Wenjuan Zhang
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Wenjuan Zhang has a total of 14 co-authors. Here are the top co-authors by number of shared publications:
- Xuming Zhuang
College of Chemistry and Chemical Engineering, Yantai University, Yantai 264005, China
2 shared publications - Bo Peng
School of Chemistry & Chemical Engineering, Yantai University, Yantai 264005, China
1 shared publication - Caimei Zhang
School of Chemistry & Chemical Engineering, Yantai University, Yantai 264005, China
1 shared publication - Chaoqiang Xiao
Shandong Dyne Marine Biopharmaceutical Co., Ltd , Beijing 100176
1 shared publication - Chunyuan Tian
School of Chemistry and Chemical Engineering, Yantai University, Yantai, 264005, China
1 shared publication - Dayong Shi
Shandong Dyne Marine Biopharmaceutical Co., Ltd., Weihai 264300, China
1 shared publication
Latest Publications
- Open Access
A Novel Molecularly Imprinted Electrochemiluminescence Sensor Based on Mxene Quantum Dots for Selective Detection of Oseltamivir in Biological Samples
Oseltamivir is a drug that has been widely used to prevent and treat influenza A and B. In this work, an ultrasensitive, simple, and novel electrochemiluminescence (ECL) sensor combined with molecularly imprinted polymers (MIP-ECL) based on a graphene-like two-dimensional material, Mxene quantum dots (MQDs) was constructed to selectively detect oseltamivir. A molecularly imprinted polymer membrane containing an oseltamivir template was constructed by electropolymerization and elution of modified MQDs on a glassy carbon electrode. Under optimized experimental conditions, the MIP-ECL sensor could detect oseltamivir in the range of 10−10 to 10−6 M (R2 = 0.9816), with a low limit of detection of 6.5 × 10−11 M (S/N = 3), and the recovery rates of oseltamivir in biological samples were 92.21–104.2%, with relative standard deviations of 3.70%~5.70%. The developed MIP-ECL sensor provides a new idea for detecting oseltamivir, which was successfully applied to the determination of oseltamivir in serum samples, indicating great potential for application in clinical diagnostics.
Open AccessA Novel Molecularly Imprinted Electrochemiluminescence Sensor Based on Mxene Quantum Dots for Selective Detection of Oseltamivir in Biological Samples
Oseltamivir is a drug that has been widely used to prevent and treat influenza A and B. In this work, an ultrasensitive, simple, and novel electrochemiluminescence (ECL) sensor combined with molecularly imprinted polymers (MIP-ECL) based on a graphene-like two-dimensional material, Mxene quantum dots (MQDs) was constructed to selectively detect oseltamivir. A molecularly imprinted polymer membrane containing an oseltamivir template was constructed by electropolymerization and elution of modified MQDs on a glassy carbon electrode. Under optimized experimental conditions, the MIP-ECL sensor could detect oseltamivir in the range of 10−10 to 10−6 M (R2 = 0.9816), with a low limit of detection of 6.5 × 10−11 M (S/N = 3), and the recovery rates of oseltamivir in biological samples were 92.21–104.2%, with relative standard deviations of 3.70%~5.70%. The developed MIP-ECL sensor provides a new idea for detecting oseltamivir, which was successfully applied to the determination of oseltamivir in serum samples, indicating great potential for application in clinical diagnostics.
- Open Access
Sensitive and Facile HCOOH Fluorescence Sensor Based on Highly Active Ir Complexes’ Catalytic Transfer Hydrogen Reaction
With several major polarity and weak optical properties, the sensitive detection of HCOOH remains a major challenge. Given the special role of HCOOH in assisting in the catalytic hydrogenation process of Ir complexes, HCOOH (as a hydrogen source) could rapidly activate Ir complexes as catalysts and further reduce the substrates. This work developed a facile and sensitive HCOOH fluorescence sensor utilizing an optimal catalytic fluorescence generation system, which consists of the phenyl-pyrazole-type Ir-complex PP-Ir-Cl and the coumarin-type fluorescence probe P-coumarin. The sensor demonstrates excellent sensitivity and specificity for HCOOH and formates; the limits of detection for HCOOH, HCOONa, and HCOOEt3N were tested to be 50.6 ppb, 68.0 ppb, and 146.0 ppb, respectively. Compared to previous methods, the proposed sensor exhibits good detection accuracy and excellent sensitivity. Therefore, the proposed HCOOH sensor could be used as a new detection method for HCOOH and could provide a new design path for other sensors.
Open AccessSensitive and Facile HCOOH Fluorescence Sensor Based on Highly Active Ir Complexes’ Catalytic Transfer Hydrogen Reaction
With several major polarity and weak optical properties, the sensitive detection of HCOOH remains a major challenge. Given the special role of HCOOH in assisting in the catalytic hydrogenation process of Ir complexes, HCOOH (as a hydrogen source) could rapidly activate Ir complexes as catalysts and further reduce the substrates. This work developed a facile and sensitive HCOOH fluorescence sensor utilizing an optimal catalytic fluorescence generation system, which consists of the phenyl-pyrazole-type Ir-complex PP-Ir-Cl and the coumarin-type fluorescence probe P-coumarin. The sensor demonstrates excellent sensitivity and specificity for HCOOH and formates; the limits of detection for HCOOH, HCOONa, and HCOOEt3N were tested to be 50.6 ppb, 68.0 ppb, and 146.0 ppb, respectively. Compared to previous methods, the proposed sensor exhibits good detection accuracy and excellent sensitivity. Therefore, the proposed HCOOH sensor could be used as a new detection method for HCOOH and could provide a new design path for other sensors.