intervention studies to identify target pathways. Next, 11-week-old lean and obese C57BL/6N mice administrated NMN (500 mg/kg/day) for 1 mon were analyzed for metabolic parameters and gene expression for the target pathways. In vitro study using AML12 cell line was then conducted to confirm the effects of NMN. Additionally, transcriptomic data from liver-specific nicotinamide phosphoribosyltransferase (NAMPT)-deficient mice were analyzed to examine the relationship between NAD+ metabolism, endoplasmic reticulum (ER) stress, and circadian rhythm. The secondary analysis of hepatic transcriptome datasets revealed potential target pathways related to circadian regulation and hepatic ER stress. In mouse study, short-term NMN administration significantly decreased body weight and fat mass. NMN also alleviated hepatic ER stress response in vivo and in vitro. Additional analysis revealed that the mice with diet-induced metabolic stress or NAMPT deficiency led to phase shifts of the hepatic circadian core clock oscillation by advancing the peak time, while time-restricted feeding shifted the opposite, indicating the metabolic regulation of the circadian phase. Short-term NMN administration effectively attenuated obese condition in young mice and mitigated hepatic ER stress. The altered ER stress was regulated by NAMPT, potentially through the phase shift of the hepatic circadian rhythm.
- Open Access
- 1 January 2023
- Published by XMLink in Nutrition Research and Practice
- Vol. 17 (3) , 438-450
Quercetin inhibits body weight gain and adipogenesis via matrix metalloproteinases in mice fed a high-fat diet
Song S, et al. Nutr Res Pract. 2023 Jun;17(3):438-450. https://doi.org/10.4162/nrp.2023.17.3.438
- 1 January 2023
- Published by XMLink in Nutrition Research and Practice
- Vol. 17 (3) , 438-450
Open AccessQuercetin inhibits body weight gain and adipogenesis via matrix metalloproteinases in mice fed a high-fat diet
Song S, et al. Nutr Res Pract. 2023 Jun;17(3):438-450. https://doi.org/10.4162/nrp.2023.17.3.438
- Open Access
- 30 April 2022
- Published by The Korean Society of Food Science and Nutrition in Journal of the Korean Society of Food Science and Nutrition
- Vol. 51 (4) , 311-321
Quercetin Inhibits Adipocyte Differentiation via Matrix Metalloproteinases in 3T3-L1 Preadipocytes
Seung Min Song, Soo Min Jung, Su Jin Choi, and Woo Kyoung Kim. Journal of the Korean Society of Food Science and Nutrition 2022;51:311-21. https://doi.org/10.3746/jkfn.2022.51.4.311
- 30 April 2022
- Published by The Korean Society of Food Science and Nutrition in Journal of the Korean Society of Food Science and Nutrition
- Vol. 51 (4) , 311-321
Open AccessQuercetin Inhibits Adipocyte Differentiation via Matrix Metalloproteinases in 3T3-L1 Preadipocytes
Seung Min Song, Soo Min Jung, Su Jin Choi, and Woo Kyoung Kim. Journal of the Korean Society of Food Science and Nutrition 2022;51:311-21. https://doi.org/10.3746/jkfn.2022.51.4.311