Hongyu Xie
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Hongyu Xie has a total of 9 co-authors. Here are the top co-authors by number of shared publications:
- Gang Liu
Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China
1 shared publication - Jie Jia
Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai, China
1 shared publication - Jingjie Ge
Department of Nuclear Medicine, Huashan Hospital, Fudan University, 518 East Wuzhong Road, Shanghai 200235, China
1 shared publication - Junfa Wu
Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China
1 shared publication - Rongrong Lu
Department of Rehabilitation, Huashan Hospital, Fudan University, Shanghai, China
1 shared publication - Yi Wu
Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China
1 shared publication
Latest Publications
- Open Access
- 7 July 2022
- Published by MDPI AG in Brain Sciences
- Vol. 12 (7) , 892
Brain Metabolic Connectivity Patterns in Patients with Prolonged Disorder of Consciousness after Hypoxic-Ischemic Injury: A Preliminary Study
Understanding the patterns of brain glucose metabolism and connectivity in hypoxic-ischemic encephalopathy (HIE) patients with prolonged disorders of consciousness (DOC) may be of positive significance to the accurate assessment of consciousness and the optimization of neuromodulation strategy. We retrospectively analyzed the brain glucose metabolism pattern and its correlation with clinical Coma Recovery Scale-Revised (CRS-R) score in six HIE patients with prolonged DOC who had undergone 18F-deoxyglucose brain positron emission tomography scanning (FDG-PET). We also compared the differences in global metabolic connectivity patterns and the characteristics of several brain networks between HIE patients and healthy controls (HC). The metabolism of multiple brain regions decreased significantly in HIE patients, and the degree of local metabolic preservation was correlated with CRS-R score. The internal metabolic connectivity of occipital lobe and limbic system in HIE patients decreased, and their metabolic connectivity with frontal lobe, parietal lobe and temporal lobe also decreased. The metabolic connectivity patterns of default mode network, dorsal attention network, salience network, executive control network and subcortex network of HIE also changed compared with HC. The present study suggested that pattern of cerebral glucose metabolism and network connectivity of HIE patients with prolonged DOC were significantly different from those of healthy people.
- 7 July 2022
- Published by MDPI AG in Brain Sciences
- Vol. 12 (7) , 892
Open AccessBrain Metabolic Connectivity Patterns in Patients with Prolonged Disorder of Consciousness after Hypoxic-Ischemic Injury: A Preliminary Study
Understanding the patterns of brain glucose metabolism and connectivity in hypoxic-ischemic encephalopathy (HIE) patients with prolonged disorders of consciousness (DOC) may be of positive significance to the accurate assessment of consciousness and the optimization of neuromodulation strategy. We retrospectively analyzed the brain glucose metabolism pattern and its correlation with clinical Coma Recovery Scale-Revised (CRS-R) score in six HIE patients with prolonged DOC who had undergone 18F-deoxyglucose brain positron emission tomography scanning (FDG-PET). We also compared the differences in global metabolic connectivity patterns and the characteristics of several brain networks between HIE patients and healthy controls (HC). The metabolism of multiple brain regions decreased significantly in HIE patients, and the degree of local metabolic preservation was correlated with CRS-R score. The internal metabolic connectivity of occipital lobe and limbic system in HIE patients decreased, and their metabolic connectivity with frontal lobe, parietal lobe and temporal lobe also decreased. The metabolic connectivity patterns of default mode network, dorsal attention network, salience network, executive control network and subcortex network of HIE also changed compared with HC. The present study suggested that pattern of cerebral glucose metabolism and network connectivity of HIE patients with prolonged DOC were significantly different from those of healthy people.