Laura Jerono
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Laura Jerono has a total of 10 co-authors. Here are the top co-authors by number of shared publications:
- Alessandro Bozzato
Department of Otorhinolaryngology, Saarland University Medical Center, D-66421 Homburg, Germany
1 shared publication - Anna-Katharina Rink
Department for Otorhinolaryngology, Head and Neck Surgery, Saarland University Medical Center, 66421 Homburg, Germany
1 shared publication - Armand Koch
Department for Otorhinolaryngology, Head and Neck Surgery, Saarland University Medical Center, 66421 Homburg, Germany
1 shared publication - Bernhard Schick
Department of Otorhinolaryngology, Saarland University, Kirrberger Straße 100, 66421 Homburg, Germany
1 shared publication - Dietmar Hecker
Department of Otorhinolaryngology, Head and Neck Surgery, Saarland University Hospital, Homburg, Germany
1 shared publication - Hans Scherer
Department of Otolaryngology Head and Neck Surgery and Institute of Clinical Chemistry and Pathobiochemistry Charité‐Universitätsmedizin Berlin 13353 Berlin Germany
1 shared publication
Latest Publications
- Open Access
- 30 November 2022
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 11 (23) , 7124
Identification of Neural Mechanisms in First Single-Sweep Analysis in oVEMPs and Novel Normative Data
Background: Bone-conducted (BC) VEMPs provide important tools for measuring otolith function. However, two major drawbacks of this method are encountered in clinical practice—small n10 amplitude and averaging technique. In this study, we present the results of a new VEMP setup measuring technique combined with a novel single-sweep analysis. Methods: The study included BC oVEMP data from 92 participants for the evaluation of normative data using a novel analysis technique. For evaluating test-retest reliability, the intraclass correlation coefficient (ICC) was used. Results: We found significant n10 amplitude differences in single-sweep analyses after the first and second measurements. Thereby, mathematical analyses of the head movement did not show any differences in the first or second measurements. The normative n10 amplitude was 20.66 µV with an asymmetric ratio (AR) of 7%. The new value of late shift difference (LSD) was 0.01 ms. The test retest-reliability showed good to excellent ICC results in 9 out of 10 measurements. Conclusions: Our results support a phenomenon in single-sweep analysis of the first stimuli independent of head movement and signal morphology. Furthermore, the values obtained with the new measurement method appear to be more sensitive and may allow an extended diagnostic range due to the new parameter LSD.
- 30 November 2022
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 11 (23) , 7124
Open AccessIdentification of Neural Mechanisms in First Single-Sweep Analysis in oVEMPs and Novel Normative Data
Background: Bone-conducted (BC) VEMPs provide important tools for measuring otolith function. However, two major drawbacks of this method are encountered in clinical practice—small n10 amplitude and averaging technique. In this study, we present the results of a new VEMP setup measuring technique combined with a novel single-sweep analysis. Methods: The study included BC oVEMP data from 92 participants for the evaluation of normative data using a novel analysis technique. For evaluating test-retest reliability, the intraclass correlation coefficient (ICC) was used. Results: We found significant n10 amplitude differences in single-sweep analyses after the first and second measurements. Thereby, mathematical analyses of the head movement did not show any differences in the first or second measurements. The normative n10 amplitude was 20.66 µV with an asymmetric ratio (AR) of 7%. The new value of late shift difference (LSD) was 0.01 ms. The test retest-reliability showed good to excellent ICC results in 9 out of 10 measurements. Conclusions: Our results support a phenomenon in single-sweep analysis of the first stimuli independent of head movement and signal morphology. Furthermore, the values obtained with the new measurement method appear to be more sensitive and may allow an extended diagnostic range due to the new parameter LSD.