Dmitri Wiederschain
Research Subjects
Dmitri Wiederschain has a total of 25 co-authors. Here are the top co-authors by number of shared publications:
- Abha Dhaneshwar
Jounce Therapeutics, Cambridge, United States
54 shared publications - Alexa Diiorio
Jounce Therapeutics, Cambridge, United States
54 shared publications - Allison Goodman
Jounce Therapeutics, Cambridge, United States
54 shared publications - Amy Mueller
Jounce Therapeutics, Cambridge, United States
54 shared publications - Ben Umiker
Jounce Therapeutics, Cambridge, United States
54 shared publications - Christina Meyer
Takeda Oncology, Cambridge, MA, United States
54 shared publications
Latest Publications
- Open Access
- 27 November 2025
- Published by American Association for Cancer Research (AACR)
Figure S7 from Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
A set of 23 anti-LILRB2 antibodies were tested for their ability to block HLA-G tetramer binding to LILRB2 and induce TNF alpha in a macrophage activation assay.
- 27 November 2025
- Published by American Association for Cancer Research (AACR)
Open AccessFigure S7 from Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
A set of 23 anti-LILRB2 antibodies were tested for their ability to block HLA-G tetramer binding to LILRB2 and induce TNF alpha in a macrophage activation assay.
- Open Access
- 27 November 2025
- Published by American Association for Cancer Research (AACR)
Figure S3 from Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
Example gating strategy for blood monocytes
- 27 November 2025
- Published by American Association for Cancer Research (AACR)
Open AccessFigure S3 from Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
Example gating strategy for blood monocytes
- Open Access
- 27 November 2025
- Published by American Association for Cancer Research (AACR)
Figure S5 from Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
Example gating strategy in vitro differentiated GM-CSF and IL-4 Dendritic Cells
- 27 November 2025
- Published by American Association for Cancer Research (AACR)
Open AccessFigure S5 from Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
Example gating strategy in vitro differentiated GM-CSF and IL-4 Dendritic Cells
- Open Access
- 27 November 2025
- Published by American Association for Cancer Research (AACR)
Figure S8 from Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
Changes in gene expression by JTX-8064 in both macrophages and dendritic cells 6 days on treatment during differentiation
- 27 November 2025
- Published by American Association for Cancer Research (AACR)
Open AccessFigure S8 from Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
Changes in gene expression by JTX-8064 in both macrophages and dendritic cells 6 days on treatment during differentiation
- Open Access
- 27 November 2025
- Published by American Association for Cancer Research (AACR)
Figure S4 from Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
Example gating strategy in vitro differentiated M-CSF macrophages
- 27 November 2025
- Published by American Association for Cancer Research (AACR)
Open AccessFigure S4 from Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
Example gating strategy in vitro differentiated M-CSF macrophages
- Open Access
- 27 November 2025
- Published by American Association for Cancer Research (AACR)
Figure S2 from Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
Example gating strategy for tumor samples in order to acquire CD163 and LILRB2 + cells
- 27 November 2025
- Published by American Association for Cancer Research (AACR)
Open AccessFigure S2 from Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
Example gating strategy for tumor samples in order to acquire CD163 and LILRB2 + cells
- Open Access
- 27 November 2025
- Published by American Association for Cancer Research (AACR)
Figure S6 from Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
A Neutrophil activation assay which measures the frequency CD11b high expression by flow on neutrophils isolated from whole blood
- 27 November 2025
- Published by American Association for Cancer Research (AACR)
Open AccessFigure S6 from Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
A Neutrophil activation assay which measures the frequency CD11b high expression by flow on neutrophils isolated from whole blood
- Open Access
- 27 November 2025
- Published by American Association for Cancer Research (AACR)
Figure S10 from Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
Pembrolizumab pharmacodynamic response in histoculture as measured by IFN gamma signature score
- 27 November 2025
- Published by American Association for Cancer Research (AACR)
Open AccessFigure S10 from Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
Pembrolizumab pharmacodynamic response in histoculture as measured by IFN gamma signature score
- Open Access
- 27 November 2025
- Published by American Association for Cancer Research (AACR)
Figure S1 from Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
Tumor samples used in flow cytometry analysis, in this table the tumor type, the pathology, the total events and the number of CD11b+ cells are shown
- 27 November 2025
- Published by American Association for Cancer Research (AACR)
Open AccessFigure S1 from Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
Tumor samples used in flow cytometry analysis, in this table the tumor type, the pathology, the total events and the number of CD11b+ cells are shown
- Open Access
- 27 November 2025
- Published by American Association for Cancer Research (AACR)
Figure S9 from Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
Sensitivity of LILRB2 as a predictive biomarker for pharmacodynamic response as measured by the macrophage polarization score in histoculture explant cultures.
- 27 November 2025
- Published by American Association for Cancer Research (AACR)
Open AccessFigure S9 from Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
Sensitivity of LILRB2 as a predictive biomarker for pharmacodynamic response as measured by the macrophage polarization score in histoculture explant cultures.