Fu-Jun Chen
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Fu-Jun Chen has a total of 7 co-authors. Here are the top co-authors by number of shared publications:
- Chung Yi Hsu
Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan
1 shared publication - Min-Hua Lin
Department of Nutrition, China Medical University, Taichung 40402, Taiwan
1 shared publication - Ming-Chien Yin
Division of Respiratory Therapy, China Medical University Hospital, Taichung 404327, Taiwan
1 shared publication - Pau-Chung Chen
Department of Environmental and Occupational Medicine, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan
1 shared publication - Pei-Yun Chen
Departmant of public Health, China Medical University, Taichung, Taiwan
1 shared publication - Wen-Chao Ho
Department of Public Health, China Medical University, Taichung 406040, Taiwan
1 shared publication
Latest Publications
- Open Access
- 23 October 2022
- Published by MDPI AG in International Journal of Environmental Research and Public Health
- Vol. 19 (21) , 13770
Association between Statin Use and Diabetes Risk in Patients with Transient Ischemic Attack
Statin therapy can effectively reduce recurrent transient ischemic attack (TIA) risk. However, studies have reported that statin use is associated with incidence of diabetes mellitus (DM). Whether statin therapy remains associated with higher DM risk in patients with TIA remains unknown. This study investigated whether statin treatment influences incident DM risk in patients with TIA. We conducted a retrospective cohort study using the Longitudinal Health Insurance Database 2000. Participants who were newly diagnosed with TIA (ICD-9-CM code 435) from 1 January 1997 to 31 December 2011 were recruited. The Kaplan–Meier method and Cox proportional risk model of time-dependent covariance were used. We enrolled 8342 patients with newly diagnosed TIA from 1 January 1997 to 31 December 2011. Of these, 1255 patients were classified as statin users and 7087 as nonusers. During the 14-year follow-up, the incidence of newly diagnosed DM was 0.545-fold lower in the statins group compared with nonusers (95% confidence interval [CI] = 0.457–0.650). According to cumulative defined daily doses (cDDDs), the adjusted hazard ratios for DM were 0.689, 0.594, and 0.463 when patients were treated with statins at cDDDs = 28–89, 90–180, and >180, respectively. In patients with TIA, statin use is associated with a lower incident DM risk compared with the nonuse of statins.
- 23 October 2022
- Published by MDPI AG in International Journal of Environmental Research and Public Health
- Vol. 19 (21) , 13770
Open AccessAssociation between Statin Use and Diabetes Risk in Patients with Transient Ischemic Attack
Statin therapy can effectively reduce recurrent transient ischemic attack (TIA) risk. However, studies have reported that statin use is associated with incidence of diabetes mellitus (DM). Whether statin therapy remains associated with higher DM risk in patients with TIA remains unknown. This study investigated whether statin treatment influences incident DM risk in patients with TIA. We conducted a retrospective cohort study using the Longitudinal Health Insurance Database 2000. Participants who were newly diagnosed with TIA (ICD-9-CM code 435) from 1 January 1997 to 31 December 2011 were recruited. The Kaplan–Meier method and Cox proportional risk model of time-dependent covariance were used. We enrolled 8342 patients with newly diagnosed TIA from 1 January 1997 to 31 December 2011. Of these, 1255 patients were classified as statin users and 7087 as nonusers. During the 14-year follow-up, the incidence of newly diagnosed DM was 0.545-fold lower in the statins group compared with nonusers (95% confidence interval [CI] = 0.457–0.650). According to cumulative defined daily doses (cDDDs), the adjusted hazard ratios for DM were 0.689, 0.594, and 0.463 when patients were treated with statins at cDDDs = 28–89, 90–180, and >180, respectively. In patients with TIA, statin use is associated with a lower incident DM risk compared with the nonuse of statins.