Beatrice Gallo
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Beatrice Gallo has a total of 9 co-authors. Here are the top co-authors by number of shared publications:
- Adam P. Januszewski
National Heart and Lung Institute, Imperial College London, London SW3 6LR, UK
1 shared publication - Anca Nastase
National Heart and Lung Institute, Imperial College London, London, UK
1 shared publication - Anne M. Bowcock
Icahn School of Medicine at Mount Sinai, New York, New York
1 shared publication - Caroline Thaung
University College London, Institute of Ophthalmology, London, United Kingdom
1 shared publication - David J. Essex
Ocular Oncology Service, Moorfields Eye Hospital & St. Bartholomew’s Hospital, London EC1V 2PD, UK
1 shared publication - Mandeep S. Sagoo
Ocular Oncology Service, Moorfields Eye Hospital NHS Foundation Trust, London, UK
1 shared publication
Latest Publications
- Open Access
Correlation between BAP1 Localization, Driver Mutations, and Patient Survival in Uveal Melanoma
Uveal melanoma (UM) is an uncommon but highly aggressive ocular malignancy. Poor overall survival is associated with deleterious BAP1 alterations, which frequently occur with monosomy 3 (LOH3) and a characteristic gene expression profile. Tumor DNA from a cohort of 100 UM patients from Moorfields Biobank (UK) that had undergone enucleation were sequenced for known UM driver genes (BAP1, SF3B1, EIF1AX, GNAQ, and GNA11). Immunohistochemical staining of BAP1 and interphase FISH for chromosomes 3 and 8 was performed, and cellular localization of BAP1 was correlated with BAP1 mutations. Wildtype (WT) BAP1 staining was characterized by nBAP1 expression with 10% cBAP1.
Open AccessCorrelation between BAP1 Localization, Driver Mutations, and Patient Survival in Uveal Melanoma
Uveal melanoma (UM) is an uncommon but highly aggressive ocular malignancy. Poor overall survival is associated with deleterious BAP1 alterations, which frequently occur with monosomy 3 (LOH3) and a characteristic gene expression profile. Tumor DNA from a cohort of 100 UM patients from Moorfields Biobank (UK) that had undergone enucleation were sequenced for known UM driver genes (BAP1, SF3B1, EIF1AX, GNAQ, and GNA11). Immunohistochemical staining of BAP1 and interphase FISH for chromosomes 3 and 8 was performed, and cellular localization of BAP1 was correlated with BAP1 mutations. Wildtype (WT) BAP1 staining was characterized by nBAP1 expression with 10% cBAP1.