Samuel M. Borer
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Interests
Samuel M. Borer has a total of 14 co-authors. Here are the top co-authors by number of shared publications:
- Aleta R. Steevens
University of Minnesota
1 shared publication - Alex Roman
Graduate Program in Neuroscience, University of Minnesota, Minneapolis, MN 55455, USA
1 shared publication - Anala Shetty
University of Minnesota
1 shared publication - Andrew Walker Grande
Department of Neurosurgery, University of Minnesota, Minneapolis, MN, USA
1 shared publication - Emily G. Fellows
Department of Neurosurgery, University of Minnesota, Minneapolis, MN 55455, USA
1 shared publication - Isaac H. Clark
Biomedical Engineering Graduate Program, United States
1 shared publication
Latest Publications
- Open Access
- 17 October 2022
- Published by MDPI AG in Biomedicines
- Vol. 10 (10) , 2598
Cell Reprogramming for Regeneration and Repair of the Nervous System
A persistent barrier to the cure and treatment of neurological diseases is the limited ability of the central and peripheral nervous systems to undergo neuroregeneration and repair. Recent efforts have turned to regeneration of various cell types through cellular reprogramming of native cells as a promising therapy to replenish lost or diminished cell populations in various neurological diseases. This review provides an in-depth analysis of the current viral vectors, genes of interest, and target cellular populations that have been studied, as well as the challenges and future directions of these novel therapies. Furthermore, the mechanisms by which cellular reprogramming could be optimized as treatment in neurological diseases and a review of the most recent cellular reprogramming in vitro and in vivo studies will also be discussed.
- 17 October 2022
- Published by MDPI AG in Biomedicines
- Vol. 10 (10) , 2598
Open AccessCell Reprogramming for Regeneration and Repair of the Nervous System
A persistent barrier to the cure and treatment of neurological diseases is the limited ability of the central and peripheral nervous systems to undergo neuroregeneration and repair. Recent efforts have turned to regeneration of various cell types through cellular reprogramming of native cells as a promising therapy to replenish lost or diminished cell populations in various neurological diseases. This review provides an in-depth analysis of the current viral vectors, genes of interest, and target cellular populations that have been studied, as well as the challenges and future directions of these novel therapies. Furthermore, the mechanisms by which cellular reprogramming could be optimized as treatment in neurological diseases and a review of the most recent cellular reprogramming in vitro and in vivo studies will also be discussed.