Michael St. John James
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Michael St. John James has a total of 4 co-authors. Here are the top co-authors by number of shared publications:
- Edward L. Bolt
School of Life Sciences, University of Nottingham
1 shared publication - Ivana Ivančić-Baće
Faculty of Science, University of Zagreb, 10000 Zagreb, Croatia
1 shared publication - Liu He
School of Life Sciences, University of Nottingham, Nottingham NG7 2UH, UK
1 shared publication - Marin Radovcic
Department of Biology, Faculty of Science, University of Zagreb, 10000, Zagreb, Croatia
1 shared publication
Latest Publications
- Open Access
Cas3 Protein—A Review of a Multi-Tasking Machine
Cas3 has essential functions in CRISPR immunity but its other activities and roles, in vitro and in cells, are less widely known. We offer a concise review of the latest understanding and questions arising from studies of Cas3 mechanism during CRISPR immunity, and highlight recent attempts at using Cas3 for genetic editing. We then spotlight involvement of Cas3 in other aspects of cell biology, for which understanding is lacking—these focus on CRISPR systems as regulators of cellular processes in addition to defense against mobile genetic elements.
Open AccessCas3 Protein—A Review of a Multi-Tasking Machine
Cas3 has essential functions in CRISPR immunity but its other activities and roles, in vitro and in cells, are less widely known. We offer a concise review of the latest understanding and questions arising from studies of Cas3 mechanism during CRISPR immunity, and highlight recent attempts at using Cas3 for genetic editing. We then spotlight involvement of Cas3 in other aspects of cell biology, for which understanding is lacking—these focus on CRISPR systems as regulators of cellular processes in addition to defense against mobile genetic elements.