Malin Ström
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Malin Ström has a total of 6 co-authors. Here are the top co-authors by number of shared publications:
- Krister Lindmark
Karolinska Institute
1 shared publication - Martin Maripuu
Department of Clinical Sciences, Division of Psychiatry, Umeå University, Umeå, Sweden
1 shared publication - Michael Ott
Department of Public Health and clinical Medicine, Umea University, Umea, Sweden
1 shared publication - Petra Truedson
Sunderby Research Unit, Department of Clinical Sciences/Psychiatry, Umeå University, Umeå, Sweden
1 shared publication - Robert Lundqvist
Research and Innovation Unit, Norrbotten County Council, Luleå, Sweden
1 shared publication - Ursula Werneke
Department of Clinical Sciences, Division of Psychiatry, Sunderby Research Unit, Umeå University, Umeå, Sweden
1 shared publication
Latest Publications
- Open Access
- 8 October 2022
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 11 (19) , 5941
Effects of Toxic Lithium Levels on ECG—Findings from the LiSIE Retrospective Cohort Study
(1) Background: Few studies have explored the impact of lithium intoxication on the heart. (2) Methods: We examined electrocardiogram (ECG) changes associated with lithium intoxication in the framework of the LiSIE (Lithium—Study into Effects and Side Effects) retrospective cohort study. We analysed ECGs before, during, and after intoxication. (3) Results: Of the 1136 patients included, 92 patients had experienced 112 episodes of lithium intoxication. For 55 episodes, there was an ECG available at the time; for 48 episodes, there was a reference ECG available before and/or after the lithium intoxication. Lithium intoxication led to a statistically significant decrease in heart rate from a mean 76 beats/min (SD 16.6) before intoxication to 73 beats/min (SD 17.1) during intoxication (p = 0.046). QTc correlated only weakly with lithium concentration (ρ = 0.329, p = 0.014). However, in 24% of lithium intoxication episodes, there were QT prolongations. In 54% of these, QTc exceeded 500 ms; patients with chronic intoxications being more affected. (4) Conclusions: Based on summary statistics, effects of lithium intoxication on HR and QTc seem mostly discrete and not clinically relevant. However, QT prolongation can carry a risk of becoming severe. Therefore, an ECG should always be taken in patients presenting with lithium intoxication.
- 8 October 2022
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 11 (19) , 5941
Open AccessEffects of Toxic Lithium Levels on ECG—Findings from the LiSIE Retrospective Cohort Study
(1) Background: Few studies have explored the impact of lithium intoxication on the heart. (2) Methods: We examined electrocardiogram (ECG) changes associated with lithium intoxication in the framework of the LiSIE (Lithium—Study into Effects and Side Effects) retrospective cohort study. We analysed ECGs before, during, and after intoxication. (3) Results: Of the 1136 patients included, 92 patients had experienced 112 episodes of lithium intoxication. For 55 episodes, there was an ECG available at the time; for 48 episodes, there was a reference ECG available before and/or after the lithium intoxication. Lithium intoxication led to a statistically significant decrease in heart rate from a mean 76 beats/min (SD 16.6) before intoxication to 73 beats/min (SD 17.1) during intoxication (p = 0.046). QTc correlated only weakly with lithium concentration (ρ = 0.329, p = 0.014). However, in 24% of lithium intoxication episodes, there were QT prolongations. In 54% of these, QTc exceeded 500 ms; patients with chronic intoxications being more affected. (4) Conclusions: Based on summary statistics, effects of lithium intoxication on HR and QTc seem mostly discrete and not clinically relevant. However, QT prolongation can carry a risk of becoming severe. Therefore, an ECG should always be taken in patients presenting with lithium intoxication.