Laura Rosa
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Laura Rosa has a total of 15 co-authors. Here are the top co-authors by number of shared publications:
- Alessandro Chiodi
Intradepartmental Program of Clinical Psychology, Federico II University Hospital, 80131 Naples, Italy
1 shared publication - Antonio Carotenuto
Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples, Italy
1 shared publication - Antonio Luca Spiezia
Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, 80131 Naples, Italy
1 shared publication - Carmine Iacovazzo
Anesthesia and Intensive Care Medicine, Department of Neuroscience, Reproductive Sciences and Odontostomatological Sciences, University of Naples “Federico II”, Naples, Italy
1 shared publication - Francesca Dicé
Department of Human Studies, University of Naples Federico II, 80138 Naples, Italy
1 shared publication - Francesca Lauro
Department of Neurosciences and Reproductive and Odontostomatological Sciences, University of Naples Federico II, 80131 Naples, Italy
1 shared publication
Latest Publications
- Open Access
- 4 September 2022
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 11 (17) , 5226
Quality of Life Changes in Early-Onset Multiple Sclerosis: A 4-Year Follow-Up Study
This study investigates longitudinal changes in health-related quality of life (HRQoL) in early-onset multiple sclerosis (MS) patients and explores the impact of disease activity (relapses) on such changes. People with MS (PwMS) onset between 12 and 25 years of age were followed longitudinally. At baseline and at year 4, patients were asked to fill the Paediatric Quality of life inventory (PedsQL). Demographic and clinical features were collected at both time points. Longitudinal within-group comparison of HRQoL total score and sub-scores was performed via paired samples t-test. The effect of relapses on the HRQoL changes over time was explored via linear mixed-effects analysis. No longitudinal changes were observed in the overall PedsQL score, nor in the physical, school and psychological functioning. An increase in the social functioning subscale (p < 0.001) and a decrease in the emotional subscale (p = 0.006) were observed. The change in social functioning, but not the one in the emotional subscale, was affected by the occurrence of relapses (p = 0.044). In conclusion, stimulating the patients to accept their emotional responses to health-related limitations, while preserving their social and relational resources seems key to the preservation of an adequate QoL over time in juvenile-onset MS.
- 4 September 2022
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 11 (17) , 5226
Open AccessQuality of Life Changes in Early-Onset Multiple Sclerosis: A 4-Year Follow-Up Study
This study investigates longitudinal changes in health-related quality of life (HRQoL) in early-onset multiple sclerosis (MS) patients and explores the impact of disease activity (relapses) on such changes. People with MS (PwMS) onset between 12 and 25 years of age were followed longitudinally. At baseline and at year 4, patients were asked to fill the Paediatric Quality of life inventory (PedsQL). Demographic and clinical features were collected at both time points. Longitudinal within-group comparison of HRQoL total score and sub-scores was performed via paired samples t-test. The effect of relapses on the HRQoL changes over time was explored via linear mixed-effects analysis. No longitudinal changes were observed in the overall PedsQL score, nor in the physical, school and psychological functioning. An increase in the social functioning subscale (p < 0.001) and a decrease in the emotional subscale (p = 0.006) were observed. The change in social functioning, but not the one in the emotional subscale, was affected by the occurrence of relapses (p = 0.044). In conclusion, stimulating the patients to accept their emotional responses to health-related limitations, while preserving their social and relational resources seems key to the preservation of an adequate QoL over time in juvenile-onset MS.