Sarah Hsu
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Sarah Hsu has a total of 6 co-authors. Here are the top co-authors by number of shared publications:
- Anna Chen Arroyo
Division of Pulmonary, Allergy & Critical Care Medicine, Stanford University School of Medicine, Stanford, CA
1 shared publication - Camille E. Powe
Diabetes Unit, Endocrine Division, Department of Medicine Massachusetts General Hospital Boston Massachusetts USA
1 shared publication - Carlos Arturo Camargo
Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, United States
1 shared publication - Kaitlyn James
Division of Gynecologic Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
1 shared publication - Mohammad Kamal Faridi
Massachusetts General Hospital, Department of Emergency Medicine, Boston, Massachusetts
1 shared publication - Orianne Dumas
Université Paris-Saclay, UVSQ, Univ. Paris-Sud, Inserm, Équipe d’Épidémiologie respiratoire intégrative, CESP, Villejuif, France
1 shared publication
Latest Publications
- Open Access
Cohort Study of Maternal Gestational Weight Gain, Gestational Diabetes, and Childhood Asthma
Data on the association of maternal gestational weight gain (GWG) and gestational diabetes mellitus (GDM) with childhood asthma are limited and inconsistent. We aimed to investigate these associations in a U.S. pre-birth cohort. Analyses included 16,351 mother–child pairs enrolled in the Massachusetts General Hospital Maternal-Child Cohort (1998–2010). Data were obtained by linking electronic health records for prenatal visits/delivery to determine BMI, GWG, and GDM (National Diabetes Data Group criteria) and to determine asthma incidence and allergies (atopic dermatitis or allergic rhinitis) for children. The associations of prenatal exposures with asthma were evaluated using logistic regression adjusted for maternal characteristics. A total of 2306 children (14%) developed asthma by age 5 years. Overall, no association was found between GWG and asthma. GDM was positively associated with offspring asthma (OR 1.46, 95% CI 1.14–1.88). Associations between GDM and asthma were observed only among mothers with early pregnancy BMI between 20 and 24.9 kg/m2 (OR 2.31, CI 1.46–3.65, p-interaction 0.02). We report novel findings on the impact of prenatal exposures on asthma, including increased risk among mothers with GDM, particularly those with a normal BMI. These findings support the strengthening of interventions targeted toward a healthier pregnancy, which may also be helpful for childhood asthma prevention.
Open AccessCohort Study of Maternal Gestational Weight Gain, Gestational Diabetes, and Childhood Asthma
Data on the association of maternal gestational weight gain (GWG) and gestational diabetes mellitus (GDM) with childhood asthma are limited and inconsistent. We aimed to investigate these associations in a U.S. pre-birth cohort. Analyses included 16,351 mother–child pairs enrolled in the Massachusetts General Hospital Maternal-Child Cohort (1998–2010). Data were obtained by linking electronic health records for prenatal visits/delivery to determine BMI, GWG, and GDM (National Diabetes Data Group criteria) and to determine asthma incidence and allergies (atopic dermatitis or allergic rhinitis) for children. The associations of prenatal exposures with asthma were evaluated using logistic regression adjusted for maternal characteristics. A total of 2306 children (14%) developed asthma by age 5 years. Overall, no association was found between GWG and asthma. GDM was positively associated with offspring asthma (OR 1.46, 95% CI 1.14–1.88). Associations between GDM and asthma were observed only among mothers with early pregnancy BMI between 20 and 24.9 kg/m2 (OR 2.31, CI 1.46–3.65, p-interaction 0.02). We report novel findings on the impact of prenatal exposures on asthma, including increased risk among mothers with GDM, particularly those with a normal BMI. These findings support the strengthening of interventions targeted toward a healthier pregnancy, which may also be helpful for childhood asthma prevention.