Alireza Karimpour
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Interests
Alireza Karimpour has a total of 8 co-authors. Here are the top co-authors by number of shared publications:
- Abdollah Maleki
Non-Destructive Testing Lab, Department of Mechanical Engineering, Amirkabir University of Technology, 424 Hafez Ave, Tehran 15914, Iran
1 shared publication - Elaheh Dalir Abdolahinia
Department of Oral Science and Translation Research, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA
1 shared publication - Elham Ahmadian
Kidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
1 shared publication - Khang Wen Goh
Faculty of Data Science and Information Technology INTI International University Nilai Malaysia
1 shared publication - Mohammad Ali Ghavimi
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran
1 shared publication - Mohammad Yousef Memar
Infectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz 5166, Iran
1 shared publication
Latest Publications
- Open Access
- 30 September 2022
- Published by MDPI AG in Nanomaterials
- Vol. 12 (19) , 3436
A Biodegradable Flexible Micro/Nano-Structured Porous Hemostatic Dental Sponge
A biodegradable micro/nano-structured porous hemostatic gelatin-based sponge as a dentistry surgery foam was prepared using a freeze-drying method. In vitro function evaluation tests were performed to ensure its hemostatic effect. Biocompatibility tests were also performed to show the compatibility of the sponge on human fetal foreskin fibroblasts (HFFF2) cells and red blood cells (RBCs). Then, 10 patients who required the extraction of two teeth were selected, and after teeth extraction, for dressing, the produced sponge was placed in one of the extracavities while a commercial sponge was placed in the cavity in the other tooth as a control. The total weight of the absorbed blood in each group was compared. The results showed a porous structure with micrometric and nanometric pores, flexibility, a two-week range for degradation, and an ability to absorb blood 35 times its weight in vitro. The prepared sponge showed lower blood clotting times (BCTs) (243.33 ± 2.35 s) and a lower blood clotting index (BCI) (10.67 ± 0.004%) compared to two commercial sponges that displayed its ability for faster coagulation and good hemostatic function. It also had no toxic effects on the HFFF2 cells and RBCs. The clinical assessment showed a better ability of blood absorption for the produced sponge (p-value = 0.0015). The sponge is recommended for use in dental surgeries because of its outstanding abilities.
- 30 September 2022
- Published by MDPI AG in Nanomaterials
- Vol. 12 (19) , 3436
Open AccessA Biodegradable Flexible Micro/Nano-Structured Porous Hemostatic Dental Sponge
A biodegradable micro/nano-structured porous hemostatic gelatin-based sponge as a dentistry surgery foam was prepared using a freeze-drying method. In vitro function evaluation tests were performed to ensure its hemostatic effect. Biocompatibility tests were also performed to show the compatibility of the sponge on human fetal foreskin fibroblasts (HFFF2) cells and red blood cells (RBCs). Then, 10 patients who required the extraction of two teeth were selected, and after teeth extraction, for dressing, the produced sponge was placed in one of the extracavities while a commercial sponge was placed in the cavity in the other tooth as a control. The total weight of the absorbed blood in each group was compared. The results showed a porous structure with micrometric and nanometric pores, flexibility, a two-week range for degradation, and an ability to absorb blood 35 times its weight in vitro. The prepared sponge showed lower blood clotting times (BCTs) (243.33 ± 2.35 s) and a lower blood clotting index (BCI) (10.67 ± 0.004%) compared to two commercial sponges that displayed its ability for faster coagulation and good hemostatic function. It also had no toxic effects on the HFFF2 cells and RBCs. The clinical assessment showed a better ability of blood absorption for the produced sponge (p-value = 0.0015). The sponge is recommended for use in dental surgeries because of its outstanding abilities.