Ke Sun
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Ke Sun has a total of 4 co-authors. Here are the top co-authors by number of shared publications:
- Fan Yu
College of Life Sciences, Nankai University, Weijin Road, Nankai District, Tianjin 300350, China
1 shared publication - Hongzhen Jin
State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Drug Research and KLMDASR of Tianjin, College of Pharmacy, Nankai University, Tianjin 300350, China
1 shared publication - Wei Zhao
State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Key Laboratory of Molecular Drug Research and KLMDASR of Tianjin, Nankai University
1 shared publication - Xue Zheng
College of Pharmacy, Nankai University, Tongyan Road, Haihe Education Park, Tianjin 300350, China
1 shared publication
Latest Publications
- Open Access
- 21 October 2022
- Published by MDPI AG in Pharmaceutics
- Vol. 14 (10) , 2252
Exosomes as CNS Drug Delivery Tools and Their Applications
Central nervous system (CNS) diseases threaten the health of people all over the world. However, due to the structural and functional particularities of the brain and spinal cord, CNS-targeted drug development is rather challenging. Exosomes are small cellular vesicles with lipid bilayers that can be secreted by almost all cells and play important roles in intercellular communication. The advantages of low immunogenicity, the ability to cross the blood-brain barrier, and the flexibility of drug encapsulation make them stand out among CNS drug delivery tools. Herein, we reviewed the research on exosomes in CNS drug delivery over the past decade and outlined the impact of the drug loading mode, administration route, and engineered modification on CNS targeting. Finally, we highlighted the problems and prospects of exosomes as CNS drug delivery tools.
- 21 October 2022
- Published by MDPI AG in Pharmaceutics
- Vol. 14 (10) , 2252
Open AccessExosomes as CNS Drug Delivery Tools and Their Applications
Central nervous system (CNS) diseases threaten the health of people all over the world. However, due to the structural and functional particularities of the brain and spinal cord, CNS-targeted drug development is rather challenging. Exosomes are small cellular vesicles with lipid bilayers that can be secreted by almost all cells and play important roles in intercellular communication. The advantages of low immunogenicity, the ability to cross the blood-brain barrier, and the flexibility of drug encapsulation make them stand out among CNS drug delivery tools. Herein, we reviewed the research on exosomes in CNS drug delivery over the past decade and outlined the impact of the drug loading mode, administration route, and engineered modification on CNS targeting. Finally, we highlighted the problems and prospects of exosomes as CNS drug delivery tools.