Saman Rezai Moradali
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Saman Rezai Moradali has a total of 4 co-authors. Here are the top co-authors by number of shared publications:
- Hassan Montazam
Department of Genetics, Bonab Branch, Islamic Azad University, Bonab, Iran
1 shared publication - Hossein Soltanzadeh
Department of Genetics, Bonab Branch Islamic Azad University Bonab Iran
1 shared publication - Shima Fathi
Department of Genetics, Bonab Branch, Islamic Azad University, Bonab, Iran
1 shared publication - Zahra Asadi
Department of Genetics, Bonab Branch, Islamic Azad University, Bonab, Iran
1 shared publication
Latest Publications
- Open Access
- 29 July 2022
- Published by Maad Rayan Publishing Company in Addiction & Health
- Vol. 14 (3) , 214-217
MicroRNA-127 and MicroRNA-132 Expression in Patients with Methamphetamine Abuse in East Azerbaijan, Iran: A Case-Control Study
Background: Addiction is a personal and social problem worldwide, and has physical and psychological effects on consumers’ health. Recently, miRNAs have been described as noninvasive biomarkers. Currently, methamphetamine abuse (MA) is mainly diagnosed by chromatography. This study aimed to investigate the expression and diagnostic value of miR-127 and miR-132 in blood samples of patients with MA and non-user healthy controls. Methods: A total of 60 patients with MA (case group) and 60 non-user healthy individuals (control group) were selected from Tabriz, East Azerbaijan, Iran. Peripheral blood was obtained and total RNA was extracted. Then, cDNA synthesis was performed and miR-127 and miR-132 expression was evaluated using real time polymerase chain reaction (PCR) method. Findings: The results of this study demonstrated that miR-127 was significantly lower (0.042-fold change) in patients with MA than in the control group (P<0.05). However, miR-132 was significantly higher (7.1-fold change) in patients with MA than in the control group (P<0.05). Conclusion: In general, expression of miR-127 and miR-132 may alter in patients with MA. Further studies are needed to identify underlying molecular mechanisms in patients with MA.
- 29 July 2022
- Published by Maad Rayan Publishing Company in Addiction & Health
- Vol. 14 (3) , 214-217
Open AccessMicroRNA-127 and MicroRNA-132 Expression in Patients with Methamphetamine Abuse in East Azerbaijan, Iran: A Case-Control Study
Background: Addiction is a personal and social problem worldwide, and has physical and psychological effects on consumers’ health. Recently, miRNAs have been described as noninvasive biomarkers. Currently, methamphetamine abuse (MA) is mainly diagnosed by chromatography. This study aimed to investigate the expression and diagnostic value of miR-127 and miR-132 in blood samples of patients with MA and non-user healthy controls. Methods: A total of 60 patients with MA (case group) and 60 non-user healthy individuals (control group) were selected from Tabriz, East Azerbaijan, Iran. Peripheral blood was obtained and total RNA was extracted. Then, cDNA synthesis was performed and miR-127 and miR-132 expression was evaluated using real time polymerase chain reaction (PCR) method. Findings: The results of this study demonstrated that miR-127 was significantly lower (0.042-fold change) in patients with MA than in the control group (P<0.05). However, miR-132 was significantly higher (7.1-fold change) in patients with MA than in the control group (P<0.05). Conclusion: In general, expression of miR-127 and miR-132 may alter in patients with MA. Further studies are needed to identify underlying molecular mechanisms in patients with MA.